Mixed PT questions Flashcards

1
Q

Delirium mangement in Parkinson’s

A

-haloperidol 0.5 mg as the first-line sedative in NON PARKINSONS PATIENTS

-antipsychotics can often worsen Parkinsonian symptoms: atypical antipsychotics quetiapine and clozapine are preferred or lorazpam

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2
Q

Causes of polyuria

A

-diuertics, alcohol, caffeine
-DM
-lithium
-heart failure
-hypercalcaemia
-hyperthyroidism
-hypokalaemia

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3
Q

Diabetes insipidus

A

-Decreased secretion of antidiuertic hormone (ADH) from pituitary (cranial) or insensitivity to ADH (nephrogenic)

-causes: idiopathic, TBI, pituitary surgery, haemochromatosis, hypercalcaemia, hypokalamia, lithium (desensitises the kidney’s ability to respond to ADH in collecting ducts)

-SX: polyuria, polydipsia

-Ix: water deprivation test (high plasma osmolality and low urine osmolality)

-Mx: central DI: desmopressin
Nephrogenic: thiazides and low salt diet

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4
Q

How to reverse dabigatran (direct thrombin inhibitor)

A

Idarucizumab

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5
Q

Pneumothorax mangement

A

minimal symptoms as ‘no significant pain or breathlessness and no physiological compromise’
no or minimal symptoms → conservative care, regardless of pneumothorax size
symptomatic → assess for high-risk characteristics

high-risk characteristics are defined as follows:
haemodynamic compromise (suggesting a tension pneumothorax)
significant hypoxia
bilateral pneumothorax
underlying lung disease
≥ 50 years of age with significant smoking history
haemothorax
if no high-risk characteristics are present, and it is safe to intervene, then there is a choice of intervention:
conservative care
ambulatory device
needle aspiration
if high-risk characteristics are present, and it is safe to intervene → chest drain

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6
Q

Most common form of inherited cancer

A

hereditary non-polyposis colorectal carcinoma (HNPCC, Lynch syndrome 5%)
high risk of endometrial cancer too

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7
Q

Bell’s palsy mangment

A

Oral prednisolone 10 days + eye care (artificial tears + eye lubricants)

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8
Q

Oesophageal adenocarcinoma risk factors

A

Usually found in the lower third near gastrooesophageal junction (oppose to squamous)
GORD
Barrett’s
Smoking/obesity
Mx: surgical resection

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9
Q

Crohn’s maintainence of remission

A

1st line: azathioprine or mercaptopurine (immunosurpressants)
2nd line: methotextrate
3rd line: Infliximab

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10
Q

Most appropriate screening for diabetic neuropathy

A

Test sensation using 10g monofilament

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11
Q

ACEi common side effect

A

Cough

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12
Q

MI Complications

A

-VSD: pansystolic murmur + HF sx
-Rupture/ischaemia of pap muscle: early to mid systolic murmur acute mitral regurg
-left ventricular free wall rupture: 1-2 weeks after MI, acute HF secondary to cardiac tamponade
-Dressler’s- central pleuritic chest pain (pericarditis) 2-6 weeks post MI

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13
Q

Soft S2

A

Aortic stenosis

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14
Q

Blood pressure target >80

A

145/80

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15
Q

Moderate vs Severe vs Life-threatening Asthma

A

Moderate: PEFR 50-75% best or predicted, Speech normal, RR < 25 / min, Pulse < 110 bpm
Severe: PEFR 33 - 50% best or predicted, Can’t complete sentences, RR > 25/min, Pulse > 110 bpm
Life-threatening: PEFR < 33% best or predicted, Oxygen sats < 92%, Silent chest, cyanosis or feeble respiratory effort, Bradycardia, dysrhythmia or hypotension, Exhaustion, confusion or coma

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16
Q

CHA2DS2-VASc score

A

0 No treatment
1 Males: Consider anticoagulation
Females: No treatment (this is because their score of 1 is only reached due to their gender)
2 or more Offer anticoagulation
Warfarin or apixaban/ dabigatran

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17
Q

V1-6, I, aVL ischeamic changes

A

left anterior descending

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18
Q

Statin adverse effect

A

Myopathaties: i.e. myositis, myalgia etc

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19
Q

S3 and S4 causes

A

S3: constrictive pericarditis, left ventricular failure and mitral regurg
S4: Aortic stenosis, HOCM, HTN

20
Q

Slow rising pulse vs collapsing pulse vs narrow pulse

A

Slow rising/plataeu or narrow: aortic stenosis
Collapsing: aortic regurg

21
Q

Propanolol contraindication

A

concurrent verapamil use (CCB) can cause severe bradycardia

22
Q

loud S1, split S2 and a diastolic murmur

A

Mitral stenosis

23
Q

Loop diuretics SE

A

Ototoxicity

24
Q

Long term antiplatlets

A

STEMI: aspirin (lifelong) + tricagrelor (12m)
TIA: clop (lifelong)
Ischaemic stroke: clop (lifelong)
Peripheral arterial disease: clop (lifelong)

25
Q

Dry cough and atypical chest signs, hyponatraemia and lymphopenia

A

Legionella pneumophilia- erythromycin

26
Q

short QT interval

A

Hypercalcaemia

27
Q

Asthma drug contraindications

A

beta blockers and adenosine

28
Q

theophylline MOA

A

phosphodiesterase competitive inhibitor preventing cAMP breakdown

29
Q

digoxin toxicity

A

short QT interval
inverted T waves
ST depression
prolonged PR interval

30
Q

AF examination finding

A

pulse irregularly irregular

31
Q

Angina Mx

A

GTN
Beta blocker (CCB if contra)
3rd line : if CCB is not erliving long acting nitrate e.g. ivabradine or isosorbide mononitrate

32
Q

Granulomatosis with polyangiitis

A

Autoimmune resp tracts + neph
Sx: sinutitus, epistaxis/haemoptysis, SOB
cANCA, cavitating lesions

33
Q

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

A

Asthma, eosinophilia, SOB
pANACA

34
Q

Hepatic encephalopathy Mx

A

Lactulose first line with rifaximin for prophylaxsis

35
Q

Rosacea

A

Nose, cheeks, forehead:
flushing, telangiectasia and persistent erythema with papules and pustules (sunlight may exacerbate)
papules: topical ivermectin

36
Q

what is hCG secreted by

A

syncytiotrophoblast, detectable 8 days after conception

37
Q

Boerhaave syndrome

A

Transmural oesophageal perforation: vomiting
severe chest pain/shock
suprasternal crepitus (subcutaneous emphysema)

38
Q

Blood film: hypersegmented polymorphs

A

Megaloblastic anaemia- B12 deficiency, investigation: intrinsic factor

39
Q

Hypercalcaemia sx

A

‘bones, stones (renal), groans (abdo) and psychic moans’
corneal calcification
shortened QT interval on ECG
hypertension

40
Q
A
41
Q

Common pneumonia cause after influenza infection

A

Staph Aureus
Mx: fluclox + amoxicillin

42
Q

Alzheimer’s drugs

A
  1. 1st line: donepezil (acetylcholineesterase inhibitor)
  2. 2nd line: memantine (NMDA receptor antagonist)
43
Q

Febrile convulsion

A

Seizures provoked by fever in children between 6 months - 5 years
If recurrent benzodiazepine rescue may be used i.e. rectal diazapam or buccal midazolam

44
Q

Dix Hallpike/Epley manoeuvre

A

Dix-Hallpike: diagnostic of BPPV
Epley: treatment of BPPV

45
Q

Nephrotic syndrome vs nephritic syndrom

A

Nephrotic: proteinuria, hypoalbuminaemia, oedema

Nephritic: haematuria (red cast cells), proteinuria, hypertension, oliguria

46
Q

Hypoglycaemia Mx

A

Oral glucose 10-20g liquid, tablet or gel

47
Q

Cerebellar stroke sites

A

Anterior: legs
Middle: arms
Posterior: eyes