mod 6 Flashcards
Ionise atoms
Process where electromagnetic waves interact with and cause atoms to lose or gain electrons.
DNA repair system
Mechanism that corrects changes or damage to the DNA molecule.
Pyrimidine dimmers
Covalent linkages formed between adjacent pyrimidine bases in DNA due to UV light exposure, leading to mutations.
Ethidium bromide
Chemical used in molecular biology to visualize DNA, which can cause frameshift mutations.
Jumping genes
Segments of DNA that can change their position in chromosomal DNA, leading to mutations.
Point Mutations
Mutations that affect one or a few nucleotides within a gene sequence.
Silent mutation
Mutation that has no effect on the encoded amino acid due to genetic code redundancy.
Chromosome mutation
Mutation that changes or affects a long segment of DNA, such as deletion, inversion, translocation, or duplication.
Somatic mutations
Genetic alterations acquired by a cell, usually caused by external mutagens, not passed onto offspring.
Germ-line mutations
Mutations in germ cells (sperm or ovum) that may be passed onto offspring during fertilization.
Coding DNA
DNA sequences that encode for proteins, also known as genes.
Non-coding DNA
DNA sequences that do not encode for proteins, making up the majority of the human genome.
Exons
Coding segments of DNA involved in gene expression, making it into the final mRNA.
Introns
Non-coding segments of DNA that are usually not translated, but can affect gene expression if mutated.
Fertilisation
Process where two gametes come together to form a zygote, restoring the full set of chromosomes and causing genetic variation.
Meiosis
Cell division process that produces gametes, leading to genetic variation through mutation, crossing-over, and non-disjunction.
Non-disjunction
Failure of homologous chromosomes to separate during cell division, leading to abnormal chromosome numbers in daughter cells
Mutation
Changes in DNA sequence that can be caused by various factors such as EMR sources, chemicals, naturally occurring mutagens, point mutations, and chromosomal mutations
Gene pool
The total genetic diversity found within a population, influenced by processes like mutation, gene flow, and genetic drift
Gene flow
The transfer of genetic variation (different alleles) from one population to another through migration of individuals, leading to changes in allele frequency and genetic diversity
Genetic drift
Changes in allele frequency within a population due to random events, such as bottlenecking and the founder effect, which can lead to loss of genetic variation
Bottlenecking
A sharp reduction in the size of a population due to a catastrophic event, leading to a decrease in genetic diversity
Founder effect
The reduced genetic diversity that results when a population is descended from a small number of colonizing ancestors
Recombinant DNA
DNA formed by combining genetic material from multiple sources, often achieved through the use of plasmids as carriers for foreign DNA
Transgenic animals
Animals that have had foreign genes inserted into their genome, often for the purpose of producing specific proteins or pharmaceuticals
Xenotransplantation
The transplantation of organs or tissues from one species to another, often involving genetically modified animals as organ donors