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IP4 > MoA of Cytotoxic Anticancer Drugs > Flashcards

MoA of Cytotoxic Anticancer Drugs Flashcards

1
Q

Mechlorethamine

A

Covalent modifiers of DNA/DNA damaging agent

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2
Q

Melphalan

A

Covalent modifiers of DNA/DNA damaging agent

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3
Q

Bendamustine

A

Covalent modifiers of DNA/DNA damaging agent

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4
Q

Cyclophosphamide

A

Covalent modifiers of DNA/DNA damaging agent

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5
Q

Ifosfamide

A

Covalent modifiers of DNA/DNA damaging agent

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6
Q

Busulfan

A

Covalent modifiers of DNA/DNA damaging agent

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7
Q

Dacarbazine

A

Covalent modifiers of DNA/DNA damaging agent

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8
Q

Cisplatin

A

Covalent modifiers of DNA/DNA damaging agent

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9
Q

Carboplatin

A

Covalent modifiers of DNA/DNA damaging agent

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10
Q

Oxaliplatin

A

Covalent modifiers of DNA/DNA damaging agent

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11
Q

Bleomycin

A

Covalent modifiers of DNA/DNA damaging agent

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12
Q

Doxorubicin

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

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13
Q

Daunorubicin

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

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14
Q

Idarubicin

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

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15
Q

Mitoxantrone

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

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16
Q

Etoposide

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

17
Q

Topotecan

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

18
Q

Irinotecan

A

Topoisomerase inhibitor - poisons activity of topoisomerase to case DNA strand breaks

19
Q

Vinblastine

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

20
Q

Vincristine

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

21
Q

Vinorelbine

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

22
Q

Eribulin

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

23
Q

Paclitaxel

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

24
Q

Docetaxel

A

Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules

25
Ixabepilone
Microtubule inhibitor - interacts with assembly/disassembly of tubulin into microtubules
26
Methotrexate
Antimetabolite - false substrate in folate cycle
27
Pemetrexed
Antimetabolite - false substrate in folate cycle
28
5-fluorouracil
Antimetabolite - false substrate in folate cycle
29
Capecitabine
Antimetabolite - false substrate in folate cycle

IP4 (6 decks)

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