MODULE 1 Flashcards
Separation and analysis of chemical substances; deals with the chemical composition
ANALYTICAL CHEMISTRY
identifying components
QUALITATIVE DETERMINATION
Light absorption (use UV-vis spectroscopy, IR fingerprinting)
QUALITATIVE DETERMINATION
Chromatography
QUALITATIVE DETERMINATION
Amount or percentage of one or more constituents
QUANTITATIVE ANALYSIS
application in pharmaceuticals (dosage, analysis of body fluids, pollutants(water and air), soils
QUANTITATIVE ANALYSIS
Food labeling
QUANTITATIVE ANALYSIS
Measurement of physical properties such as density, refractive index, absorption or polarization of light, electromotive force, magnetic susceptibility
PHYSICAL METHODS
LCMS
Liquid Chromatography Mass Spectroscopy
ANALYTICAL PROCESSES
- PLAN OF ANALYSIS
- SAMPLING
- SAMPLE PREPARATION
- MEASURING THE SAMPLE
- CALCULATIONS AND EVALUATIONS OF RESULTS
- DRAWING CONCLUSIONS
What analytical information is needed?
PLAN OF ANALYSIS
What analyses are needed to provide the information?
PLAN OF ANALYSIS
What analytical method should be used?
PLAN OF ANALYSIS
Sample readiness for analysis
SAMPLING PREPARATION
Physical state
SAMPLING PREPARATION
Homogeneity
SAMPLING PREPARATION
DERIVATIZATION
SAMPLING PREPARATION
REACTIVITY
SAMPLING PREPARATION
Prepare the equipment/ apparatus
SAMPLING PREPARATION
Calibration
SAMPLING PREPARATION
Operational
SAMPLING PREPARATION
Knowledge of technicians or operations
SAMPLING PREPARATION
Handling of data
CALCULATIONS AND EVALUATIONS
Numbers are the basis of decision
DRAWING CONCLUSIONS
Assumption is that the
recording and reporting of
data are correct
MEASURING THE SAMPLE
HANDLING OF DATA
MEASURING THE SAMPLE
