Mode of Action of Antimicrobial Agents Flashcards
1
Q
Disrupts cell wall synthesis or integrity
A
Beta-lactams (penicillins and cephalosporins)
Glycopeptides (vancomycin)
2
Q
Disrupts cell membrane structure or function
A
Polymyxins (polymyxin B)
Bacitracin
3
Q
Inhibits protein synthesis
A
Aminoglycosides (gentamicin)
Tetracyclines
Macrolides (erythromycin)
Lincosamides (clindamycin)
4
Q
Inhibits nucleic acid synthesis or integrity
A
Quinolones (ciprofloxacin)
Metronidazole
5
Q
Inhibits metabolite
synthesis
A
Sulfamethoxazole Trimethoprim
6
Q
Staphylococcus aureus
A
mecA
7
Q
Streptococcus pneumoniae
A
pbp1a and pbp1b
8
Q
Gram-negatives Enterococcus
Vancomycin
A
vanA, vanB, vanC, vanD,
vanE, vanG
9
Q
Salmonella
A
gyrA, gyrB, parC, parE
10
Q
Mycobacterium tuberculosis rofampin
A
rpoB