modern treatment of disease xx-modern Flashcards
- what was fleming determined to do?
to find a better way to treat infected wounds and conducted detailed experiments
- what happens in 1928 when fleming went on holiday?
left several plates of Staphylococcus germs on a bench in his laboratory;
- what happened to the plates of germs fleming left?
when he came home, he noticed a large blob of mould in one of the
dishes
- what did fleming notice had happened to the germs?
he noticed that the Staphylococcus germs next to the mould had been killed
- after fleming took a sample of the mould what did he find out?
it was penicillin mould; it appeared that a spore from this mould, grown in a room below Fleming’s, had floated up the stairs and into his laboratory
- what did fleming think penicillin was?
a natural antiseptic, but it was an antibiotic
- what did fleming realise about penicillin?
Fleming realised the germ-killing capabilities of penicillin and published his findings that year.
- why did people not think flemings work was a bug break through?
because he never tested it on an animal or person
- who tested penicillin on an animal?
in 1930 Scientists Howard Florey and Ernst Chain successfully tested penicillin on eight mice.
Their next move was to test it on humans and, over a period of months, they produced enough penicillin to use on a patient with a bad infection.
- why was penicillin vital in ww2?
it was vital in treating soldiers with infected wounds.
- why was ww2 a major factor in transforming supply of penicillin?
it was used to treat soldiers
- what happens in june 1941
Florey met with the US government who agreed to pay several huge chemical companies to make millions of gallons of it.
- how many treated soldiers were being treated by the end of ww2?
250,000 soldiers
- what did drug companies plan to do with penicillin when war was over?
Drug companies began using their production methods to make penicillin for public use as soon as the war ended.
- what did the discovery of penicillin mean for pharmaceutical industry?
discovery led to huge government-sponsored programmes to develop
- what were the key developments
i n health and medicine since
1945?
•body and disease
•treatment
•surgery
- what were the key developments in body and disease in health and medicine since 1945?
• 1953: scientists at Cambridge University map out the DNA structure; the understanding of DNA leads to such developments as gene therapy,
• 1970s and 1980s: technology that we take for granted today was developed: CAT scanners that produce 3D images of the body
• MRI scanning
- what were the key developments in treatment in health and medicine since 1945?
• Between 1946 and 1969: free vaccines available in the UK for TB, diphtheria, whooping cough, tetanus, polio, measles and rubella
• 1978: doctors use IVF fertility treatment to help childless women become pregnant
- what were the key developments in surgery in health and medicine since 1945?
first open-heart surgery to repair a ‘hole’ in a baby’s heart; first pacemaker is fitted in 1958, followed by the first British heart transplant
- what was the impact of the first and second world wars?
• x-rays
•plastic surgery
•blood transfusions
- what was the impact of first and second world wars on x-rays?
•Discovered in 1895; hospitals used them to look for broken bones and disease
• During the war, proved their
effectiveness on the battlefield when
mobile X-ray machines were used;
developed by Polish scientist Marie Curie
•Allowed surgeons to find out exactly
where in the wounded soldier’s body
bullets or pieces of shrapnel had
lodged - without having to cut him open
- what was the impact of first and second world wars on plastic surgery?
During the First World War, Harold Gillies set up a special unit to graft (transplant) skin and treat men suffering from severe facial
wounds
Queen’s Hospital in Kent opened in 1917; by 1921 it provided over 1000 beds for soldiers with severe facial wounds
- what was the impact of first and second world wars on blood transfusions?
In 1900, Karl Landsteiner discovered blood groups, which helped doctors work out that a transfusion only worked if the donor’s blood type matched the receiver’s
It was not possible to store blood for long until 1914 when Albert Hustin discovered that sodium citrate stopped blood from clotting
Large blood banks developed in both the USA and Britain during the Second World War
- how did the war develop treatment of broken bones?
the Army Leg Splint was developed, which kept a broken leg ‘in traction’. The splint is still in use today.