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IP4 > AEs of Cytotoxic Anticancer Agents > Flashcards

AEs of Cytotoxic Anticancer Agents Flashcards

1
Q

Bendamustine

A

Myelosuppression

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2
Q

Bisulfan

A

Myelosuppression

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3
Q

Dacarbazine

A

Myelosuppression

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4
Q

Cyclophosphamide

A

generates acrolein (causes hemorrhagic cystitis) and chloroacetaldehyde (causes neurotoxicity and nephrotoxicity)

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5
Q

Ifosfamide

A

generates acrolein (causes hemorrhagic cystitis) and chloroacetaldehyde (causes neurotoxicity and nephrotoxicity)

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6
Q

Cisplatin

A

toxic to kidneys

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7
Q

Carboplatin

A

myelosuppression, some kidney toxicity (less than cisplatin)

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8
Q

Oxaliplatin

A

neurotoxicity

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9
Q

Bleomycin

A

pulmonary toxicity

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10
Q

Doxorubicin

A

acute and chronic cardiotoxicity due to ROS formation, stains bodily fluids red

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11
Q

Daunorubicin

A

acute and chronic cardiotoxicity due to ROS formation, stains bodily fluids red

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12
Q

Idarubicin

A

acute and chronic cardiotoxicity due to ROS formation, stains bodily fluids red

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13
Q

Mitoxantrone

A

stains bodily fluids and skin blue

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14
Q

Etoposide

A

myelosuppression, mucositis

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15
Q

Irinotecan

A

diarrhea

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16
Q

Vincristine

A

peripheral neuropathy, constipation

17
Q

Vinblastine

A

myelosuppression

18
Q

Vinorelbine

A

myelosuppression

IP4 (6 decks)

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