MNT II Test 1 Flashcards
Types of originating tissue
Sarcoma: connective tissue
Carcinoma: epithelial tissue
Causes of cancer
excess energy viruses malignant neplasm radiation limited antioxidants and other nonnurtrients
Medical and Nutritional Mgmt.
Medical - surgery, radiation, chemotherapy, immunotherapy, marrow transplantiation
nutritional - prevent or correct nutritional deficiencies,minimize weight loss, oral feelind , enteral tube feeding, parenteral feeding
Acute vs. palliative vs. hospice care
Acute care: Focus on active
treatment/intervention to cure, alter or prevent
disease &/or to prolong life
Palliative Care: Focus on relief of suffering &
improving the quality of life.
Hospice Care: Focus on relief of suffering &
improving the quality of life
Role of the RD with palliative care
Palliative care may be offered at any time during
illness whereas hospice is usually limited to the
final 6 month of life
Wt. loss: repletion of nutrition stores and
regaining lost wt. may not be reasonable goals
Pressure ulcers: encourage adequate kcal/pro.
Dehydration: hydrate when death is not
imminent
Side effects of chemotherapy
Taste abnormalities that leads to anorexia & constipation Mucositis, cheilosis, stomatitis & esophagitis N/V/D Anemias Depressed immune system Myelosuppression Xerostomia Neutropenia
Radiation therapy and the side effects
cns - acute - fatigue, loss of appetite, elevated blood glucose, - late - headache/lethargy
Head/neck- tongue, larynx, pharynx, tonsils, salivary glands- sore mouth and throat, xerostomia, mocositis, dysphagia, odynophagia
alteration in taste and smell - late effects - mucosal atrophy
thorax - esophagus, lung, breast, acute effects- dysphagia, odynophagia, heartburn fatiuge, loss of appetite , late effects - Esophageal stenosis & necrosis Cardiac: angina Pulmonary: dry cough pneumonitis
Abdomen & pelvis Acute N/V, gastritis Fatigue, loss of appetite Changes in bowel function Late Diarrhea, malabsorption, maldisgestion
Concepts of immunotherapy
Immunotherapy —Flu-like symptoms, decreased food intake, fatigue, chills, and fever Bone marrow transplant (hematopoietic stem cell transplantation(HSCT) —Nausea, vomiting, diarrhea, mucositis, xerostomia, dysgeusia Severe oral muscositis Graft versus host disease (GVHD) Veno-occlusive disease (VOD)
Bone marrow transplant (implications/complications)
Bone marrow transplant (hematopoietic stem cell transplantation(HSCT) —Nausea, vomiting, diarrhea, mucositis, xerostomia, dysgeusia Severe oral muscositis Graft versus host disease (GVHD) Veno-occlusive disease (VOD)
Medical and Nutrition management of marrow transplantation
medical
pretransplantation postransplantation
antiemetics antibiotics/blood products
nutritional pretransplantation bland liquids and soft solids salivary stimunlants and substitutes sauces and gravies with food
postransplantation
nutritional support
enteral or tpn
meet increased energy and protien needs
Neutropenia (neutrophil counts & neutropenic diet)
Neutropenia: a reduction in WBC count
(neutrophils) that can be caused by
chemotherapy or radiation therapy.
Can result in increased susceptibility to
potentially life-threatening infections.
Neutropenic precautions
Instituted when absolute neutrophil count drops
<1500/mm3
Food safety is important. See pg. 745 Escott-Stump for
tip
Immune system compromise
Avoid all fresh foods (raw meat, moldy foods,
unpasteurized beverages)
See Table 13-10 (Nutrition & Diagnosis)
Neutropenic Diet Guidelines
Surgery sites and related effects
Site Effect Head/Neck Chewing/swallowing Gastrectomies Total: Malabsorption & fat intolerance Partial: if is in the lower remnant part of the stomach: Dumping Syndrome Pancreas
70% resection: Insulin and CHO controlled diet 90% resection: Insulin, CHO controlled diet and pancreatic enzymes replacement
Partial & total Intestinal Tract
Resections Large losses of fluid and
electrolytes
Cancer cachexia – characteristics & etiology
Cachexia Kakos: bad Hexis: condition Inadequate energy intake Increased energy expenditure Metabolic changes induced by the tumor itself.
It is a syndrome characterized by severe weight loss,
muscle wasting, anemia and anorexia.
Factors that affect appetite
intermidiary metabolites nutritional abnomalities neurologic influences psychological influences endocrine abnormalites secondary infections malignant lesions medication cytokines
Medications that may be useful for cachexia and weight loss
Appetite stimulants
Metabolic agents and cytokine blockers
Prokinetic drugs
Anabolic agents
Purpose of MNT
To prevent or correct nutritional deficiencies,
Minimize wt. loss
Treat the side effects
Treatments for Nausea, vomiting and diarrhea
Seratonin antagonists (Zofran)
Corticosteriods (Decadron, Prednisone)
Non-medication: acupressure, massage, hypnosis
& diet modification, ginger
Frequent small meals, timing of meals
Treatments of symptoms (dysgeusia, xerostomia, esophagitis, stomatitis, mucositis, constipation, early satiety)
Dysgeusia Increase flavoring and seasonings Xerostomia Artificial saliva Suck in hard candy and/or ice Soft/Bland diet Cold foods, no rough and salty foods
Nutritional recommendations (be able to calculate needs) Protein & calories
Protein: (g/kg)
0.8-1.0 for normal maintenance
1-1.2 for non stressed patient
1.2-1.6 for hyper-catabolic patient
1.5-2.5 for severely stressed patient
1.5-2.0 for hematopoietic stem cell transplant patient
Caloric Needs
Harris Benedict plus injury factor between 1.1-1.6
depends the severity
Other such are Mifflin-St Jeor or Ireton-Jones
formula can be used.
Per Krause: pg. 842
25-30 kcal/kg – normometabolic
30 – 35 kcal/kg – hypermetabolic, stressed, BMT
30 – 40 kcal/kg/day – nutritional repletion, wt gain
AICR recommendations
Be as lean as possible without becoming underweight.
Be physically active for at least 30 minutes every day.
Avoid sugary drinks. Limit consumption of energy-dense foods.
Eat more of a variety of vegetables, fruits, whole grains and legumes such as beans.
Limit consumption of red meats (such as beef, pork and lamb) and avoid processed meats.
If consumed at all, limit alcoholic drinks to 2 for men and 1 for women a day.
Limit consumption of salty foods and foods processed with salt (sodium).
Don’t use supplements to protect against cancer.
* It is best for mothers to breastfeed exclusively for up to 6 months and then add other liquids and foods.
* After treatment, cancer survivors should follow the recommendations for cancer prevention.
Inhibitors & enhancers of carcinogens
Inhibitors of carcinogens Antioxidants Vitamin C, E, selenium, & carotenoids Phytochemicals Anthrocyanins, & lycopene Enhancers of carcinogens Fat in red meat Grilling of meat at high temperatures
Nutritional Factors for cancer prevention
Fat
High consumption of red meats & high fat dairy products
Protein
Avoid foods high in fat (esp. those above)
Plant based proteins = protection
Soy & phytoestrogens
Protective prior to adulthood for women
Should be limited though for women with breast cancer
Who is at higher risk of contracting the HIV virus
~1 in 4 new infections is among 13 – 24 year olds Stable increase at about 50,000 new /year in US African Americans increasing disproportionately(44% of new cases in 2010)
Cells that are affected by HIV
HIV invades the genetic core of the CD4
cells, (T-helper lymphocyte cells)