Mod11: Anesthetic Considerations for Radiology & Radiation Therapy Flashcards
Anesthetic Considerations for Radiology & Radiation Therapy
Why must caution be used with IV contrast agents during Radiology & Radiation Therapy procedures?
It’s not uncommon to see people with IV contrats allergies
Anesthetic Considerations for Radiology & Radiation Therapy
Why is allergy to IV contrast mostly associated with older agents?
Older ionized contrast media were hyperosmolar and toxic
Pts who received IV contrast in the 70s or 80s and had a reaction, will have it documented in their chart as an “allergy”.
These pts may benefit from Benadryl or a steroid pretreatment
If history of Anaphylactic reaction or a more recent history of allergic raction, talk to the physician about maybe trying out something else besides IV contrast (e.g., cancelling the procedure, non using contrast at all)
Anesthetic Considerations for Radiology & Radiation Therapy
How do new IV contrast agents differ from the older agents?
Newer non-ionized contrast media have lower osmolality and improved side-effects
Anesthetic Considerations for Radiology & Radiation Therapy
Predisposing factors to adverse reactions from contrast media include a history of:
Bronchospasm - Allergy - Cardiac disease
Hypovolemia - Hematologic disease - Renal dysfunction
Extremes of age - Anxiety
Medications (Beta-blockers, aspirin, and NSAIDs)
Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Bronchospasm a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Allergy a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Cardiac disease a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Hypovolemia a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Hematologic disease a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Renal dysfunction a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is Extremes of age a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of Anxiety a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
Why is a history of using some Medications (Beta-blockers, aspirin, and NSAIDs) a Predisposing factor to adverse reactions from contrast media?
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Anesthetic Considerations for Radiology & Radiation Therapy
How does a mild reaction to IV contrast agents manifest?
Nausea - Perception of warmth - Headache
Itchy rash - Mild urticaria
Not really considered a reaction; more of a side effect from the contrast
Anesthetic Considerations for Radiology & Radiation Therapy
How does a Severe reaction to IV contrast agents manifest?
Arrhythmias - Bronchospasm - Dyspnea - Chest pain
Feeling faint - Rigors - Vomiting - renal failure
Severe urticaria
Anesthetic Considerations for Radiology & Radiation Therapy
How does a Life-threatening reaction to IV contrast agents manifest?
Arrhythmias - Cardiac arrest
Glottic edema/bronchospasm - Pulmonary edema
Seizures/unconsciousness.
Anesthetic Considerations for Radiology & Radiation Therapy
How are reactions to IV contrast treated?
O2 - Bronchodilators - Epinephrine
Corticosteroids - Antihistamines - Intubation
Circulatory support with IV fluids/pressors
Also refer to lecture on Anaphylaxis reaction
Anesthetic Considerations for Radiology & Radiation Therapy
Contrast-induced nephropathy accounts for what % of hospital-acquired renal failure
10%
Anesthetic Considerations for Radiology & Radiation Therapy
Contrast-induced nephropathy is more common in which clinical conditions?
Renal insufficiency
DM
NSAIDs
Anesthetic Considerations for Radiology & Radiation Therapy
How could the risk of Contrast-induced nephropathy be reduced in susceptible patients?
Adequate hydration
Monitoring U/O
Low osmolarity contrast media
Administer NaHCO3 IV infusion 1hr before contrast administration
Anesthetic Considerations for Radiology & Radiation Therapy
Radiation exposure is a unique hazard. What could it lead to?
Leukemia and fetal abnormalities