Mode of Action of Antimicrobial Agents Flashcards

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1
Q

Disrupts cell wall synthesis or integrity

A

Beta-lactams (penicillins and cephalosporins)
Glycopeptides (vancomycin)

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2
Q

Disrupts cell membrane structure or function

A

Polymyxins (polymyxin B)
Bacitracin

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3
Q

Inhibits protein synthesis

A

Aminoglycosides (gentamicin)
Tetracyclines
Macrolides (erythromycin)
Lincosamides (clindamycin)

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4
Q

Inhibits nucleic acid synthesis or integrity

A

Quinolones (ciprofloxacin)
Metronidazole

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5
Q

Inhibits metabolite
synthesis

A

Sulfamethoxazole Trimethoprim

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6
Q

Staphylococcus aureus

A

mecA

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7
Q

Streptococcus pneumoniae

A

pbp1a and pbp1b

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8
Q

Gram-negatives Enterococcus
Vancomycin

A

vanA, vanB, vanC, vanD,
vanE, vanG

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9
Q

Salmonella

A

gyrA, gyrB, parC, parE

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10
Q

Mycobacterium tuberculosis rofampin

A

rpoB

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