MOD 2 Flashcards

(94 cards)

1
Q

Which of the following needs bile for absorption?
A. Retinol
В. Ascorbic acid
C. Biotin
D. Folic acid

A

A. Retinol

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2
Q

Young twigs of Querus Infectoria can be used to extract hydrolysable tannins like gallic and ellagic acid. It occurs when Cynips Tinctoria burrows a hole into a twig to lay its eggs.
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D. Both statements are incorrect

A

D. Both statements are incorrect

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3
Q

Which of the following triads is
correct?
A. Arbutin - Uva-ursi - Diuretic (Phenol glycolide)
B. Oenothera biennis - Evening
Primrose - (Analgesic)
C. Glycyrrhizic acid - Licorice -
Antidiabetic)
D. Morphine - Opium -(Anesthetic),
Analgene

A

A. Arbutin - Uva-ursi - Diuretic (Phenol glycolide)

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4
Q

Which of the following tannin
constituent will not decolorize potassium permanganate?
A. Pyrogallol
B. Gallic acid
C. Ellagic acid
D. Cyanidin

A

D. Cyanidin

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5
Q

Which of the following tannin
constituent will give blue-black color in FeCla
A. Catechin
B. Phlobaphene
C. Leucocyanidins
D. Geraniin

A

D. Geraniin

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6
Q

Which of the following statements
is/are true?
A. Deoxy xylulose 5-Phosphate pathway (DOXP), sometimes referred to as Methylerythritol 4-Phosphate pathway (MEP), is an alternative cytosolic biosynthetic pathway for isopentenyl pyrophosphate and dimethyl allyl pyrophosphate
B. The rate limiting enzyme of MEP is DOXP
C. The mevalonate path nway is present in mammalian systems and, as a result, is a relevant pharmacological target for modulating lipid biosynthesis.
D. A and C
E. AOTA

A

C. The mevalonate path nway is present in mammalian systems and, as a result, is a relevant pharmacological target for modulating lipid biosynthesis.

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7
Q

Which of the following statements
is/are correct?
I. Saponification value is the number of mg of KOH needed to saponify esters in 1 g of the samplel
II. Ester value is the number of mg of KOH required to neutralize the free acids and saponify the esters contained in 1 g of the sample
III. Acetyl value is the number of mg of KOH required to neutralize the acetic acid freed by the hydrolysis of acetylated sample
IV. Hydroxyl value is the number of mg KOH required to neutralize the acid combined by acylation of the sample and to hydrolyze the esters in 1g of the sample
A. I, II, III, IV
B, II, III, IV
C. I, II
D. III, IV

A

D. III, IV

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8
Q

Which of the following proteins
perform structural functions?
A. Immunoglobulins
B. Albumin
C. Keratin
D. Myosin

A

C. Keratin

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9
Q

Which of the following pairs is/are
correctly matched?
A. Flavonoid: arbutin Then glycogide
B. Aldehyde: quercitrin Have noid
C. Saponin: vanillin Aldehyde
D. Phenol: diosgenin Saponin
E. NOTA

A

E. NOTA

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10
Q

Which of the following best
represents a monosaccharide?
A. C2H6O
B. C4H8O4
С.Н606
D. C6H8O7

A

B. C4H8O4

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11
Q

Which of the following histological
layer of adrenal gland produces
mineralocorticoids?
A. Adrenal medulla B. Zona reticularis
C. Zona fasciculata
D. Zona glomerulosa

A

D. Zona glomerulosa

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12
Q

Which of the following cofactors is
needed to drive off the carboxylation of
pyruvate to oxaloacetate?
A. PLP
B. THF
C. FAD
D. H

A

D. H

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13
Q

Which of the following is/are
classified as non-saponifiable lipids?
I. Stigmasterol
II. Linolenic acid
III. Palmitic acid
IV. Limonene
A. I
В. I, IV
C. II, III
D. II, III, IV

A

В. I, IV

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14
Q

Which of the following are correctly
matched with their therapeutic use?
A. Momordica charantia -antidyslipidemia
B. Cassia alata - antifungal
C. Blumea balsamifera - anthelminthic
D. Carmona retusa - diuretic

A

B. Cassia alata - antifungal

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15
Q

Which of the following amino acids
is the most acidic?
A. Arg (aka, = 2.07, pka, = 9.04, pKas = 12.48)
B. Giu (pKa: = 2.10, pKaz = 9.47, pKas =4.07)
C.Asp (pKa: = 2.10, pKa. = 9.82, pKas =3.86)
D His (pKa: = 1.77, pKaz = 9.18, pKas =16.10)
E. C & D

A

E. C & D

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16
Q

Which of the following alkaloids
possess cholinergic effects?
A. Atropine
В. Pilocarpine
C. Hyoscyamine
D. Hyoscine

A

В. Pilocarpine

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17
Q

What is the most active form of
vitamin D that is synthesized in the
kidneys through hydroxylation reaction?
A. Ergocalciferol Di
B. Cholecalciferol Ds
C. 1.25 - dihydroxycholecalciferol -
culutre)
D. 25 - hydroxycholecalciferol

A

C. 1.25 - dihydroxycholecalciferol -
culutre)

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18
Q

What is the enzyme needed by the
salvage pathway for the synthesis of ribose-5-phosphate, a component of nucleotides?
A. Nucleotide kinases:
B. Nucleotide synthase
C. Phosphoribosyl transferases
D. Ribonucleotide reductase

A

C. Phosphoribosyl transferases

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19
Q

Water and steam distillation is the
appropriate method to obtain volatile extracts when the sample is?
A. Dried, not subjected to injury
B. Dried or fresh, may be injured by
boiling
C. Fresh
D. Cannot be distilled without
decomposition

A

B. Dried or fresh, may be injured by
boiling

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20
Q

W is an amino acid with diverse
physiological functions both in plant and mammalian systems. Which of the following metabolic intermediates commits the shikimic pathway to W synthesis?
A. Chorismate
B. Anthranilate
C. Prephenate
D. Phenyl pyruvate

A

A. Chorismate

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21
Q

Vitamin F
A. Linoleic, a-linolenic
B. Linoleic, y-linolenic
C. Oleic, a-linolenic
D. Oleic, y-linolenic

A

A. Linoleic, a-linolenic

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22
Q

Used as a macerating fluid to extract chlorophyll in guava leaves
A. Acetone
B. Acetic acid - soloniac
C. Hot benzene - Chrysander
D. Hexane fats

A

A. Acetone

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23
Q

Used as a disinfectant in Dewitts
toothache drope
A. Creosol
B. Cadinene
C. Eugenol
D. Thymol

A

A. Creosol

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24
Q

Test hydroxylase is the enzyme
needed n melanin biosynthesis. Lack of melanin can cause pigmentation diseases such as vitiligo or albinism.
A. The first statement is correct while the second statement is incorrect
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D Both statements are incorrect

A

B. The first statement is incorrect while the second statement is correct.

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25
Transformation of pyruvate to acetaldehyde s catalyzed by? A. Pyruvate decarboxylase B. Pyruvate carboxylase C. Pyruvate dehydrogenase D. Pyruvate kinase
A. Pyruvate decarboxylase
26
This refers to cofactor that is firmly bound to an apoenzyme А. Zymogen B. Holaenzyme C. Prosthetic group D. Second substrate
C. Prosthetic group
27
This plant species is well-known to constitute this phenol glycoside eliciting delayed hypersensitivity reaction. A. Alexandria senna B. Salix fragilis C. Rhus radicans D. Rhamnus purshianus
C. Rhus radicans
28
This is considered as the best source of steroidal hormones А. Mexican cruz vanilla B. Mexican Yam C. American hellebore D. European hellebore
B. Mexican Yam
29
This German medical student coined the term “pharmacognosy in Analecta Pharmacognostica in 1815 A. Seydler B. Schmidt C. Galen D. Fluckiger
A. Seydler
30
This constituent of mayapple exnibits antimitetic property which is valuable for cancer chemotherapy A. Podophyllotoxin B. Podophyllin C. a-peltatin D. a-resin
A. Podophyllotoxin
31
The resulting product of reduction of TAG from VLDL is a cholesterol- dominant product called A. HDL B. LDL C. VLDL D. Chylomicrons
B. LDL
32
The region in a RNA transcript that is being spliced away is called? A. Exons B. Introns C. Anticodon D. Codon
B. Introns
33
The reagent used in Seliwanoff test is? A.Resorcinol B. Orcinol Dials C. Phenyihydrazine ortne test D. Sulfuric acid Lebermann-buretard
A.Resorcinol
34
The rate limiting enzyme in Kreb&s cycle is? A. Succinate-dehydrogenase B. NADH-dehydrogenase C. Isocitrate dehydrogenase D. a-ketoglutarate dehydrogenase
C. Isocitrate dehydrogenase
35
35. The rate limiting enzyme in glycogen breakdown is? A. Glycogen hydrolase B. Glycogen dehydrogenase C. Glycogen phosphorylase D. Glycogen synthase
C. Glycogen phosphorylase
36
The oxidizing agent present in Hubls solution A. H2O2 B. I2 C. K2Cr2O7 D. KMnO4
B. I2
37
A major constituents of eucalyptus chemically classified as? A. Oxide B. Phenolic ether C. Phenol D. Alcohol
A. Oxide
38
The following is/are incorrect except I. Hydrolysable in bromine solution: no ppt II. non-hydrolysable in bromine solution: precipitate III. Hydrolysable in gold beaters test: bloom leather IV. non-hydrolysable in gold beaters test: tanners red A. III. IV B. II, III C. I, II, IV D. I, II, III, IV
D. I, II, III, IV
39
The following are true alkaloids except? A. Nicotine B. Atropine C. Morphine D. Caffeine
D. Caffeine
40
The following are stereoptenes EXCEPT A. Methylsalicylate B. Anethole C. Thymol D. Menthol
A. Methylsalicylate
41
41. The following amino acids is/are exogenously obtained by humans I. F I I. P III. Y IV. T A. I, III B. II, III C. I, IV D. II, IV
C. I, IV
42
The elongation process of the RNA strand proceeds a unidirectional fashion. A. The first statement is correct while the second statement is incorrect. B. The first statement is incorrect while the second statement is correct C. Both statements are correct D. Both statements are incorrect
A. The first statement is correct while the second statement is incorrect.
43
RNA Is an example of? A. Oxidation B. Reduction C. Hydrolysis D. Hydrogenation
A. Oxidation
44
The chemical constituent of juniper oil is classified as? A. Oxide B. Phenolic ether C. Phenol D. Alcohol
D. Alcohol
45
Test for 2-deoxy sugar A. Keller-Killiani - B. Liebermann-Burchard C. Willstatter-Cyanidin D. Guignard
A. Keller-Killiani -
46
Spearmint oil mainly constitutes? A. Menthol B. Diosphenol C. (-) carvone D. (+) carvone
C. (-) carvone
47
Sinalbin, a constituent of Brassica alba is hydrolyzed to by the action of A. Allyl isothiocyanate B. Acrinyl isothiocyanate C. Prunasin D. Amygdalin
B. Acrinyl isothiocyanate
48
Select the proper orientation of glycosidic bonds existing between the monomeric units of Maltose A. a-1,4 B. a-1,2 C. B-1,4 D. B-2,1
A. a-1,4
49
Select the polysaccharide A. Heparin B. Inulin C. Chitin D. AOTA E. NOTA
A. Heparin
50
Select the end-product of purine metabolism? A. Urea B. Urate C. Ureide D. Allantom
B. Urate
51
Select the end product of reductive glucose metabolism А. Gluconic acid oxidation В. Glucuronic acid C. Glucaric acid D. Glucitol
D. Glucitol
52
Select the amino acid that may undergo glucose and ketone metabolism A. Leucine B. Isoleucine C. Glutamine D. Glutamate
B. Isoleucine
53
Select the acidic amino acid A. Glycine B. Glutamine C. Glutamate D. Guanine
C. Glutamate
54
Saponin glycosides can be classified based on their sapogenins. The chemical property of saponin glycoside with triterpenoid aglycone is? A. Acidic B. Basic C. Neutral D. Achiral
A. Acidic
55
Production of ATP is expected to be most impaired with addition of this compound in mitochondrial sample А. Antimycin A B. Azide C. Dinitrophenol (DNP) D. CN
C. Dinitrophenol (DNP)
56
Plant containing solanaceous alkaloid? A. European mandrake B. American mandrake C. Black Indian hemp D. Indian hemp
A. European mandrake
57
Pick the descriptor that correctly identifies dextrin A. Formed by many microorganisms including Leuconostoc mesenteroides B. A byproduet of incomplete starch hydrolysis cause by alpha amylase
C. Used as plasma expander D. Commercially available as 10% solution
B. A byproduet of incomplete starch hydrolysis cause by alpha amylase
58
59
Pathological product from the stomach of Physeter macrocephalus A. Ambergris B. Spermaceti C. Civetone D. Muscone
A. Ambergris
60
Paclitaxel is isolated from two plant species namely. Pacific yew (Taxus baccata) and Periwinkle (Catharanthus roseus). The mechanism of action of this antineoplastic alkaloidal ester is by promoting microtubule disassembly. A. The first statement is correct while the second statement is incorrect B. The first statement is incorrect while the second statement is correct. C. Both statements are correct D. Both statements are incorrect
D. Both statements are incorrect
61
Oil from this plant seed contains a principle that was tested for sterility in men but failed after recent multiple clinical trials A. Ricinus communi B. Arachis hypogea C. Glycine soja D. Gossypium hirsutum
D. Gossypium hirsutum
62
Makes up majority of starch chemical framework A. Amylose B. Amylopectin C. Amylase D. Cellulose
B. Amylopectin
63
Level of protein organization present in hemoglobin? А. Primary В. Secondary C. Tertiary D. Quaternary
D. Quaternary
64
In glucose catabolism, which of the following intermediates undergoes aldol-cleavage? A. Glyceraldehyde 3- phosphate - B. Fructose 1,6-bisphosphate C. 2,3 - bisphosphoglycerate D. 1,3-bisphosphoglycerate
B. Fructose 1,6-bisphosphate
65
Green hellebore contains cardiac glycoside that induces cardiac depression: On the other hand, black hellebore comprises a steroidal alkaloid that induces cardiac stimulation A. The first statement is correct while the second statement is incorrect. B. The first statement is incorrect while the second statement is correct C. Both statements are correct. D. Both statements are incorrect
D. Both statements are incorrect
66
Find the statement consistent with the structural description of sugars. A. Vertical bonds in a Fischer projection correspond to bonds directed behind the paper, horizontal bonds correspond to bonds oriented in front. B. The cyclic forms of represented by the wher projection best C A group that is written to the right of the carbon in a Fischer projection has an downward orientation in a Haworth projection D. All of the above
A. Vertical bonds in a Fischer projection correspond to bonds directed behind the paper, horizontal bonds correspond to bonds oriented in front.
66
For ethanol to be produced during fermentation, pyruvate decarboxylase requires vitamin B7 as a coenzyme. Such enzyme converts pyruvate to oxaloacetate. A. The first statement is correct while the second statement is incorrect. B. The first statement is incorrect while the second statement is correct. C. Both statements are correct. D. Both statements are incorrect
D. Both statements are incorrect
66
Find the structural features consistent with nucleotides A. Sugar, phosphate B. Phosphate, sugar, nitrogenous base C. Nitrogenous base, sugar D. Nitrogenous base, phosphate
B. Phosphate, sugar, nitrogenous base
67
Find the ketone bodies I. Acetoacetate II. Acetone III. Beta-hydroxybutyrate IV. Acetele. A. I, III B. I, II, IV C. I, II, III D I. II, III, IV
C. I, II, III
68
Find one of the enzymes that releases carbon dioxide during Krebs cycle A. Isocitrate dehydrogenase B. Succinyl CoA synthetase C. Succinate dehydrogenase D. Malate dehydrogenase
A. Isocitrate dehydrogenase
69
Fetid gum is isolated from? A. Anogeissus latifolia B. Astragalus gummifer C. Sterculia urens D. Acacia senegal
C. Sterculia urens
70
Farber disease is associated deficiency. Fabry is associated with ceramidase with a- Galactosidase deficiency. A. The first statement is correct while the second statement is incorrect. B. The first statement is incorrect while the second statement is correct. C. Both statements are correct. D. Both statements are incorrect
C. Both statements are correct.
71
During blood analysis, the patients blood sample appears to be cherry-red in color. What complex of the electron transport chain is targeted by this unknown poison? A. Complex I В. Complex II C. Complex III D. Complex IV
D. Complex IV
72
Digoxin is best isolated from? A. Foxglove B. Digitalis purpurea C. Digitalis lanata D. A and B E. A and C
C. Digitalis lanata
73
Determine the enzyme commission number (EC) of enzymes that prevent DNA breakage during replication A. EC 5 B. EC 2 C. EC 4 D. EC 6 1 E. EC 1
A. EC 5
74
Decreased insulin level promotes I. Glycolysis Il. Glycogenolysis III Gluconeogenesis IV. Ketogenesis gluegen A. II, III, IV B. II, II, III C. I, II IV D. I, II, III, IV
A. II, III, IV
75
Cytochrome C axidase is another name for complex I|l in the electron transport chain. Complex IV, on the other hand, is cytochrome C reduciase A. The first statement is correct while the second statement is incorrect. B. The first statement is incorrect while the second statement is correct. C. Both statements are correct. D. Both statements are incorrect
D. Both statements are incorrect
76
Clinically useful glycosaminoglycan which serves as anticoagulant in clotting disorders. A. Heparan B. Heparin C. Keratin D. Keratan
B. Heparin
77
Classify tubocurarine A. Quinoline B. Isoquinoline C. Purine D. Pyridine-piperidine
B. Isoquinoline
78
Classify papaverine A. Quinoline B. Isoquinoline C. Purine D. Pyridine-piperidine
B. Isoquinoline
79
Classify glycyrrhizic acid based to its terpenoid backbone A. Hemiterpene B. Sesquiterpene C. Sesterterpene D. Triterpene
D. Triterpene
80
Classify arabinose A. Biose B. Triose C. Tetrose D. Pentose
D. Pentose
81
Choose the terpenoid consisting of three isoprene units A. Hemiterpene B. Sesquiterpene C. Sesterterpene D. Triterpene
B. Sesquiterpene
82
Choose the official identification test for cottonseed oil A. Halphen and Bevan B. Serger C. Million D. Baudoin
A. Halphen and Bevan
83
Choose the characteristics of glycogen I. Homopolymer of glucose Il. More branched than amylopectin III. Storage form of carbohydrate in animals IV. Tests positive in lodine A. I, II B. I, II, III C. I, III, IV D. I, II, III, IV
D. I, II, III, IV
84
Carageenans thickening principle/s is? А. ^ - carageenan B. k - carageenan C. I - caradeenan D. B and C E. AOTA
А. ^ - carageenan
85
Arachidonic acid is released from membrane lipids by platelet-activating factor (PAF). Which of the following enzymes is likely to be in charge of its release for further metabolism? A. Lipoxygenase B. Phospholipase C C. Phospholipase A2 D. Cyclooxygenase
C. Phospholipase A2
86
Anticholinergic alkaloid that can be isolated from Datura metel with anti- motion sickness property A. (-) Hyoscyamine l В. (+) Hyoscyamine C. Hyoscine D. Atropine
В. (+) Hyoscyamine
87
Analyze the mechanism or catalytic strategy exhibited by DNA ligase A. Promotion of a reaction that immeasurably slow at neutral pH B. Attainment of a high degree of specificity C. Utilization of the free energy associated with the hydrolysis of ATP D. Achievement of high absolute rate of reaction that is suitable for integration with other physiological processes
C. Utilization of the free energy associated with the hydrolysis of ATP
88
Amino acid that possess isobutyl side chain A. Isoleucine B. Leucine C. Lysine D. Glycine
B. Leucine
89
Also known as antirachitic vitamin A. Vitamin A B. Vitamin B C. Vitamin C D. Vitamin D
D. Vitamin D
90
All of the following are membrane lipids except? A. Cholesterol B. Phospholipid C. Glycolipid D. Triglycerides
D. Triglycerides
91
Alcohol glycoside A. Vanilla planifolia B. Salix purpurea C. Ginkgo biloba D. Silybum marianum
B. Salix purpurea
92
A resin used to mask the bitter taste of quinine by paralyzing the taste buds a. Mastic b. Jalap C. Licorice D. Eriodictyon
D. Eriodictyon