Mixed/Formatives etc Flashcards
Low impact tauma in old people, crescent shaped hypodensity on CT
Subdural haemorrhage
Man falls off horse, lucid interval, hyperdense biconvex on CT
Extradural haemorrhage
Huntington’s triple repeat of….
Glutamate
Two year slow onset of Parkinsonism, mainly affecting gait and lower limbs with no autonomic dysfunction
Vascular parkinsonism
What does LOAF stand for?
Lateral two lumbricals
Opponens pollicis
Abductos pollicis brevus
Flexor pollicis brevis
Fried egg frontal lobe brain tumour, presents with seizures and headache in a child
Oligodendrocytoma
Immediate management of TIA 3h ago if symptoms are now resolved
Aspirin 300mg
- don’t CT it won’t pick up, wait until spec clinic for MRI)
PLS affects which motor neurons
UMN
PMA affects which motor neurons
LMN
First synapse in somatosensory pathway of ST tract
Lumbar spinal cord
Function of vestibulospinal tract
Activates the antigravity extensory muscles
- extensor mechanism prevents you falling
Fixed dilated pupil, head trauma, unilateral descending tentorial herniation
Uncal herniation
Management of LEMS
3, 4- diaminopyridamine (no steroids involved)
Management of absencse seizure
Ethosuximide or valproate
Name an antidepressant used to block SSRI side effects
Mirtazapine
Schizophrenic symptoms from childhood, lack of close friends and severe social anxiety
Schizotypal personality disoorder
Depression, anxiety, irriability, physial health hanges e.g. chest rash
Substance misuse (consider if MH symptoms + physical symptoms)
Management of psychosis in PD
Atypical antipsychotics e.g. olanzapine
Management of delirium in PD
Lorazepam
Investigation for parkinsonism with dementia or LBD
CT
- DaT scan them if CT doesn’t show anything
Medical management of PTSD
Sertraline or venlafaxine
Biggest risk factor for puerperal psychosis
Bipolar disorder
Characteristic sign of SVT on ECG
<120ms QRS complexes
First line management of ectopic
IM methotrexate
First line inv of endometriosis
TVUS
Management of urge incontinence
Oxybutynin or mirabegron
Pain before period, sore pooping, tender nodular mass on pelvic exam
Endmetrial cysts
3rd line PET management
Methyldopa
First line inv for secondary amennhorroea
Urine beta hCG
Management of complete molar pregnancy
Surgical removal and send tissue for pathology
Pt comes in looking for a new contraception 2 days PP, she has BMI 41 and her partner has a vasectomy booked
Progesterone only pill
- don’t give long term due to vasectomy
- don’t give COCP due to weight
Ovarian tumour with transitional cels, coffee bean nuclei and fibrous stroma
Brenner
- comes from bladder
Hormone inhibiting contractility in late pregnancy
Progesterone
Hormone increasing contractility in late pregnancy
Oestrogen
Hormone increasing contractions and excitabilit and producing prostaglandins in late pregnancy
Oxytocin
Where should quinsy pts be treated?
Admit to hospital, risk of airway compromise
Imaging choice for kidneys specifically PCKD
US
Management of AKI in burns patient
Fluid challenge with crystalloid
Components of tetralogy of fallot
Pulmonary stenosis
VSD
Right ventricular hypertrophy
Overriding aorta
Can NPH present with tremor as well as triad?
Yes
Why do you get pink urine in G6PD?
Intramedullary cause of haemolysis
- therefore you get breakdown products in the urine e.g. haemoglobinuria
Prophylactic therapy for polycythemia vera
Aspirin
- due to risk of thrombosis
Arterial thrombosis stroke, 3 miscarriages, FHx early death, prolonged PT and APTT
Antiphospholipid
Elderly male with uncomplicated UTI who is penicillin allergic
Cotrimoxazole
What UTI abx given in 1st and 2nd trimester?
Nitrofurantoin
What UTI abx given in 3rd trimester?
Trimethoprim
Lumbar puncture in meningitis?
NOOOOO
- due to incr risk of raised ICP and coagulopathy
Which hormone gives negative feedback to hypothalamus during follicular phase?
Oestrogen
What happens to steady state plasma conc when you double the rate of admin of a FOK drug?
Steady state plasma conc doubles
What cells incr membrane resistance in central nervous system?
Oligodendrocytes
What is next step management in triple neg breast cancer pt who has had WLE and SNB?
Radiotherapy
- unless maybe there was cancer left behind in nodes not sure
Investigation for male breast lump
US
- due to dense breast tissue
- may go on to do biopsy/mammo etc
What’s the underlying mechanism behind urge incontinence in old female pt with Hx T2D?
Detrusor muscle overactivity
- T2D related bladder atony would cause stress like symptoms and dribbling
Contraindication to progesterone only implant
Active breast cancer
Wells score >4, what’s the first line investigation?
Urgent CTPA
Episodes of blacking out with strong family history incl sudden death and ECG changes
Brugada syndrome
Best way to analysea 16 gene panel for long QT
Whole genome/exome sequencing
- looking for point mutation in muliple genes
What can you detect in chromosomal microarray?
Copy Number Variations (CNV)
80 yo with hot tender breast and overlying cellulitis with no response to 2 courses of abx
Inflammatory breast cancer
- urgent 2ww to breast clinic
What type of stricture is specific to Crohn’s?
Ileal stricture
Management of acute liver failure with neutrophilic ascitic tap in alcoholic?
Broad spectrum abx
- to mange the bacterial peritonitis
- can’t give emergency liver transplant due to active alcoholism
Red jelly sputum pneumonia post-op for bowel obstruction in CF pt
Klebsiella pneumonia
- klebs is a gut commensal