mock revision 9-14 Flashcards
circularitory system consists of:
a pump (heart), blood vessels (to carry around blood), valves (to make sure blood flow is only one way)
the heart:
Atrium (top), ventricle (bottom) and left and right
Left walls are thicker since pumps all around body, right pumps to lungs.
process of blood flow in heart
Blood flows into the atria from veins
The atria contracts, pushing blood into ventricles, the fall in pressure in atria causes the atrioventricular (ventricle to atria) valve to close
Ventricle contracts, pushing blood into the arteries. The fall in pressure causes semilunar (atria to ventricle) vale to close
Arteries:
Carry blood away from heart, oxygenated
Thick outer wall, small lumen, smooth lining, thick muscle layer
Don’t have valves due to the pressure ensures the movement
The arteries divide a turn into capillaries, then into veins
Capillaries
Wall made from layer of single cells, very small lumen
Veins
Thin outer wall, large lumen, smooth lining, thin muscle layer
Have valves to ensure blood flow
Blood contains:
Plasma- has blood cells, ions, hormones and co2
Platies- form blood clots, have cell fragments
Red blood cells- contain haemoglobin (no nucleus, can fit into capillaries, large sa for o2 to diffuse, biconcave disk) which have o2
White blood cells- produce antibodies/ contain DNA or other gene
Phagocytes: weird shape, ingest bad particles
Lymphocytes- round nucleus produce antibodies
Blood clotting
fibrinogen (found in blood plasma)- fibrin (forms scab) + red blood cells+ white blood cells and platelets (temporary plug form blood clots+ converts fibrinogen to fibrin.
Pathogen
disease causing organism (bacteria, fungi, Protoctista). In host reproduces rapidly, them or their waste products damage cells and organs.
Antigen
found on pathogens, a toxin or other foreign substance which induces an immune response in the body, especially the production of antibodies. Have binding sites to antibodies
First line of defence against pathogens
nose hairs, mucus, skin, stomach acid
2nd line of defence
white blood cells (phagocytes) engulf pathogens, antigens trigger to produce antibodies which mark cells for destruction (produced by lymphocytes, a type of white blood cell). Memory t cells remain in blood and remember what antibodies was needed for specific issues (immunity)
getting a vaccine, then getting the pathogen again:
Injection of vaccine
Primary response- lymphocytes produce antibodies
Injected antigen is destroyed by antibodies
Memory cells are produced
If they get the pathogen again:
Secondary response, memory cells recognise and produce antibodies quickly
Pathogen is destroyed
Types of immunity:
Naturally
Active: pathogen enters body, body induces antibodies and memory cells
Passive(memory cells not produced) : passed from mum to baby via milk or placenta
Artificial
Active: vaccines, body produces antibodies
Passive (memory cells not poduced): preformed antibodies in immune system, introduces via injection, for sick people
Chorea (bacteria) causes
watery diarrhoea, dehydration, caused from vibrio cholerae in contaminated h20.
if you get chlorea
It can pass through stomach and bacteria produces the chorea toxin in small intestines
Causes intestinal cells to produce chloride ions to lumen
Causes osmatic movement of water to lumen (internal space)
Body can’t absorb anything, loss of ions and dehydration.
Air goes
nose/mouth- larynx- trachea- bronchi- bronchioles- alveoli