Module 1 Digestive System Flashcards
Functions of the digestive sytem
acquire food
process food
extract usable nutrients from food
void unusable wastes
GI Tract consists of
Mouth, esophagus, stomach, Small intestine, Large intestine, anus
How does the nervous system affect digestive motility?
the rate of movement or rate of peristalsis
How does the nervous system affect digestive blood supply?
which affects diffusion gradients and the performance of smooth muscle
The parasympathetic input to the digestive system includes
involuntary stimulation of smooth muscle. The parasympathetic system increases digestive performance mostly by increasing motility and enzyme secretion.
The sympathetic input to the digestive system includes
involuntary stimulation of smooth muscle. The sympathetic system decreases digestive performance mostly by decreasing motility, enzyme secretion, and blood supply.
The ENS (Enteric Nervous System) contains 2 plexuses
submucosal or Meissner’s plexus
myenteric or Auerbach’s plexus:
myenteric or Auerbach’s plexus:
This nerve network lies between the longitudinal and circular muscle layers and controls motility.
submucosal or Meissner’s plexus:
This nerve network lies in the submucosal region of the wall and controls the function of the inner wall by influencing secretions, blood flow, and ton
Myenteric Plexus stimulation affects movement through at least 5 inhibitory or excitatory pathways:
Increased tonic contraction (tone) of gut wall
Increased amplitude of rhythmic contractions
Increased frequency of rhythmic contractions
Increased velocity of conduction of excitatory waves
Inhibition of sphincters (via an inhibitory NT such as vasoactive intestinal polypeptide) which impede movement from region to region; ie: pyloric sphincter between stomach and duodenum (so they remain open and food moves more easily)
Submucosal Plexus Function
local control
Intestinal secretion
Absorption
Contraction of the submucosal muscle (controls folding of GI mucosa)
Neurotransmitters of Enteric Neurons
Acetylcholine: Norepinephrine: ATP Serotonin Dopamine Cholecystokinin Vasoactive intestinal polypeptide Somatostatin Leu-enkephalin Met-enkephalin Bombesin Epinephrine
Acetylcholine function in Enteric neurons
excites gut (parasympathetic)
Norepinephrine function in Enteric Neurons
inhibits gut (sympathetic)
Epinephrine function in Enteric Neurons
released by adrenal medulla, travels by bloodstream, inhibits gut