module 1

Question 1

adverse effects

Answer 1

undesirable effects that is direct response to 1+ drugs

Question 2

pharmacotherapeutics

Answer 2

treatment of pathological conditions through use of drugs

Question 3

pharmacokinetics

Answer 3

what happens to a drug from entering the body until parent drug & metabolites have left the body.

Question 4

pharmacodynamics

Answer 4

study of biochemical & physiological interactions of drugs at site of activity.

Question 5

bioavailability

Answer 5

measure of drug absorption for given drug & route. rated from 0-100%

Question 6

first pass effect

Answer 6

intitial metabolism of liver form drug absorbed in gastrointestinal tract before drug reaches systematic circulation through the blood stream

Question 7

contraindications and precautions

Answer 7

renders form of undesirable symptoms from treatment

Question 8

drug interaction

Answer 8

alteration in pharmacokinetic or pharmacologic activity of a given drug with presence of 1+ drugs. usually effects of enzymes

Question 9

prototype drug

Answer 9

.

Question 10

pharmacogenomics

Answer 10

influence of genetic factors on drug response

Question 11

generic name

Answer 11

name given to drug by united states adopted names council. also called nonproprietary name. not protected by trademark

Question 12

agonist

Answer 12

drug that binds to and stimulates the activity of one or more receptors in the body

Question 13

antagonist

Answer 13

drug that binds to and inhibits the activity of one or more receptors also known as inhibitor

Question 14

therapeutic index

Answer 14

ratio between toxic and therapeutic concentrations of drug

Question 15

therapetuic range

Answer 15

the level at which it is safe to take to give you a therapeutic response but also the level where it is not lethal

Question 16

steady state

Answer 16

physiologic state where amount of drug absorbed is equal to amount of drug removed

Question 17

P450

Answer 17

microsomal enzymes that metabolize naturally occurring substances such as fatty acids

Question 18

loading dose

Answer 18

bunch of drug is administered up front in order to prepare for maintenance

Question 19

maintenance dose

Answer 19

dosage used every day to keep a steady state