MOD F TECH 46 Poisoning and Substance misuse Flashcards

1
Q

Definition of a Poison

A

•A poison (toxin) is any substance which, when taken into the body in sufficient quantity, may cause temporary or permanent damage either endangering life or seriously impairing body functions.

•Once in the body poisons attack vital organs, such as the brain, heart, lungs, liver and kidneys. Different poisons attack different organs and produce varying signs and symptoms – they may develop quickly or over a number of days.

•Although a patient may well recover, permanent damage may occur to internal organs.

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2
Q

Types of Poisons

A

Poisons are Classified as:

Corrosive / Irritants

Non - Corrosive

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3
Q

Overdose and poisoning is a common complaint we are called to in the Ambulance Service and accounts for 140,000 hospital admissions per year.

Poisons are usually taken in one of following ways:

Accidentally or Intentionally (self-harm), mal-intent

or non-accidentally.

A number of factors will affect severity and

outcome including age, toxicity of the agent,

quantity and route of exposure

A
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4
Q

How Poisons enter the Body

A

Inhalation – fumes, gases, solvents, vapours

Ingestion – liquids, or solids by mouth

Injection – needles, animal and insect bites

Absorption – pesticides or herbicides through the skin and eyes

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5
Q

JRCALC Principles of treatment

A

•Identify poisons / agent – household product, pharmaceutical / recreational substance, plant / fungi, alcohol, chemicals (CBRNe) or even cosmetics?

•Specific treatment for the type of poison

•Rapid access to hospital

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6
Q

Duty of Care

A
  • It is not uncommon to find a patient who has or claims to have taken an overdose and subsequently refuses treatment or admission to hospital.
  • If this happens then ensure that their mental health, capacity and suicide risk have all been assessed.
  • If despite reasonable persuasion the patient still refuses treatment then it is not acceptable to leave them in a potentially dangerous situation without any access to care – do the police need to attend and / or a local mental health team?
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7
Q

History

A
  • The event e.g.: when did it happen
  • Drug /substance ingested
  • Quantity of the drug/substance ingested
  • Collect all suspected drugs/substances
  • Mode of poisoning e.g. ingestion, inhalation
  • Additional contributory factors – alcohol
  • Has any treatment occurred yet?
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8
Q

Corrosive / Irritant Substances

A

Clinical Signs:

üLips mouth show signs of corrosion

üBurning / staining

üSevere pain / swelling mouth and throat

üWretching / vomiting

üAbdominal cramps / diarrhoea

üDifficult speech due to swelling of the mucosa

üOdours on breath

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9
Q

Management of Corrosive / Irritant Substances

A

üEnsure open airway

üO2 therapy (Paraquat with caution – only in hypoxic pt’s with SpO2 <88% aiming for target saturation

of 88-92%)

üPulse

üNever induce vomiting

üAscertain poison taken / time / quantity

Nil by mouth unless directed to by container

/ petroleum dilute = MILK

Retain samples for = Identification

Transport to hospital = Urgently

Retain vomit for = Analysis

Taking a relative to hospital with the patient if possible

unconscious Patient:

Ensure open airway

Administer oxygen

Assist ventilation if necessary

CPR = Bag / Mask Mechanical resuscitator

Avoiding Contamination

B.M.

Transport in Recovery position

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10
Q

Non – Corrosive Substances

A

Neurotoxic poisons

Generally affects the nervous system by depressing vital functions; more common ones are:

q

qMorphine

q Heroin

Barbiturates

Clinical Signs

qPinpoint pupils (with opiates

q Slow and shallow breathing

(depressed respiration)

q Lethargy and reduction in activity

q Vomiting and diarrhoea

q Loss of consciousness

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11
Q

Management of Neurotoxic Poisons

A

qEnsuring open airway

q Oxygen therapy in high concentrations

q Assist ventilation if necessary

q CPR if required

q Do not induce vomiting

q Copious amounts of water / milk to dilute and delay absorption

qPlace in recovery position

and do not induce vomiting, if the

patients unconscious

q Keep patient still and quiet

to reduce pulse rate

q Do not allow the patient to walk

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12
Q

Poisonous Gases

A

•Because of the variety of poisons which can be inhaled and their differing effects on the body, there are few clear cut signs and symptoms

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13
Q

Management of
Poisonous Gases

A

Approach the scene with care

Remove the patient from the poison source

Ensure open airway

Administer high concentrations of oxygen

CPR if required

Loosen and remove contaminated clothing

Identify what type of gas was inhaled

Inform the receiving hospital if possible (pre-alert)

Transport to hospital

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14
Q

Paraquat Poisoning Cases

Management of
Paraquat Poisoning

A

•In addition to the usual clinical signs, there may be evidence of burning around the mouth.

Open airway

O2 therapy only when hypoxaemic to maintain SAO2 @88-92%

Artificial ventilation only by bag valve mask.

Do not encourage the patient to vomit

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15
Q

Pesticide and
Herbicide Poisoning

A
  • In addition to the usual clinical signs there may be evidence of burning staining around the mouth, tongue and lips
  • Remove the patient from the source
  • Ensure open airway
  • Assisted ventilation Bag Mask / Ventilator providing O2
  • Remove contaminated clothing taking care not to contaminate yourself

qWash contaminated skin thoroughly

q If eyes contaminated irrigate with copious amounts of clean water, covering both with soft pad

q Take to hospital for examination (eye causality)

q Take with you, container / sample of the substance / vomit for analysis

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16
Q

National Poisons Information Service

A

•NPIS is a service commissioned by the Health Protection Agency that provides expert advice on all aspects of acute and chronic poisoning

•It promotes, supports and develops best practice for the management of cases of poisoning in NHS facilities

•However it does not answer queries from the public but supports NHS Direct (0845 4647) and NHS24 (08454 24 24 24)

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17
Q

Alcohol Poisoning

A

•Alcohol intoxication is a common emergency & can pose a major problem when combined with drugs in overdose

•When combined with opiate drugs or sedatives, it will further decrease LOC & increase the risk of aspiration of vomit

•Pay particular to airway management & use the recovery position where appropriate

•Always remember to check BM as hypoglycaemia can mimic the signs of alcohol intoxication

18
Q

Drug Overdoses

A
  • Could be accidental or intentional
  • Management:
  • Safety
  • A,B,C,D,E – correcting as go along
  • Hx – what drug, how much, when taken, how taken, mixed with anything else, collect all suspected drugs to take to A&E, any treatment occurred yet
  • Administer high flow O2 if working alone or as double ECA crew; administer according to clinician’s guidance
19
Q

Some common drugs used in poisoning / overdoses

A
  • Paracetamol
  • Aspirin
  • Tricyclic antidepressants – amitriptyline, dothiepin
  • Heroin and other opiates – morphine, pethidine
  • Barbiturates / ‘downers’ – amytal, seconal
  • Amphetamines – speed / ecstasy
  • Alcohol
  • Organo-phosphates – pesticides, insecticides, nerve agents
  • Benzodiazepines – Diazepam, Midazolam
  • Recreational drugs – Cocaine, Cannabis
  • Beta-blockers – Atenolol, Propanolol
  • Legal Highs!! New Psychoactive Substances (NPS)
20
Q

Legal Highs or New Psychoactive substances (NPS)

A

Home office produced pack as part of Drug Misuse and dependency policy, which includes:

  • facts and information about NPS
  • case studies on working with young people who use NPS
  • resources to help start conversations about NPS with young people
  • references for further help and information

https://www.gov.uk/government/publications/new-psychoactive-substances-nps-resource-pack

21
Q

Psychological considerations

A
  • May behave irrationally or unpredictably. Remember safety is paramount. Behave sensitively and tactfully with sympathy or gentle firmness where necessary
  • Some drugs heighten awareness – limit pt’s exposure to excessive light & sound?
  • Remain objective and professional at all times
  • Remain neutral – avoid criticism or judgement – it will not help and may aggravate the situation
22
Q

Important Points

A

Removing contaminated clothing and any contamination of the skin takes priority over everything except immediate life support treatment

Avoid contamination yourself, particularly hands; always wear protective gloves at this type of incident

Clear contaminated equipment before use again

Several of these products produce severe excitable states. Manage patients gently, quietly and with minimum fuss

q

Remember patient requires rapid medical intervention at nearest A&E Dept or specialist Poisons Unit

23
Q

General Management Checklist

A

Safety first – perform dynamic risk assessment

Avoid contaminating yourself

Act quickly, speed is essential

Ensure open airway

Assist ventilation if required (never mouth to mouth)

If unconscious do not induce vomiting

Conscious (if caustic or petroleum products have been swallowed) give milk, water

Do not give salt drinks this will induce vomiting

Save a sample of vomit

Monitor patient for deterioration

Keep patient quiet and don’t allow them to walk

Reassurance

Collect sample of poisons and bottles

24
Q
A
25
Q
A
26
Q

Drug abuse

A

•Use of any substance that causes –

  • Physical
  • Psychological
  • Economic
  • Legal
  • Social……………..harm
27
Q

Physical dependence

A
  • Physical adaptation to the drug
  • Tolerance
  • Withdrawal symptoms when removed
  • Emotion state
  • Craving
  • Withdrawal effects feeling of well being
28
Q

Tolerance

A

•Physiological adaptation such that

…………Larger and larger doses required

29
Q

Withdrawal syndrome

A
  • A predictable series of signs & symptoms
  • Largely due to disruption of CNS activity
  • Following abrupt discontinuation
30
Q

Addiction

A

A chronic disorder characterised by

  • Compulsive use of a substance
  • Continued used despite the harm caused
31
Q

Main categories

A
  • Narcotics/ Opiates - (Coca plant - derivatives) Opium, heroin, morphine, codeine etc
  • CNS Depressants - Alcohol, sedatives, tranquilisers, antihistamines, nitrous oxide
  • CNS Stimulants - Cocaine*, ecstasy, amphetamines
  • Hallucinogens - LSD, phencyclidine (PCP)**, ‘Toads’, ‘magic mushrooms’
  • Inhalants - Butane, glue, petrol, nicotine
  • Steroids - Dianabol, nandrolone
  • Cannabis

* Cocaine is dual classified as a narcotic

** PCP is dual classified as a stimulant

32
Q

Narcotics
Ingested, Injected, Inhaled (smoked)

A

General effects

  • Relaxation
  • Euphoria
  • Drowsiness
  • Nausea
  • Sniffles
  • Watery eyes

Nodding

Overdose

  • Pale/ Cyanosed
  • Cool
  • Clammy
  • Respiratory depression/ arrest
  • Tachycardia
  • Constricted pupils
  • Convulsions
  • Coma

Death

33
Q

CNS Depressants
Ingested

A

General effects

  • Relieve anxiety
  • Relieve irritability
  • Sensory alteration
  • Muscle relaxant
  • Impaired judgement
  • Impaired coordination

Loss of appetite

Overdose

  • Pale
  • Cool
  • Clammy
  • Shallow respirations
  • Tachycardia
  • Dilated pupils
  • Coma

Death

34
Q

Hallucinogens
Ingested, Inhaled, Absorbed

A

General effects

Altered perception of

  • Time
  • Smell
  • Touch
  • Taste

Sight

Overdose

  • Convulsions
  • CVA
  • Secondary injury
  • Flashbacks
35
Q

Inhalants
Inhaled (smoked, sniffed)

A

General effects

  • Light headedness
  • Inhalants on clothes, hands, in bag, gas canisters etc
  • Rashes around nose and mouth

Overdose

  • Pale
  • Cool
  • Clammy
  • Loss of muscle control
  • Slurred speech
  • Reduced LOC
  • CVA
  • Coma

Death

36
Q

Steroids
Ingested, Injected

A

General effects

  • Increased strength
  • Increased musculature
  • Severe acne
  • Rashes
  • Stunted growth
  • Masculine traits
  • Aggressiveness
  • Tumours
  • Cancer

Cataracts

Overdose

  • Hallucinations
  • Aggression

37
Q

Cannabis
Ingested, Inhaled

A

General effects

  • Impaired short term memory
  • Shorten attention span
  • Delayed reflexes
  • Euphoria
  • Relaxed inhibitions
  • Lung damage
  • Birth defects
  • Cancer

Overdose

  • Pale
  • Cool
  • Clammy
  • Tachycardia
  • Nausea & vomiting
  • Dehydration

Secondary injury

38
Q

Volatile Substances

  • Adhesives or glues
  • Nail polish/ polish remover
  • Rubber solutions
  • Petrol
  • Dyes
  • Lighter fuel
  • Aerosols
  • Cleaning agents

Fire Extinguishers

A
39
Q

Effects

A
  • Light headedness
  • Euphoria
  • Decrease in anxiety
  • Lessening of inhibition
  • Drowsiness
  • Impaired muscular co-ordination

  • Impaired judgement
  • Nausea
  • Hallucinations
  • Increased or irregular heart rate
  • Headache
  • Pulmonary oedema
40
Q

Risks

A
  • Sudden death
  • Cardio arrhythmia (Irregular heart beat)
  • Choking – vomit or substance
  • Asphyxiation through contraction of the wind pipe (aerosols)
  • Burns - Exposure to flame or chemicals
  • Cancer
  • Poor judgement skills and recklessness
41
Q

Management

A

Management

If the patient is unconscious

  • Ensure ABC’s,
  • High levels of oxygen,
  • Recovery position,
  • Observe vital signs.