MOD 1 Flashcards by Andrea Julie

The structure given below represents the common structure of which group of drugs?
a. Benzodiazepines
b. Barbiturates
c. Phenothiazines
d. SSRIs
e. MAO-inhibitors

b. Barbiturates

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Which of the following is/are true
regarding methylation?
I. Generally leads to less polar or water-soluble metabolites
II. Important in the biosynthesis of many endogenous compounds like
epinephrine and melatonin
III. Constitutes only a minor pathway for conjugating drugs or xenobiotic
a. I only
b. I, II, III
C. I, II
d. I, III
e. II, III

e. II, III

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The process involved in the
biotransformation of amitriptyline to nortriptyline.
a. Ketone reduction
b. Ester hydrolysis
c. Epoxidation
d. Aromatic hydroxylation
e. N- demethylation

e. N- demethylation

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Generally accepted other names of
Alcohol, USP
I. Ethanol
II. Wood alcohol / Methanol
III. Spiritus vini rectificatus
IV. Wine spirit
a. I, IV
b. I, II, III
c. I, III, IV
d. I, III
e. I only

c. I, III, IV

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The antibiotic that binds with
ribosome 30s subunit
a. Chloramphenicol
b. Tetracycline
C. Erythromycin
d. Lincomycins
e. Penicillins

b. Tetracycline

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Macrolide antibiotics have these
common characteristics:
I. Large lactone ring
II. Ketone group
Ill. A glycosidic ally linked amino sugar
IV. A symmetric carbon atoms in the
acylamido propanediol chain
a. I only
b. II only
c. I, II, III
d. II, III

c. I, II, III

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Analogue of podophyllotoxin that is
an inhibitor of topoisomerase Il which contains methyl as its R group
a. Vindoline
b. Etoposide
c. Vincristine
d. Epipodophyllotoxin
e. Daunorubicin

b. Etoposide

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Drowsiness is a side effect of
antihistamines that is most common to the
a. Ethylenediamines
b. Tertiary aminoalkyl ethers
C. Phenothiazines
d. H2-receptor antagonists
e. Cimetidine

b. Tertiary aminoalkyl ethers

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Diagonally related pairs of elements
in the periodic table is known as:
a. Metalloids
b. Bridge elements
C. Representative elements
d. Lanthanide series

b. Bridge elements

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The drug most effective against
malarial parasites in the liver but not effective against parasites within erythrocytes:
a. Primaquine
b. Pyrimethamine
C. Quinacrine
d. Chloroquine

a. Primaquine

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An ion that often shows expectorant action is:
a. lodide
b. phosphate
c. flouride
C. lodate

a. lodide

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Aluminon reagent is chemically:
a. Tri-ammonium surintricarboxylic acid
b. Tri-ammonium aurin-tricarboxylate
c. Aluminum salts of carboxylate acid
d. None of these

b. Tri-ammonium aurin-tricarboxylate

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The only single acid that can
dissolve gold
a. Hydrochloric acid
b. Nitric acid
c. Selenic acid
d. Aqua regia

c. Selenic acid

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Precipitated sulfur is also known as:
a. Sublimed sulfur
b. Lac sulfur
c. Milk sulfur
d. B and C

d. B and C

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Equal amounts of isomers are called a_____
a. Levorotatory
b. Dextrorotatory
c. Racemic mixture
d. Optically active

c. Racemic mixture

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Borates in turmeric paper is colored
a. Olive
b. Green
c. White
d. Orange to red

d. Orange to red

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When a reaction is at equilibrium, its Gibbs Free Energy Is
a. Positive
b. Zero
c. Negative
d. Non-spontaneous

b. Zero

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A law that states that the entropy of
a pure, crystalline solid at absolute zero temperature is zero
a. Thirds law of thermodynamics
b. Second law of thermodynamics
C. Zeroth law of thermodynamics
d. First law of thermodynamics

a. Thirds law of thermodynamics

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Babbit metal is a combination of a
a. 80% Sn, 20% Sb
b. 80% Cu, 20% Sb
c. 80% Sb, 20% Sn
d. 20% Cu, 80% Sn

a. 80% Sn, 20% Sb

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In weakly acidic solution, stannous
chloride with metallic gold slowly turns down precipitate called:
а. Purple of Caysus
b. Purple of Cassius
c. Cassius red
d. a and b

b. Purple of Cassius

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To prepare White Lotion, USP
sulfurated potash is added to:
а. Zinc sulfide
b. Zinc oxide
c. Zinc sulfate
d. None of these

c. Zinc sulfate

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It is added in glass to hide the blue
green color of iron
a. Manganese dioxide
b. Lead
c. Potassium
d. Borates

a. Manganese dioxide

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It decolorizes potassium
permanganate and iodine solution
a. Peroxides
b. Thiocyanates
c. Thiosulfates
d. Dichromates

c. Thiosulfates

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Sequestering agent for Benedict
solution
a. Citrate
b. Tartrate
c. Glycerin
d. Sulfate

a. Citrate

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Litharge is a. Lead carbonate b. Lead acetate c. Lead monoxide d. Lead subacetate

c. Lead monoxide

Soft coal is a. Anthracite b. Bituminous c. Charcoal d. Activated charcoal

b. Bituminous

Frasch process is used to obtain the element a. Tellurium b. Sulfur c. Selenium d. Silicon

b. Sulfur

Antidote in the treatment of cyanide poisoning and has a vasodilating effect a. Sodium nitrite b. Sodium nitrate C. Amyl nitrate nitric d. Potassium lodide

a. Sodium nitrite

The temperature change experienced by an object when it absorbs a certain amount of energy is determined by a. Specific heat b. Heat of fusion c. Heat capacity d. Molar heat capacity

c. Heat capacity

Chalcogens are a. Group V b. Group Ill c. Group IV d. Group VI

d. Group VI

Dimethylglyoxime reagent is specific for a. Magnesium b. Nickel c. Cobalt d. Copper

b. Nickel

Combined with Strong Ammonia Solution, it has been used as smelling salts a. Aromatic Ammonia Spirit b. Spirit of Mindererus c. Preston Salt d. All of the above

c. Preston Salt

Which would qualify to produce a silver mirror on the walls of a test tube with silver nitrate? a. Acetone b. Formaldehyde c. Glucose d. b and c

d. b and c

An organic compound with a molecular formula C10H22 is most likely an a. Alkane b. Alkene c. Alkyne d. Cycloalkene

a. Alkane

These are equal mixtures of two mirror image Isomers a. Meso compounds b. Racemic compounds c. Anomeric compounds d. Epimeric compounds e. Enantiomeric compounds

b. Racemic compounds

Which form of insulin is absorbed and interacts with the insulin receptors? a. Monomer b. Dimer c. Tetramer d. Pentamer e. Hexamer

a. Monomer

Potassium supplements are administered in all the following manners except: a. Infusion b. Elixir PO c. Slow release PO d. Rapid IV injection e. Effervescent salts

d. Rapid IV injection

38. Native hydrated aluminum silicates is also known as a a. Kaolin b. Pumice c. Bentonite d. Talc e. Siloxane

a. Kaolin

Target enzyme of sulfonamides a. Dihydrofolate reductase b. Dihydroorotate dehydrogenase c. Dihydropteroate synthase d. Sulfotransferase

c. Dihydropteroate synthase

Preservatives like parabens increase their preservative property by: a. Reducing the parent compound b. Decreasing molecular weight c. Attaching a halogen to the parent compound d. Substituting the parent compound with a lipophilic group e. Increasing the molecular weight

e. Increasing the molecular weight

Render the glass brown a. Rare earths b. Borate c. Lead d. Potassium e. MnO2

e. MnO2

Methoxybenzene is also known as a. Toulene b. Aniline c. Anisole d. Xylene e. None of the above

d. Xylene

Which of the following contain KI: I. lodine solution II. Lugols solution III. Strong iodine tincture IV. Iodine tincture a. I and I b. Ill and IV c. II and Ill d. I and IV e. All of the above

c. II and Ill

Chloramphenicol a. Streptococcus orientalis b. Penicillium griseofulvum c. Streptomyces griseus d. Streptomyces venezuelae

d. Streptomyces venezuelae

What is the official barium salt used in medicine as a radiopaque substance in roentgenographic examination of the GIT? a. BaCl2 b. Ba (NO3)2 c. BaSO4 d. Ba (OH)2

c. BaSO4

Among the given halogens, which element is the most metallic? a. Chlorine b. Fluorine c. Astatine d. Bromine e. lodine

c. Astatine

Calomel a. HgCl2 b. Hg2Cl2 c. Ammoniated mercury d. Ammoniated silver nitrate e. Lead acetate

b. Hg2Cl2

48. When a carbonyl group reacts with a primary amine, what will be the resulting product? a. Imine b. Tertiary amine c. Secondary amine d. Amide e. Enamine

a. Imine

The addition of a hydrogen molecule to an alkene is catalyzed by what metal? a. Silver b. Beryllium c. Osmium d. Palladium e. Gallium

d. Palladium

This compound is derived from the pyrolysis of castor oil and is used as an antifungal a. Azelaic acid b. Chrysobactin c. Propionic acid d. Salicylic acid e. Undecylenic acid

e. Undecylenic acid

Energy released when an electron is added to a neutral atom or molecule in their gaseous state a. Electronegativity b. lonization energy c. Electron affinity d. First ionization energy

c. Electron affinity

The following are properties of colloids except: a. Exhibit brownian motion  b. Exhibit Tyndall effect c. Electrically neutral d. Include gels, sols, and emulsions

c. Electrically neutral

Method for production of Magnesium a. Hall-Heroult Process b. Messerschmidt Process C. Linde-Frankl Process d. Dow Process

d. Dow Process

A reaction with a positive enthalpy is said to be a. Reversible b. Spontaneous c. Endothermic d. Exothermic

c. Endothermic

Diphenoxylate is a structural analog of a. Dilantin b. Codeine c. Meperidine d. Naloxone

c. Meperidine

This describes the relative position of an energy present level with respect to the other energy levels a. Principal quantum number b. Azimuthal quantum number sh c. Magnetic quantum number * d. Spin quantum number

a. Principal quantum number

This is a chronic condition resembling tuberculosis in symptom: a. Silicosis b. G-Lilles c. Parakeratosis d. Itai-Itai disease e. Minamata disease

a. Silicosis

The compound with the formula, CH3CH2COCH2CH3 is an: a. Ketone b. Aldehyde c. Carboxylic acid d. Ether e. Ester

a. Ketone

What is the IUPAC name of valproic acid a. 2-methylpropanoic acid b. 2-ethylbutanoic acid. c. 2-propylpentanoic acid d. 2-butylhexanoic acid e. 2-penty/heptanoic acid

c. 2-propylpentanoic acid

The sum of the number of protons and neutrons: a. Atomic number b. Atomic mass c. Mass number d. isotope

c. Mass number

Acids have the following properties except: a. pH below 7 b. Acceptor of protons c. Neutralize bases d. Sour taste

b. Acceptor of protons

The ion that gives positive result to Rinmanns green a. Aluminum b. Chromium c. Manganese d. Zinc

d. Zinc

Standard temperature for gas a. 0°C b. 298 K c. 273 K d. a and c

d. a and c

Trans-2-alkene I. Asymmetrical II. Non-polar III. High melting point IV. Lower boiling point a. I, II, III b. II, III, IV c. I, III, IV d. I, II, III, IV

b. II, III, IV

All of the following are sources of calcium except: I. Talc II. Gypsum III. Dolomite IV. Cryolite a. I and Ill b. II and III c. I and IV d. All of the above

c. I and IV

Which of the following is true? a. Boron belongs to group 3A b. Nitrogen belongs to group 4A X c. Chalcogens are elements belonging to group 7A, which are the most electronegative elements d. None of the above

a. Boron belongs to group 3A

Kayser-Fleischer ring a. Cu toxicity b. Co toxicity c. AP toxicity d. Cd toxicity

a. Cu toxicity

Plaster of Paris a. Sodium sulfate b. Magnesium sulfate c. Calcium sulfate hemihydrate d. Calcium sulfate dihydrate e. Cupric sulfate

c. Calcium sulfate hemihydrate

Calculate the molality of a sulfuric acid solution containing 24.4 g of sulfuric acid in 198 g of water. The molar mass of sulfuric acid is 98.09g. a. 1.16m b. 1.26 m c. 1.36 m d. 1,46 m

b. 1.26 m

Which of the following statements is NOT true about half-life of radioisotopes? a. The faster the isotope decays the more stable it is b. Half-life is the time it takes for radioactivity to reduce by 50% c. The faster the isotope decays the more unstable it is  d. The half-life is unique for any given isotope

a. The faster the isotope decays the more stable it is

It states that the total pressure of a mixture of gasses is equal to the sum of the partial pressure of its component gasses a. Grahams law b. Daltons law of partial pressure c. Combined gas law d. Law of volumes

b. Daltons law of partial pressure

For a weak acid, when the pH of the solution is the same as that of the pKa of the acid, the percentage of ionization of the acid will be: a. 25% b. 50% c. 75% d. 100%

b. 50%

76. Potassium aluminum silicates a. Cryolites b. Zeolite c. Feldspars d. Chlorites

c. Feldspars

A certain bond of a compound has an electronegativity difference of 0.8, therefore the bond is: a. Tonic b. Polar covalent c. Non-polar covalent d. NOTA

b. Polar covalent

Which of the following are deliquescent substances? I. NaOH II. CaO III. NaNO: IV. NaCI a. I, II b. II, III c. I, III d. II, IV

c. I, III

All of the following ions are present in the ntracellular Tuids except a. K+ b. Na+ C. Mg 2+ d. HPO42+

b. Na+

Also known as flowers of sulfur a. Amorphous sulfur b. Precipitated sulfur C. Sublime sulfur d. Plastic sulfur e. None of the above

C. Sublime sulfur

The negative log of the hydroxide ion concentration of CHaCOOH will solve for a. [H*] b. рОН c. OH d. Ph

b. рОН

Used as an anticonvulsant in the treatment of pre-eclampsia a. Sodium potassium tartrate b. Magnesium sulfate C. Potassium bitartrate d. Sodium sulfate

b. Magnesium sulfate

83. It is an 8 carbon dicarboxylic acid. a. Adipic acid b. Azelaic acid C. Succinic acid D. Suberic acid e. Sebacic acid

D. Suberic acid

A substance that cannot be separated into simpler substances by chemical means a. Compound b. Element C. Mixture d. Solution

b. Element

Which of the following is an example of a nonpolar compound a. Chloroform b. Carbon tetrachloride c. Hydrochloric acid d. Ethanol

b. Carbon tetrachloride

True about resonance I. Involves delocalization of both sigma and pi bonds II. Overall charge of the system remains the same IlI. Bonding can be expressed by one single Lewis’s formula a. I, III b. II c. IIII d. I, II, III

b. II

Which of the tests will NOT give a positive result with acetone? I. Brady test Il. lodoform test III. Fehlings test IV. Jones oxidation V. Hinsberg test a. I, II, IV, V b. l and Il C. III, IV, V d. I, II, III, IV, V

C. III, IV, V

What is the method used in the production of dry ice? a. Sublimation b. Condensation c. Deposition d Evaporation

c. Deposition

The hydrogen will be received by the less stable carbon upon addition reactions based on the a. Markovnikov rule b. Huckels rule c. Hunds rule d. Zairtsev’s rule

a. Markovnikov rule

Susceptibility to hydrolysis from most susceptible to least susceptible a. Amides >Esters> Anhydrides > Acylhalide b. Acyl halide >Anhydrides >Esters >Amides c. Esters>Acyl halides >Anhydrides >Amides d. Anhydrides > Esters > Amides >Acyl halides

b. Acyl halide >Anhydrides >Esters >Amides

Which has the formula = moles solute / kg solution a. Osmolality b. Molarity c. Molality Normality d. NOTA

d. NOTA

Five bonding electron pairs and one lone pair a Square pyramidal b. Trigonal pyramidal c. Trigonal planar d. Trigonal bipyramidal

a Square pyramidal

Which anion evolves a gas with a fruity odor when treated with concentrated sulfuric acid and ethanol? a. CIO b. SO с. CH3COO d. BrO

с. CH3COO

Which of the following are true about catalysts? a. They are consumed b. They decrease activation energy c. They affect equilibrium d. All of the above e. None of the above

b. They decrease activation energy

Which of the following is NOT true? a. The Cann-Ingold-Prelog rules are used for naming enantiomers and diastereomers b. The D- and L- configuration is also called the (+) and (-) notation / c. Two groups with higher priorities on the same side is described as (2)- Isomer d. None of the above

b. The D- and L- configuration is also called the (+) and (-) notation /

Given the electron richness of benzene, which of the following mechanisms make the most sense for benzenes reactivity? a. Nucleophilic substitution, b. Free radical substitution c. Electrophilic substitution d. Nucleophilic addition

c. Electrophilic substitution

Form of water most commonly used as a solvent during manufacture of parenteral? a. Sterile water for injection b. Bacteriostatic water c. Water for injection d. Purified water

c. Water for injection

In qualitative analysis, which group of cations does Nat belong to? a. Group I b. Group C. Group Ill d. Group IV e. Group V

e. Group V

Condys crystals a. Oxidizing agent b. Reducing agent c. Preservative d. Acidifying agent

a. Oxidizing agent

What class of organic compounds will result a subjecting primary alcohol to Dess-Martin periodinane? a. Aldehyde b. DHP - partial oxidation c. Alkyl halide d. Carboxylic acid e. Ketone

a. Aldehyde

MOD 1 Flashcards

(97 cards)