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IP4 > Chemoprotective molecules > Flashcards

Chemoprotective molecules Flashcards

1
Q

Chloride and sodium thiosulfate

A

protects against kidney toxicity from cisplatin

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2
Q

dexrazoxane

A

given with anthracyclines to reduce chronic cardiotoxicity or as an antidote for extravasation

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3
Q

leucovorin

A

given for methotrexate toxicity or as “rescue therapy”, forms N5,N10-methylene THF

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4
Q

Mesna

A

protects against bladder toxicity from acrolein (derived from cyclophosphamide and ifosfamide)

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IP4 (6 decks)

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