Mixed/Radiopaque Non-Odontogenic Lesions Flashcards

1
Q

Benign fibro-osseous lesions

A

Mixed/Radiopaque Non-Odontogenic Lesions

  • Group of benign neoplasms & non-neoplastic lesions of bone w/ similar microscopic features; growth is altered, bone gets taken up and replaced w/ fibrous tissue and makes its own bone
  • Cemento-osseous dysplasia: Not a neoplasm
  • Ossifying (cementifying) fibroma: Neoplasm
  • Fibrous dysplasia: Not a neoplasm
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2
Q

Cemento-Osseous Dysplasia

A

Mixed Non-Odontogenic Lesions

  • Develop in areas of teeth but may represent benign fibro-osseous lesions
  • Not neoplasms - Benign self-limiting growth disturbances of bone
  • Asymptomatic
  • Do not cause enlargement, rarely tooth resorption
  • Replacement of normal bone w/ cellular fibrous CT, then replacing w/ disorganized bone/cementum
  • 90% in middle aged females 30-50yo
  • Cellular fibrous tissue w/ formation of cementum & bone
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3
Q

What are the three types of Cemento-Osseous Dysplasia?

A

Mixed Non-Odontogenic Lesions

  • Periapical Cemento-Osseous Dysplasia
  • Focal Cemento-Osseous Dysplasia
  • Florid Cemento-Osseous Dysplasia
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4
Q

Periapical Cemento-Osseous Dysplasia

A

Mixed Non-Odontogenic Lesions

One of the types of Cemento-Osseous Dysplasia

  • Multiple PA lesions involving MN anteriors
  • More common in AAs
  • May produce mineralized pdt
  • Surrounded by thin RL line
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5
Q

Of the three types of Cemento-Osseous Dysplasia, which is the most common?

A

Mixed Non-Odontogenic Lesions

Focal Cemento-Osseous Dysplasia

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6
Q

Focal Cemento-Osseous Dysplasia

A

Mixed Non-Odontogenic Lesions

One of the Cemento-Osseous Dysplasias

  • Same features as PCOD (mutliple PA lesions involving MN ant)
  • May produce mineralized pdt
  • Surrounded by thin RL line
  • Occurs in only 1 location other than MN ant
  • Most common
  • Usually in posterior MN
  • More common in Caucasians
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7
Q

Florid Cemento-Osseous Dysplasia

A

Mixed Non-Odontogenic Lesions

One of the Cemento-Osseous Dysplasias

  • Same features as PCOD
  • Occurs in 2+ quadrants
  • More common in AAs
  • Multiple, bilateral RL-RO lesions throughout the jaws
  • Multiple PA RL areas w/ formation of mineralized pdt
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8
Q

Cemento-Osseous Dysplasia: Tx

A

Mixed Non-Odontogenic Lesions

  • After dx, no additional tx - for all Cemento-Osseous Dysplasia types
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9
Q

Central Ossifying Fibroma

A

Mixed Non-Odontogenic Lesions

  • True neoplasm of bone ⇒ persistent & progressive growth; must be removed
  • Grows slowly; can cause bony expansion and displacement of teeth
  • Growth of bone PLUS fibrous tissue
  • Appears at wide age range
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10
Q

Central Ossifying Fibroma: Rad

A

Mixed Non-Odontogenic Lesions

  • Well-defined borders and RO foci
  • Causes expansion and slowly growing
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11
Q

What other two conditions are difficult to differentiate microscopically from Central Ossifying Fibroma?

A

Mixed Non-Odontogenic Lesions

  • Cemento-Osseous Dysplasia
  • Fibrous Dysplasia
  • Central Ossifying Fibroma
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12
Q

Central Ossifying Fibroma: Tx

A

Mixed Non-Odontogenic Lesions

  • Enucleation or curettage
  • Usually slow growing but can become large if untx’d
  • Low recurrence rate
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13
Q

Radiopaque Non-Odontogenic Lesions

A
  • Fibrous Dysplasia
  • Idiopathic Osteosclerosis
  • Osteoma
  • Mucositis
  • Sinusitis
  • Mucous Retention Pseudocyst
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14
Q

Fibrous Dysplasia

A

Radiopaque Non-Odontogenic Lesions

  • Non-neoplastic developmental disturbance of bone growth
    • Bone ⇒ Fibrous tissue
  • GNAS gene
  • Severity of disease depends on stage of development that mutation occurred
    • Mutation happening later but before 20yo = monostotic b/c only one bone is affected genetically
      • Most common
    • Mutation happening earlier in life = polyostotic b/c many bones are affected
      • Skin and bone
  • Stops growing when bones do and then we can recontour back to normal
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15
Q

Two types of Fibrous Dysplasia

A

Radiopaque Non-Odontogenic Lesions

  • Monostotic: Only one bone
    • Begins in 1st & 2nd decades of life - always before 20yo
    • More common than PFD
    • Involvement of MN leads to expanion of both buccal & lingual plates
  • Polyostotic: Multiple bones
    • Begins early in life
    • Systemic features
    • Very rare
    • Jaffe Syndrome
      • Involves fewer bones
      • Cafe-au-lait melanotic macules
    • McCune-Albright Syndrome
      • ​Involves most of the skeleton
      • Endocrine abnormalities; precocious puberty in females
      • Cafe-au-lait macules
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16
Q

Fibrous Dysplasia: Microscopic Features

A

Radiopaque Non-Odontogenic Lesions

  • Features of fibro-osseous lesion: Fibrous CT and trabeculae of bone
  • Can’t be separated from Ossifying (Cementifying) Fibroma on basis of microscopic features
17
Q

Fibrous Dysplasia: Tx

A

Radiopaque Non-Odontogenic Lesions

  • Dx requires clinical & radiographic information
  • Bony contouring after lesion stops growing - if it is a cosmetic problem
    • Usually stops growing when bones stop growing
  • Good px
  • Lesions should NOT be irradiated bc it might cause malignant transformation
18
Q

Idiopathic Osteosclerosis

A

Radiopaque Non-Odontogenic Lesions

  • AKA Dense Bone Island, Enostosis, Bone Whorl
  • Intraosseous counterpart to exostosis/tori
    • Focal area of increased radiodensity
  • Bone thicker and denser and we don’t know why
  • Very common
19
Q

Other names for Idiopathic Osteosclerosis

A

Radiopaque Non-Odontogenic Lesions

  • Dense Bone Island
  • Bone Whorl
  • Enostosis
20
Q

Idiopathic Osteosclerosis: Dx

A

Radiopaque Non-Odontogenic Lesions

  • Dx can be made w/ rads alone
    • Biopsy considered only if there are symptoms, continued growth or cortical expansion
21
Q

Osteoma

A

Radiopaque Non-Odontogenic Lesions

  • Benign tumor of bone restricted to craniofacial skeleton
    • Composed of mature compact or cancellous bone
  • Tori and exostoses are not considered osteomas
  • Periosteal: Surface of bone
  • Endosteal: Medullary bone
  • Osteoma cutis: W/in muscle or dermis
  • Condyle: Osteomas of condyle can lead to a shift in the pt’s occlusion
    • Deviation from midline and x-bite
  • Youn pts
22
Q

Osteoma: Rad

A

Radiopaque Non-Odontogenic Lesions

  • Well-circumscribed
  • Not really corticated bc so RO
23
Q

What lesions may small osteomas appear very similar to?

A

Condensing osteitis

Idiopathic osteosclerosis

24
Q

Osteoma: Tx

A

Radiopaque Non-Odontogenic Lesions

  • Observe (small & asymptomatic)
  • Surgery (symptomatic & deforming)
  • Lesions causing symptoms or deformities are conservatively excised
  • Small lesions can be observed periodically
  • Lesions in condyle usually require removal
  • Paranasal lesions may req excision if symptomatic
  • Entirely benign
25
Q

Mucositis/Sinusitis

A

Radiopaque Non-Odontogenic Lesions

  • Inflammatory disease of the sinus
  • Epithelium thickens bc it is inflamed and then we can see it radiographically
  • Generally follows contour of the floor
  • Mucositis: Regional; Focal in one sinus
    • Inflammation of the sinus lining
    • Allergy, irritation, foreign body, trauma
    • Typically asymptomatic
    • Well defined, non-corticated, RO band of increased radiopacity paralleling the bony wall of the MX sinus
  • Sinusitis: Generalized in both sinuses
    • Allergen, bacteria, or virus
    • Pain, pressure, swelling over area of sinuses
    • May manifest as tooth pain
    • May have associated discharge
26
Q

Mucositis/Sinusitis: Tx

A

Radiopaque Non-Odontogenic Lesions

  • Mucositis: No tx needed
  • Sinusitis: Control infection, relieve pain, surgery
27
Q

Mucous Retention Pseudocyst

A

Radiopaque Non-Odontogenic Lesions

  • Blockage of seromucous glands in sinus mucosa
  • Submucosal accumulation of secretions = dome-shaped swelling
  • Well-defined, corticated, smooth, dome-shaped, sessile RO mass
  • Asymptomatic
  • No tx necessary
28
Q

What are Mixed Non-Odontogenic Lesions?

A
  • Cemento-osseous Dysplasia
  • Central Ossifying Fibroma
29
Q

What are RO Non-Odontogenic Lesions?

A
  • Fibrous Dysplasia
  • Idiopathic Osteosclerosis
  • Osteoma
  • Mucositis/Sinusitis
  • Mucous Retention Pseudocyst