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RPh 2024! > MOD 2 > Flashcards

MOD 2 Flashcards

1
Q

Which of the following needs bile for absorption?
A. Retinol
В. Ascorbic acid
C. Biotin
D. Folic acid

A

A. Retinol

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2
Q

Young twigs of Querus Infectoria can be used to extract hydrolysable tannins like gallic and ellagic acid. It occurs when Cynips Tinctoria burrows a hole into a twig to lay its eggs.
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D. Both statements are incorrect

A

D. Both statements are incorrect

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3
Q

Which of the following triads is
correct?
A. Arbutin - Uva-ursi - Diuretic (Phenol glycolide)
B. Oenothera biennis - Evening
Primrose - (Analgesic)
C. Glycyrrhizic acid - Licorice -
Antidiabetic)
D. Morphine - Opium -(Anesthetic),
Analgene

A

A. Arbutin - Uva-ursi - Diuretic (Phenol glycolide)

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4
Q

Which of the following tannin
constituent will not decolorize potassium permanganate?
A. Pyrogallol
B. Gallic acid
C. Ellagic acid
D. Cyanidin

A

D. Cyanidin

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5
Q

Which of the following tannin
constituent will give blue-black color in FeCla
A. Catechin
B. Phlobaphene
C. Leucocyanidins
D. Geraniin

A

D. Geraniin

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6
Q

Which of the following statements
is/are true?
A. Deoxy xylulose 5-Phosphate pathway (DOXP), sometimes referred to as Methylerythritol 4-Phosphate pathway (MEP), is an alternative cytosolic biosynthetic pathway for isopentenyl pyrophosphate and dimethyl allyl pyrophosphate
B. The rate limiting enzyme of MEP is DOXP
C. The mevalonate path nway is present in mammalian systems and, as a result, is a relevant pharmacological target for modulating lipid biosynthesis.
D. A and C
E. AOTA

A

C. The mevalonate path nway is present in mammalian systems and, as a result, is a relevant pharmacological target for modulating lipid biosynthesis.

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7
Q

Which of the following statements
is/are correct?
I. Saponification value is the number of mg of KOH needed to saponify esters in 1 g of the samplel
II. Ester value is the number of mg of KOH required to neutralize the free acids and saponify the esters contained in 1 g of the sample
III. Acetyl value is the number of mg of KOH required to neutralize the acetic acid freed by the hydrolysis of acetylated sample
IV. Hydroxyl value is the number of mg KOH required to neutralize the acid combined by acylation of the sample and to hydrolyze the esters in 1g of the sample
A. I, II, III, IV
B, II, III, IV
C. I, II
D. III, IV

A

D. III, IV

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8
Q

Which of the following proteins
perform structural functions?
A. Immunoglobulins
B. Albumin
C. Keratin
D. Myosin

A

C. Keratin

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9
Q

Which of the following pairs is/are
correctly matched?
A. Flavonoid: arbutin Then glycogide
B. Aldehyde: quercitrin Have noid
C. Saponin: vanillin Aldehyde
D. Phenol: diosgenin Saponin
E. NOTA

A

E. NOTA

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10
Q

Which of the following best
represents a monosaccharide?
A. C2H6O
B. C4H8O4
С.Н606
D. C6H8O7

A

B. C4H8O4

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11
Q

Which of the following histological
layer of adrenal gland produces
mineralocorticoids?
A. Adrenal medulla B. Zona reticularis
C. Zona fasciculata
D. Zona glomerulosa

A

D. Zona glomerulosa

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12
Q

Which of the following cofactors is
needed to drive off the carboxylation of
pyruvate to oxaloacetate?
A. PLP
B. THF
C. FAD
D. H

A

D. H

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13
Q

Which of the following is/are
classified as non-saponifiable lipids?
I. Stigmasterol
II. Linolenic acid
III. Palmitic acid
IV. Limonene
A. I
В. I, IV
C. II, III
D. II, III, IV

A

В. I, IV

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14
Q

Which of the following are correctly
matched with their therapeutic use?
A. Momordica charantia -antidyslipidemia
B. Cassia alata - antifungal
C. Blumea balsamifera - anthelminthic
D. Carmona retusa - diuretic

A

B. Cassia alata - antifungal

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15
Q

Which of the following amino acids
is the most acidic?
A. Arg (aka, = 2.07, pka, = 9.04, pKas = 12.48)
B. Giu (pKa: = 2.10, pKaz = 9.47, pKas =4.07)
C.Asp (pKa: = 2.10, pKa. = 9.82, pKas =3.86)
D His (pKa: = 1.77, pKaz = 9.18, pKas =16.10)
E. C & D

A

E. C & D

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16
Q

Which of the following alkaloids
possess cholinergic effects?
A. Atropine
В. Pilocarpine
C. Hyoscyamine
D. Hyoscine

A

В. Pilocarpine

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17
Q

What is the most active form of
vitamin D that is synthesized in the
kidneys through hydroxylation reaction?
A. Ergocalciferol Di
B. Cholecalciferol Ds
C. 1.25 - dihydroxycholecalciferol -
culutre)
D. 25 - hydroxycholecalciferol

A

C. 1.25 - dihydroxycholecalciferol -
culutre)

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18
Q

What is the enzyme needed by the
salvage pathway for the synthesis of ribose-5-phosphate, a component of nucleotides?
A. Nucleotide kinases:
B. Nucleotide synthase
C. Phosphoribosyl transferases
D. Ribonucleotide reductase

A

C. Phosphoribosyl transferases

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19
Q

Water and steam distillation is the
appropriate method to obtain volatile extracts when the sample is?
A. Dried, not subjected to injury
B. Dried or fresh, may be injured by
boiling
C. Fresh
D. Cannot be distilled without
decomposition

A

B. Dried or fresh, may be injured by
boiling

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20
Q

W is an amino acid with diverse
physiological functions both in plant and mammalian systems. Which of the following metabolic intermediates commits the shikimic pathway to W synthesis?
A. Chorismate
B. Anthranilate
C. Prephenate
D. Phenyl pyruvate

A

A. Chorismate

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21
Q

Vitamin F
A. Linoleic, a-linolenic
B. Linoleic, y-linolenic
C. Oleic, a-linolenic
D. Oleic, y-linolenic

A

A. Linoleic, a-linolenic

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22
Q

Used as a macerating fluid to extract chlorophyll in guava leaves
A. Acetone
B. Acetic acid - soloniac
C. Hot benzene - Chrysander
D. Hexane fats

A

A. Acetone

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23
Q

Used as a disinfectant in Dewitts
toothache drope
A. Creosol
B. Cadinene
C. Eugenol
D. Thymol

A

A. Creosol

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24
Q

Test hydroxylase is the enzyme
needed n melanin biosynthesis. Lack of melanin can cause pigmentation diseases such as vitiligo or albinism.
A. The first statement is correct while the second statement is incorrect
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D Both statements are incorrect

A

B. The first statement is incorrect while the second statement is correct.

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25
Q

Transformation of pyruvate to
acetaldehyde s catalyzed by?
A. Pyruvate decarboxylase
B. Pyruvate carboxylase
C. Pyruvate dehydrogenase
D. Pyruvate kinase

A

A. Pyruvate decarboxylase

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26
Q

This refers to cofactor that is firmly
bound to an apoenzyme
А. Zymogen
B. Holaenzyme
C. Prosthetic group
D. Second substrate

A

C. Prosthetic group

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27
Q

This plant species is well-known to
constitute this phenol glycoside eliciting delayed hypersensitivity reaction.
A. Alexandria senna
B. Salix fragilis
C. Rhus radicans
D. Rhamnus purshianus

A

C. Rhus radicans

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28
Q

This is considered as the best
source of steroidal hormones
А. Mexican cruz vanilla
B. Mexican Yam
C. American hellebore
D. European hellebore

A

B. Mexican Yam

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29
Q

This German medical student coined the term “pharmacognosy in Analecta Pharmacognostica in 1815
A. Seydler
B. Schmidt
C. Galen
D. Fluckiger

A

A. Seydler

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30
Q

This constituent of mayapple
exnibits antimitetic property which is valuable for cancer chemotherapy
A. Podophyllotoxin
B. Podophyllin
C. a-peltatin
D. a-resin

A

A. Podophyllotoxin

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31
Q

The resulting product of reduction of TAG from VLDL is a cholesterol-
dominant product called
A. HDL
B. LDL
C. VLDL
D. Chylomicrons

A

B. LDL

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32
Q

The region in a RNA transcript that
is being spliced away is called?
A. Exons
B. Introns
C. Anticodon
D. Codon

A

B. Introns

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33
Q

The reagent used in Seliwanoff test
is?
A.Resorcinol
B. Orcinol Dials
C. Phenyihydrazine ortne test
D. Sulfuric acid Lebermann-buretard

A

A.Resorcinol

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34
Q

The rate limiting enzyme in Kreb&s
cycle is?
A. Succinate-dehydrogenase
B. NADH-dehydrogenase
C. Isocitrate dehydrogenase
D. a-ketoglutarate dehydrogenase

A

C. Isocitrate dehydrogenase

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35
Q
  1. The rate limiting enzyme in glycogen breakdown is?
    A. Glycogen hydrolase
    B. Glycogen dehydrogenase
    C. Glycogen phosphorylase
    D. Glycogen synthase
A

C. Glycogen phosphorylase

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36
Q

The oxidizing agent present in Hubls solution
A. H2O2
B. I2
C. K2Cr2O7
D. KMnO4

A

B. I2

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37
Q

A major constituents of eucalyptus
chemically classified as?
A. Oxide
B. Phenolic ether
C. Phenol
D. Alcohol

A

A. Oxide

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38
Q

The following is/are incorrect except
I. Hydrolysable in bromine solution: no ppt
II. non-hydrolysable in bromine solution: precipitate
III. Hydrolysable in gold beaters test: bloom leather
IV. non-hydrolysable in gold beaters
test: tanners red
A. III. IV
B. II, III
C. I, II, IV
D. I, II, III, IV

A

D. I, II, III, IV

39
Q

The following are true alkaloids
except?
A. Nicotine
B. Atropine
C. Morphine
D. Caffeine

A

D. Caffeine

40
Q

The following are stereoptenes
EXCEPT
A. Methylsalicylate
B. Anethole
C. Thymol
D. Menthol

A

A. Methylsalicylate

41
Q
  1. The following amino acids is/are
    exogenously obtained by humans
    I. F I
    I. P
    III. Y
    IV. T

A. I, III
B. II, III
C. I, IV
D. II, IV

A

C. I, IV

42
Q

The elongation process of the RNA
strand proceeds a unidirectional fashion.
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct
C. Both statements are correct
D. Both statements are incorrect

A

A. The first statement is correct while the second statement is incorrect.

43
Q

RNA Is an example of?
A. Oxidation
B. Reduction
C. Hydrolysis
D. Hydrogenation

A

A. Oxidation

44
Q

The chemical constituent of juniper
oil is classified as?
A. Oxide
B. Phenolic ether
C. Phenol
D. Alcohol

A

D. Alcohol

45
Q

Test for 2-deoxy sugar
A. Keller-Killiani -
B. Liebermann-Burchard
C. Willstatter-Cyanidin
D. Guignard

A

A. Keller-Killiani -

46
Q

Spearmint oil mainly constitutes?
A. Menthol
B. Diosphenol
C. (-) carvone
D. (+) carvone

A

C. (-) carvone

47
Q

Sinalbin, a constituent of Brassica
alba is hydrolyzed to by the action of
A. Allyl isothiocyanate
B. Acrinyl isothiocyanate
C. Prunasin
D. Amygdalin

A

B. Acrinyl isothiocyanate

48
Q

Select the proper orientation of
glycosidic bonds existing between the monomeric units of Maltose
A. a-1,4
B. a-1,2
C. B-1,4
D. B-2,1

A

A. a-1,4

49
Q

Select the polysaccharide
A. Heparin
B. Inulin
C. Chitin
D. AOTA
E. NOTA

A

A. Heparin

50
Q

Select the end-product of purine
metabolism?
A. Urea
B. Urate
C. Ureide
D. Allantom

A

B. Urate

51
Q

Select the end product of reductive
glucose metabolism
А. Gluconic acid oxidation
В. Glucuronic acid
C. Glucaric acid
D. Glucitol

A

D. Glucitol

52
Q

Select the amino acid that may
undergo glucose and ketone
metabolism
A. Leucine
B. Isoleucine
C. Glutamine
D. Glutamate

A

B. Isoleucine

53
Q

Select the acidic amino acid
A. Glycine
B. Glutamine
C. Glutamate
D. Guanine

A

C. Glutamate

54
Q

Saponin glycosides can be classified
based on their sapogenins. The
chemical property of saponin glycoside with triterpenoid aglycone is?
A. Acidic
B. Basic
C. Neutral
D. Achiral

A

A. Acidic

55
Q

Production of ATP is expected to be
most impaired with addition of this
compound in mitochondrial sample
А. Antimycin A
B. Azide
C. Dinitrophenol (DNP)
D. CN

A

C. Dinitrophenol (DNP)

56
Q

Plant containing solanaceous
alkaloid?
A. European mandrake
B. American mandrake
C. Black Indian hemp
D. Indian hemp

A

A. European mandrake

57
Q

Pick the descriptor that correctly
identifies dextrin
A. Formed by many microorganisms
including Leuconostoc mesenteroides
B. A byproduet of incomplete starch
hydrolysis cause by alpha amylase
C. Used as plasma expander
D. Commercially available as 10%
solution

A

B. A byproduet of incomplete starch
hydrolysis cause by alpha amylase

58
Q
A
59
Q

Pathological product from the
stomach of Physeter macrocephalus
A. Ambergris
B. Spermaceti
C. Civetone
D. Muscone

A

A. Ambergris

60
Q

Paclitaxel is isolated from two plant
species namely. Pacific yew (Taxus
baccata) and Periwinkle (Catharanthus roseus). The mechanism of action of this antineoplastic alkaloidal ester is by promoting microtubule disassembly.
A. The first statement is correct while the second statement is incorrect
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct
D. Both statements are incorrect

A

D. Both statements are incorrect

61
Q

Oil from this plant seed contains a
principle that was tested for sterility in men but failed after recent multiple clinical trials
A. Ricinus communi
B. Arachis hypogea
C. Glycine soja
D. Gossypium hirsutum

A

D. Gossypium hirsutum

62
Q

Makes up majority of starch
chemical framework
A. Amylose
B. Amylopectin
C. Amylase
D. Cellulose

A

B. Amylopectin

63
Q

Level of protein organization present in hemoglobin?
А. Primary
В. Secondary
C. Tertiary
D. Quaternary

A

D. Quaternary

64
Q

In glucose catabolism, which of the
following intermediates undergoes aldol-cleavage?
A. Glyceraldehyde 3- phosphate -
B. Fructose 1,6-bisphosphate
C. 2,3 - bisphosphoglycerate
D. 1,3-bisphosphoglycerate

A

B. Fructose 1,6-bisphosphate

65
Q

Green hellebore contains cardiac
glycoside that induces cardiac
depression: On the other hand, black hellebore comprises a steroidal alkaloid that induces cardiac stimulation
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct
C. Both statements are correct.
D. Both statements are incorrect

A

D. Both statements are incorrect

66
Q

Find the statement consistent with
the structural description of sugars.

A. Vertical bonds in a Fischer projection correspond to bonds directed behind the paper, horizontal bonds correspond to bonds oriented in front.

B. The cyclic forms of represented by the wher projection best

C A group that is written to the right of the carbon in a Fischer projection has an downward orientation in a Haworth projection

D. All of the above

A

A. Vertical bonds in a Fischer projection correspond to bonds directed behind the paper, horizontal bonds correspond to bonds oriented in front.

66
Q

For ethanol to be produced during
fermentation, pyruvate decarboxylase requires vitamin B7 as a coenzyme. Such enzyme converts pyruvate to oxaloacetate.
A. The first statement is correct while
the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D. Both statements are incorrect

A

D. Both statements are incorrect

66
Q

Find the structural features
consistent with nucleotides
A. Sugar, phosphate
B. Phosphate, sugar, nitrogenous base
C. Nitrogenous base, sugar
D. Nitrogenous base, phosphate

A

B. Phosphate, sugar, nitrogenous base

67
Q

Find the ketone bodies
I. Acetoacetate
II. Acetone
III. Beta-hydroxybutyrate
IV. Acetele.

A. I, III
B. I, II, IV
C. I, II, III
D I. II, III, IV

A

C. I, II, III

68
Q

Find one of the enzymes that
releases carbon dioxide during Krebs cycle
A. Isocitrate dehydrogenase
B. Succinyl CoA synthetase
C. Succinate dehydrogenase
D. Malate dehydrogenase

A

A. Isocitrate dehydrogenase

69
Q

Fetid gum is isolated from?
A. Anogeissus latifolia
B. Astragalus gummifer
C. Sterculia urens
D. Acacia senegal

A

C. Sterculia urens

70
Q

Farber disease is associated
deficiency. Fabry is associated with ceramidase with a- Galactosidase deficiency.
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D. Both statements are incorrect

A

C. Both statements are correct.

71
Q

During blood analysis, the patients
blood sample appears to be cherry-red in color. What complex of the electron transport chain is targeted by this unknown poison?
A. Complex I
В. Complex II
C. Complex III
D. Complex IV

A

D. Complex IV

72
Q

Digoxin is best isolated from?
A. Foxglove
B. Digitalis purpurea
C. Digitalis lanata
D. A and B
E. A and C

A

C. Digitalis lanata

73
Q

Determine the enzyme commission
number (EC) of enzymes that prevent DNA breakage during replication
A. EC 5
B. EC 2
C. EC 4
D. EC 6 1
E. EC 1

A

A. EC 5

74
Q

Decreased insulin level promotes
I. Glycolysis
Il. Glycogenolysis
III Gluconeogenesis
IV. Ketogenesis gluegen

A. II, III, IV
B. II, II, III
C. I, II IV
D. I, II, III, IV

A

A. II, III, IV

75
Q

Cytochrome C axidase is another
name for complex I|l in the electron
transport chain. Complex IV, on the
other hand, is cytochrome C reduciase
A. The first statement is correct while the second statement is incorrect.
B. The first statement is incorrect while the second statement is correct.
C. Both statements are correct.
D. Both statements are incorrect

A

D. Both statements are incorrect

76
Q

Clinically useful glycosaminoglycan
which serves as anticoagulant in clotting
disorders.
A. Heparan
B. Heparin
C. Keratin
D. Keratan

A

B. Heparin

77
Q

Classify tubocurarine
A. Quinoline
B. Isoquinoline
C. Purine
D. Pyridine-piperidine

A

B. Isoquinoline

78
Q

Classify papaverine
A. Quinoline
B. Isoquinoline
C. Purine
D. Pyridine-piperidine

A

B. Isoquinoline

79
Q

Classify glycyrrhizic acid based to its
terpenoid backbone
A. Hemiterpene
B. Sesquiterpene
C. Sesterterpene
D. Triterpene

A

D. Triterpene

80
Q

Classify arabinose
A. Biose
B. Triose
C. Tetrose
D. Pentose

A

D. Pentose

81
Q

Choose the terpenoid consisting of
three isoprene units
A. Hemiterpene
B. Sesquiterpene
C. Sesterterpene
D. Triterpene

A

B. Sesquiterpene

82
Q

Choose the official identification test for cottonseed oil
A. Halphen and Bevan
B. Serger
C. Million
D. Baudoin

A

A. Halphen and Bevan

83
Q

Choose the characteristics of
glycogen
I. Homopolymer of glucose
Il. More branched than amylopectin
III. Storage form of carbohydrate in
animals
IV. Tests positive in lodine

A. I, II
B. I, II, III
C. I, III, IV
D. I, II, III, IV

A

D. I, II, III, IV

84
Q

Carageenans thickening principle/s
is?
А. ^ - carageenan
B. k - carageenan
C. I - caradeenan
D. B and C
E. AOTA

A

А. ^ - carageenan

85
Q

Arachidonic acid is released from
membrane lipids by platelet-activating factor (PAF). Which of the following enzymes is likely to be in charge of its release for further metabolism?
A. Lipoxygenase
B. Phospholipase C
C. Phospholipase A2
D. Cyclooxygenase

A

C. Phospholipase A2

86
Q

Anticholinergic alkaloid that can be
isolated from Datura metel with anti- motion sickness property
A. (-) Hyoscyamine l
В. (+) Hyoscyamine
C. Hyoscine
D. Atropine

A

В. (+) Hyoscyamine

87
Q

Analyze the mechanism or catalytic
strategy exhibited by DNA ligase
A. Promotion of a reaction that
immeasurably slow at neutral pH
B. Attainment of a high degree of
specificity
C. Utilization of the free energy
associated with the hydrolysis of ATP
D. Achievement of high absolute rate of reaction that is suitable for integration with other physiological processes

A

C. Utilization of the free energy
associated with the hydrolysis of ATP

88
Q

Amino acid that possess isobutyl
side chain
A. Isoleucine
B. Leucine
C. Lysine
D. Glycine

A

B. Leucine

89
Q

Also known as antirachitic vitamin
A. Vitamin A
B. Vitamin B
C. Vitamin C
D. Vitamin D

A

D. Vitamin D

90
Q

All of the following are membrane
lipids except?
A. Cholesterol
B. Phospholipid
C. Glycolipid
D. Triglycerides

A

D. Triglycerides

91
Q

Alcohol glycoside
A. Vanilla planifolia
B. Salix purpurea
C. Ginkgo biloba
D. Silybum marianum

A

B. Salix purpurea

92
Q

A resin used to mask the bitter
taste of quinine by paralyzing the taste buds
a. Mastic
b. Jalap
C. Licorice
D. Eriodictyon

A

D. Eriodictyon

RPh 2024! (5 decks)

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