MOAs quick recognition

Question 1

Vasodilates

Answer 1

Prostacyclin

Question 2

Opioid agonist

Answer 2

Eluxadoline

antispasmodic IBS-D

Question 3

Golimumab

Answer 3

TNF alpha blocker

Question 4

Inhibits platelet aggregation, vasodilates

Answer 4

PGI2

Question 5

Inhibits pyrimidine synthesis by inhibiting dihydrooratate dehydrogenase

Answer 5

Leflunomide

Question 6

Prostaglandin E1 analogues

Answer 6

Misoprostol (anti-inflammatory)

Lubiprostone (Cl- channels increase fluids for constipation)

Question 7

Partial agonist activity on alpha receptors leads to increased vasoconstriction

Answer 7

Ergotamine

Question 8

Binds to CD20, blocking B cells (good for lymphomas)

Answer 8

Rituximab

Question 9

Blocks D2 receptor to decrease motility

Answer 9

Metoclopramide

Question 10

Blocks IL-1

Answer 10

Anakira

Question 11

Increase B adrenergic tone leads to better response to SABAs/LABAs

Answer 11

Inhaled corticosteroids

Question 12

Gs coupled

increase cAMP

Answer 12

H2 receptor

Question 13

Inhibits assembly of microtubules by binding to tubulin

Answer 13

Colchicine

Question 14

Increase cAMP to relax smooth muscle

Answer 14

B2 agonists

Theophylline (by inhibiting phosphodiesterase)

Question 15

Gi coupled

decrease cAMP

Answer 15

H3

H4

Question 16

M2 agonist

Answer 16

Bethanechol

Question 17

Inhibits 5 lipooxygenase

Answer 17

Zileuton (leukotriene inhibitor)

Question 18

p75 portion of receptor blocks TNF alpha

Answer 18

Etanercept

Question 19

Gq coupled

NO, vasodilation

Answer 19

H1 receptor

Question 20

AChE inhibitor

Answer 20

Neostigmine

Question 21

Stimulates motilin receptors

Answer 21

Erythromycin

Question 22

Presynaptic receptor in the brain

Answer 22

H3

Question 23

Blocks IL-6

Answer 23

Toclizumab

Question 24

Binds to receptor, Prevents binding of IgE

Answer 24

Omalizumab

Question 25

Adalimumab

Answer 25

TNF alpha blocker

Question 26

No antiinflammatory or platelet effects

Answer 26

Acetominophen

Question 27

Most important for platelet aggregation

Answer 27

PGI2 | produced by COX2

Question 28

Inhibits JAK 1+2 more than JAK 3

Answer 28

Baricitinib

Question 29

Inhibits purine synthesis by inhibtin inosine monophosphate dehydrogenase

Answer 29

Mycophenolate mofetil

Question 30

Potent vasoconstriction

Answer 30

TXA2

Question 31

Inhibits JAK 1+3 more than JAK 2

Answer 31

Tofacitinib

Question 32

Muscarinic antagonists (2)

Answer 32

Glycopyrrolate | Dicyclomine

Question 33

Converted to sulfenamide

Answer 33

PPIS | in parietal cell, S-OH binds pump

Question 34

Antacids that produce CO2 and make you burp

Answer 34

Sodium bicarbonate | Calcium bicarbonate

Question 35

Competes with CD28 on T cells to bind to APC CD80 and CD86

Answer 35

Abatacept

Question 36

Certolizumab pegol

Answer 36

TNF alpha blocker

Question 37

Inhibits phospholipase A

Answer 37

Indomethacin