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RPh 2024! > MOD 1 > Flashcards

MOD 1 Flashcards

1
Q

The structure given below represents the common structure of which group of drugs?
a. Benzodiazepines
b. Barbiturates
c. Phenothiazines
d. SSRIs
e. MAO-inhibitors

A

b. Barbiturates

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2
Q

Which of the following is/are true
regarding methylation?
I. Generally leads to less polar or water-soluble metabolites
II. Important in the biosynthesis of many endogenous compounds like
epinephrine and melatonin
III. Constitutes only a minor pathway for conjugating drugs or xenobiotic
a. I only
b. I, II, III
C. I, II
d. I, III
e. II, III

A

e. II, III

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3
Q

The process involved in the
biotransformation of amitriptyline to nortriptyline.
a. Ketone reduction
b. Ester hydrolysis
c. Epoxidation
d. Aromatic hydroxylation
e. N- demethylation

A

e. N- demethylation

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4
Q

Generally accepted other names of
Alcohol, USP
I. Ethanol
II. Wood alcohol / Methanol
III. Spiritus vini rectificatus
IV. Wine spirit
a. I, IV
b. I, II, III
c. I, III, IV
d. I, III
e. I only

A

c. I, III, IV

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5
Q

The antibiotic that binds with
ribosome 30s subunit
a. Chloramphenicol
b. Tetracycline
C. Erythromycin
d. Lincomycins
e. Penicillins

A

b. Tetracycline

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6
Q

Macrolide antibiotics have these
common characteristics:
I. Large lactone ring
II. Ketone group
Ill. A glycosidic ally linked amino sugar
IV. A symmetric carbon atoms in the
acylamido propanediol chain
a. I only
b. II only
c. I, II, III
d. II, III

A

c. I, II, III

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7
Q

Analogue of podophyllotoxin that is
an inhibitor of topoisomerase Il which contains methyl as its R group
a. Vindoline
b. Etoposide
c. Vincristine
d. Epipodophyllotoxin
e. Daunorubicin

A

b. Etoposide

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8
Q

Drowsiness is a side effect of
antihistamines that is most common to the
a. Ethylenediamines
b. Tertiary aminoalkyl ethers
C. Phenothiazines
d. H2-receptor antagonists
e. Cimetidine

A

b. Tertiary aminoalkyl ethers

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9
Q

Diagonally related pairs of elements
in the periodic table is known as:
a. Metalloids
b. Bridge elements
C. Representative elements
d. Lanthanide series

A

b. Bridge elements

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10
Q

The drug most effective against
malarial parasites in the liver but not effective against parasites within erythrocytes:
a. Primaquine
b. Pyrimethamine
C. Quinacrine
d. Chloroquine

A

a. Primaquine

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11
Q

An ion that often shows expectorant action is:
a. lodide
b. phosphate
c. flouride
C. lodate

A

a. lodide

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12
Q

Aluminon reagent is chemically:
a. Tri-ammonium surintricarboxylic acid
b. Tri-ammonium aurin-tricarboxylate
c. Aluminum salts of carboxylate acid
d. None of these

A

b. Tri-ammonium aurin-tricarboxylate

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13
Q

The only single acid that can
dissolve gold
a. Hydrochloric acid
b. Nitric acid
c. Selenic acid
d. Aqua regia

A

c. Selenic acid

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14
Q

Precipitated sulfur is also known as:
a. Sublimed sulfur
b. Lac sulfur
c. Milk sulfur
d. B and C

A

d. B and C

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15
Q

Equal amounts of isomers are called a_____
a. Levorotatory
b. Dextrorotatory
c. Racemic mixture
d. Optically active

A

c. Racemic mixture

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16
Q

Borates in turmeric paper is colored
a. Olive
b. Green
c. White
d. Orange to red

A

d. Orange to red

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17
Q

When a reaction is at equilibrium, its Gibbs Free Energy Is
a. Positive
b. Zero
c. Negative
d. Non-spontaneous

A

b. Zero

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18
Q

A law that states that the entropy of
a pure, crystalline solid at absolute zero temperature is zero
a. Thirds law of thermodynamics
b. Second law of thermodynamics
C. Zeroth law of thermodynamics
d. First law of thermodynamics

A

a. Thirds law of thermodynamics

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19
Q

Babbit metal is a combination of a
a. 80% Sn, 20% Sb
b. 80% Cu, 20% Sb
c. 80% Sb, 20% Sn
d. 20% Cu, 80% Sn

A

a. 80% Sn, 20% Sb

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20
Q

In weakly acidic solution, stannous
chloride with metallic gold slowly turns down precipitate called:
а. Purple of Caysus
b. Purple of Cassius
c. Cassius red
d. a and b

A

b. Purple of Cassius

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21
Q

To prepare White Lotion, USP
sulfurated potash is added to:
а. Zinc sulfide
b. Zinc oxide
c. Zinc sulfate
d. None of these

A

c. Zinc sulfate

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22
Q

It is added in glass to hide the blue
green color of iron
a. Manganese dioxide
b. Lead
c. Potassium
d. Borates

A

a. Manganese dioxide

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23
Q

It decolorizes potassium
permanganate and iodine solution
a. Peroxides
b. Thiocyanates
c. Thiosulfates
d. Dichromates

A

c. Thiosulfates

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24
Q

Sequestering agent for Benedict
solution
a. Citrate
b. Tartrate
c. Glycerin
d. Sulfate

A

a. Citrate

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25
Q

Litharge is
a. Lead carbonate
b. Lead acetate
c. Lead monoxide
d. Lead subacetate

A

c. Lead monoxide

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26
Q

Soft coal is
a. Anthracite
b. Bituminous
c. Charcoal
d. Activated charcoal

A

b. Bituminous

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27
Q

Frasch process is used to obtain the
element
a. Tellurium
b. Sulfur
c. Selenium
d. Silicon

A

b. Sulfur

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28
Q

Antidote in the treatment of cyanide poisoning and has a vasodilating effect
a. Sodium nitrite
b. Sodium nitrate
C. Amyl nitrate nitric
d. Potassium lodide

A

a. Sodium nitrite

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29
Q

The temperature change
experienced by an object when it
absorbs a certain amount of energy is determined by
a. Specific heat
b. Heat of fusion
c. Heat capacity
d. Molar heat capacity

A

c. Heat capacity

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30
Q

Chalcogens are
a. Group V
b. Group Ill
c. Group IV
d. Group VI

A

d. Group VI

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31
Q

Dimethylglyoxime reagent is specific for
a. Magnesium
b. Nickel
c. Cobalt
d. Copper

A

b. Nickel

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32
Q

Combined with Strong Ammonia
Solution, it has been used as smelling salts
a. Aromatic Ammonia Spirit
b. Spirit of Mindererus
c. Preston Salt
d. All of the above

A

c. Preston Salt

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33
Q

Which would qualify to produce a
silver mirror on the walls of a test tube with silver nitrate?
a. Acetone
b. Formaldehyde
c. Glucose
d. b and c

A

d. b and c

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34
Q

An organic compound with a
molecular formula C10H22 is most likely an
a. Alkane
b. Alkene
c. Alkyne
d. Cycloalkene

A

a. Alkane

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35
Q

These are equal mixtures of two
mirror image Isomers
a. Meso compounds
b. Racemic compounds
c. Anomeric compounds
d. Epimeric compounds
e. Enantiomeric compounds

A

b. Racemic compounds

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36
Q

Which form of insulin is absorbed
and interacts with the insulin receptors?
a. Monomer
b. Dimer
c. Tetramer
d. Pentamer
e. Hexamer

A

a. Monomer

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37
Q

Potassium supplements are
administered in all the following
manners except:
a. Infusion
b. Elixir PO
c. Slow release PO
d. Rapid IV injection
e. Effervescent salts

A

d. Rapid IV injection

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38
Q
  1. Native hydrated aluminum silicates is also known as a
    a. Kaolin
    b. Pumice
    c. Bentonite
    d. Talc
    e. Siloxane
A

a. Kaolin

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39
Q

Target enzyme of sulfonamides
a. Dihydrofolate reductase
b. Dihydroorotate dehydrogenase
c. Dihydropteroate synthase
d. Sulfotransferase

A

c. Dihydropteroate synthase

40
Q

Preservatives like parabens
increase their preservative property by:
a. Reducing the parent compound
b. Decreasing molecular weight
c. Attaching a halogen to the parent
compound
d. Substituting the parent compound with a lipophilic group
e. Increasing the molecular weight

A

e. Increasing the molecular weight

41
Q

Render the glass brown
a. Rare earths
b. Borate
c. Lead
d. Potassium
e. MnO2

A

e. MnO2

42
Q

Methoxybenzene is also known as
a. Toulene
b. Aniline
c. Anisole
d. Xylene
e. None of the above

A

d. Xylene

43
Q

Which of the following contain KI:
I. lodine solution
II. Lugols solution
III. Strong iodine tincture
IV. Iodine tincture
a. I and I
b. Ill and IV
c. II and Ill
d. I and IV
e. All of the above

A

c. II and Ill

44
Q

Chloramphenicol
a. Streptococcus orientalis
b. Penicillium griseofulvum
c. Streptomyces griseus
d. Streptomyces venezuelae

A

d. Streptomyces venezuelae

45
Q

What is the official barium salt used
in medicine as a radiopaque substance
in roentgenographic examination of the GIT?
a. BaCl2
b. Ba (NO3)2
c. BaSO4
d. Ba (OH)2

A

c. BaSO4

46
Q

Among the given halogens, which
element is the most metallic?
a. Chlorine
b. Fluorine
c. Astatine
d. Bromine
e. lodine

A

c. Astatine

47
Q

Calomel
a. HgCl2
b. Hg2Cl2
c. Ammoniated mercury
d. Ammoniated silver nitrate
e. Lead acetate

A

b. Hg2Cl2

48
Q
  1. When a carbonyl group reacts with a primary amine, what will be the resulting product?
    a. Imine
    b. Tertiary amine
    c. Secondary amine
    d. Amide
    e. Enamine
A

a. Imine

49
Q

The addition of a hydrogen molecule to an alkene is catalyzed by what metal?
a. Silver
b. Beryllium
c. Osmium
d. Palladium
e. Gallium

A

d. Palladium

50
Q

This compound is derived from the
pyrolysis of castor oil and is used as an antifungal
a. Azelaic acid
b. Chrysobactin
c. Propionic acid
d. Salicylic acid
e. Undecylenic acid

A

e. Undecylenic acid

51
Q

Energy released when an electron is
added to a neutral atom or molecule in their gaseous state
a. Electronegativity
b. lonization energy
c. Electron affinity
d. First ionization energy

A

c. Electron affinity

52
Q

The following are properties of
colloids except:
a. Exhibit brownian motion

b. Exhibit Tyndall effect
c. Electrically neutral
d. Include gels, sols, and emulsions

A

c. Electrically neutral

53
Q

Method for production of Magnesium
a. Hall-Heroult Process
b. Messerschmidt Process
C. Linde-Frankl Process
d. Dow Process

A

d. Dow Process

54
Q

A reaction with a positive enthalpy is said to be
a. Reversible
b. Spontaneous
c. Endothermic
d. Exothermic

A

c. Endothermic

55
Q

Diphenoxylate is a structural analog
of
a. Dilantin
b. Codeine
c. Meperidine
d. Naloxone

A

c. Meperidine

56
Q

This describes the relative position
of an energy present level with respect to the other energy levels
a. Principal quantum number
b. Azimuthal quantum number sh
c. Magnetic quantum number *
d. Spin quantum number

A

a. Principal quantum number

57
Q

This is a chronic condition
resembling tuberculosis in symptom:
a. Silicosis
b. G-Lilles
c. Parakeratosis
d. Itai-Itai disease
e. Minamata disease

A

a. Silicosis

58
Q

The compound with the formula,
CH3CH2COCH2CH3 is an:
a. Ketone
b. Aldehyde
c. Carboxylic acid
d. Ether
e. Ester

A

a. Ketone

59
Q

What is the IUPAC name of valproic
acid
a. 2-methylpropanoic acid
b. 2-ethylbutanoic acid.
c. 2-propylpentanoic acid
d. 2-butylhexanoic acid
e. 2-penty/heptanoic acid

A

c. 2-propylpentanoic acid

60
Q

The sum of the number of protons
and neutrons:
a. Atomic number
b. Atomic mass
c. Mass number
d. isotope

A

c. Mass number

61
Q

Acids have the following properties
except:
a. pH below 7
b. Acceptor of protons
c. Neutralize bases
d. Sour taste

A

b. Acceptor of protons

62
Q

The ion that gives positive result to
Rinmanns green
a. Aluminum
b. Chromium
c. Manganese
d. Zinc

A

d. Zinc

63
Q

Standard temperature for gas
a. 0°C
b. 298 K
c. 273 K
d. a and c

A

d. a and c

64
Q

Trans-2-alkene
I. Asymmetrical
II. Non-polar
III. High melting point
IV. Lower boiling point
a. I, II, III
b. II, III, IV
c. I, III, IV
d. I, II, III, IV

A

b. II, III, IV

65
Q

All of the following are sources of
calcium except:
I. Talc
II. Gypsum
III. Dolomite
IV. Cryolite
a. I and Ill
b. II and III
c. I and IV
d. All of the above

A

c. I and IV

66
Q

Which of the following is true?
a. Boron belongs to group 3A
b. Nitrogen belongs to group 4A X
c. Chalcogens are elements belonging to group 7A, which are the most electronegative elements
d. None of the above

A

a. Boron belongs to group 3A

67
Q

Kayser-Fleischer ring
a. Cu toxicity
b. Co toxicity
c. AP toxicity
d. Cd toxicity

A

a. Cu toxicity

68
Q

Plaster of Paris
a. Sodium sulfate
b. Magnesium sulfate
c. Calcium sulfate hemihydrate
d. Calcium sulfate dihydrate
e. Cupric sulfate

A

c. Calcium sulfate hemihydrate

69
Q

Calculate the molality of a sulfuric
acid solution containing 24.4 g of
sulfuric acid in 198 g of water. The
molar mass of sulfuric acid is 98.09g.
a. 1.16m
b. 1.26 m
c. 1.36 m
d. 1,46 m

A

b. 1.26 m

70
Q

Which of the following statements is NOT true about half-life of
radioisotopes?
a. The faster the isotope decays the
more stable it is
b. Half-life is the time it takes for
radioactivity to reduce by 50%
c. The faster the isotope decays the
more unstable it is

d. The half-life is
unique for any given isotope

A

a. The faster the isotope decays the
more stable it is

71
Q

It states that the total pressure of a
mixture of gasses is equal to the sum of the partial pressure of its component gasses
a. Grahams law
b. Daltons law of partial pressure
c. Combined gas law
d. Law of volumes

A

b. Daltons law of partial pressure

72
Q

For a weak acid, when the pH of the
solution is the same as that of the pKa of the acid, the percentage of ionization of the acid will be:
a. 25%
b. 50%
c. 75%
d. 100%

A

b. 50%

73
Q
  1. Potassium aluminum silicates
    a. Cryolites
    b. Zeolite
    c. Feldspars
    d. Chlorites
A

c. Feldspars

74
Q

A certain bond of a compound has
an electronegativity difference of 0.8, therefore the bond is:
a. Tonic
b. Polar covalent
c. Non-polar covalent
d. NOTA

A

b. Polar covalent

75
Q

Which of the following are
deliquescent substances?
I. NaOH
II. CaO
III. NaNO:
IV. NaCI
a. I, II
b. II, III
c. I, III
d. II, IV

A

c. I, III

76
Q

All of the following ions are present
in the ntracellular Tuids except
a. K+
b. Na+
C. Mg 2+
d. HPO42+

A

b. Na+

77
Q

Also known as flowers of sulfur
a. Amorphous sulfur
b. Precipitated sulfur
C. Sublime sulfur
d. Plastic sulfur
e. None of the above

A

C. Sublime sulfur

78
Q

The negative log of the hydroxide
ion concentration of CHaCOOH will
solve for
a. [H*]
b. рОН
c. OH
d. Ph

A

b. рОН

79
Q

Used as an anticonvulsant in the
treatment of pre-eclampsia
a. Sodium potassium tartrate
b. Magnesium sulfate
C. Potassium bitartrate
d. Sodium sulfate

A

b. Magnesium sulfate

80
Q
  1. It is an 8 carbon dicarboxylic acid.
    a. Adipic acid
    b. Azelaic acid
    C. Succinic acid
    D. Suberic acid
    e. Sebacic acid
A

D. Suberic acid

81
Q

A substance that cannot be
separated into simpler substances by chemical means
a. Compound
b. Element
C. Mixture
d. Solution

A

b. Element

82
Q

Which of the following is an example of a nonpolar compound
a. Chloroform
b. Carbon tetrachloride
c. Hydrochloric acid
d. Ethanol

A

b. Carbon tetrachloride

83
Q

True about resonance
I. Involves delocalization of both sigma and pi bonds
II. Overall charge of the system remains the same
IlI. Bonding can be expressed by one single Lewis’s formula
a. I, III
b. II
c. IIII
d. I, II, III

A

b. II

84
Q

Which of the tests will NOT give a
positive result with acetone?
I. Brady test
Il. lodoform test
III. Fehlings test
IV. Jones oxidation
V. Hinsberg test
a. I, II, IV, V
b. l and Il
C. III, IV, V
d. I, II, III, IV, V

A

C. III, IV, V

85
Q

What is the method used in the
production of dry ice?
a. Sublimation
b. Condensation
c. Deposition
d Evaporation

A

c. Deposition

86
Q

The hydrogen will be received by the less stable carbon upon addition reactions based on the
a. Markovnikov rule
b. Huckels rule
c. Hunds rule
d. Zairtsev’s rule

A

a. Markovnikov rule

87
Q

Susceptibility to hydrolysis from
most susceptible to least susceptible
a. Amides >Esters> Anhydrides >
Acylhalide
b. Acyl halide >Anhydrides >Esters
>Amides
c. Esters>Acyl halides >Anhydrides
>Amides
d. Anhydrides > Esters > Amides >Acyl halides

A

b. Acyl halide >Anhydrides >Esters
>Amides

88
Q

Which has the formula = moles
solute / kg solution
a. Osmolality
b. Molarity
c. Molality Normality
d. NOTA

A

d. NOTA

89
Q

Five bonding electron pairs and one
lone pair
a Square pyramidal
b. Trigonal pyramidal
c. Trigonal planar
d. Trigonal bipyramidal

A

a Square pyramidal

90
Q

Which anion evolves a gas with a
fruity odor when treated with
concentrated sulfuric acid and ethanol?
a. CIO
b. SO
с. CH3COO
d. BrO

A

с. CH3COO

91
Q

Which of the following are true about catalysts?
a. They are consumed
b. They decrease activation energy
c. They affect equilibrium
d. All of the above
e. None of the above

A

b. They decrease activation energy

92
Q

Which of the following is NOT true?
a. The Cann-Ingold-Prelog rules are
used for naming enantiomers and
diastereomers
b. The D- and L- configuration is also called the (+) and (-) notation /
c. Two groups with higher priorities on the same side is described as (2)-
Isomer
d. None of the above

A

b. The D- and L- configuration is also called the (+) and (-) notation /

93
Q

Given the electron richness of
benzene, which of the following
mechanisms make the most sense for benzenes reactivity?
a. Nucleophilic substitution,
b. Free radical substitution
c. Electrophilic substitution
d. Nucleophilic addition

A

c. Electrophilic substitution

94
Q

Form of water most commonly used as a solvent during manufacture of parenteral?
a. Sterile water for injection
b. Bacteriostatic water
c. Water for injection
d. Purified water

A

c. Water for injection

95
Q

In qualitative analysis, which group
of cations does Nat belong to?
a. Group I
b. Group
C. Group Ill
d. Group IV
e. Group V

A

e. Group V

96
Q

Condys crystals
a. Oxidizing agent
b. Reducing agent
c. Preservative
d. Acidifying agent

A

a. Oxidizing agent

97
Q

What class of organic compounds
will result a subjecting primary alcohol to Dess-Martin periodinane?
a. Aldehyde
b. DHP - partial oxidation
c. Alkyl halide
d. Carboxylic acid
e. Ketone

A

a. Aldehyde

RPh 2024! (5 decks)

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