Mixed Flashcards
STEMI
<90 mins: PCI
If not feasible: Thrombolytic Rx
Contraindications for Thrombolytic rx
Previous ICB
BP > 180/110
Recent major surgery
Aboriginal ( Antibody+ to streptokinase)
Dual antiplatelet duration post PCI
12 months
Prognostic FX for systolic heart failure
Raised JVP+ S3 gallop
Microangiopathic hemolytic anemia
Indirect bilirubin
Decreased haptoglobin
LDH elevated
Schistocytes on PBS
HUS
Shiga toxin
Renal symptoms predominant with microangiopathic hemolytic anemia
von Wiilebrand disease
Autosomal dominant
Bleeding 🩸 time increased
Normal platelet
vWF Ag: low in type 1
PTT normal/high
vWD rx
DDAVP
Factor VIII 8 concentrate
Platelet transfusion only in severe cases
Best initial study for oropharyngeal/motility related dysphagia
Barium study
Hypocalcemia Mx
Based on symptoms √
•sympromatic : IV Calcium gluconate
Based on levels ✓
•less than 1.9 : IV Ca gluconate
> 1.9: oral calcium+ vitamin D
SCFE
Rx
Stop weight bearing
Gentle reduction with pinning
Cocaine vs smoking
Effects on foetus
Cocaine No anomaly but IVH
Smoking cause anomalies such as IUGR, GI malformations
Postural hypotension
Test
Initial supine and standing BP:
Less than 10 bpm increased and hypotension: autonomic
+ table tilt test
> 30bpm and hypotension: hypovolemia
> 30bpm increased, NO hypotension: POTS
Commonest cause of obstructive jaundice
Stone
Periampullary Tumor: head of the pancreas commonest
Strictures
Open wound #
CARATXO
Clean wound
Analgesia
Reduction by traction
Antibiotics
Tetanus prophylaxis
Xray
Operation theatre
OCP with antiepileptics
Stop the OCP and use condom
IUCD or Depot MPA
If refused to discontinue OCP:
✓Increase the dose
✓Tricycle phase
Implanon, ocp
Not advised for patients on antiepileptics as it’s enzyme inducers
GBS bacteruria
Vs GBS vaginal swab
Bacteruria:Needs treatment (by order wise)
Cephalexin
Nitrofurantoin
Augmentin
Vaginal: normal colonisation, no need Rx
GBS bacteruria but asymptomatic
Asymptomatic bacteruria needs Abx!!!
AV block
1: constant pr
2: type 1: pr longer longer drop
Type 2: pr constant & drop
3 constant P-P and constant Q-Q
VT pulse +
Hemodynamic unstable
Cardioversion
JVP normal physiological response
Expiratory: rise
Inspiration: drop
Pericarditis
Reverse in JVP, expiratory: drop inspiration: rise Kussmaul sign
Pericarditis
ECG ∆
Diffuse ST elevation
Pr depression in lead 1 especially
TCA toxicity
Widening qrs complex
Prolonged qt
Kussmaul sign
Seen in constrictive pericarditis
✓JVP reversed
✓Edema
✓Congestive hepatomegaly
✓Ascites
Patient missed his CHF medications, comes back with hypervolemic sx
Initial: ace (-) to reduce after load
Diuretics to improve symptoms
NOT to give beta blockers yet. To be given once euvolemic only
EF reduced/ systolic dysfunction
Hypervolemic
Ace -/ARB
MRA
EF reduced/systolic dysfunction
Euvolemic
Ace (-) / ARB
Diuretics or MRA
B- blockers
Preserved EF/diastolic dysfunction
Beta blockers
CCB
Diuretics: in congestion cases
HOCM
Echo 1st
Rx: beta blockers + verapamil+ dispyramide
Catheter with alcohol to infarct septum
Bradycardia
Asymptomatic: reassurance
Symptomatic: initial: IV atropine 1st line 0.6 mg then 0.5mg every-5 mins
IV adrenaline infusion: 2nd line
In ED: temporary pacing with percutaneous or IV pacemaker
Elective permanent pacemaker later
AV block
Best initial
Transcutaneous Pacing
PSVT symptomatic young man
1st choice: adenosine
2nd: verapamil
3rd: beta blockers
AF Stable without decompensated HF:
Beta blockers 1st choice
Add Digoxin of not well controlled
Flecainide for rhythm control
AF with decompensated HF
Digoxin initial choice
Avoid beta blockers !!!
AAA surveillance
3-3.9 : 24 mth
4- 4.5: 12 mth
4.6- 5: 6 mth
> 5: 3 mth
AAA indication for surgery
> 1cm /year
Male> 5.5
Female> 5.0
Symptomatic
Thoracic> 6.0
Acute limb ischemia
Most common Cause?
Thrombosis
Acute limb ischemia
Post embolectomy mx
Heparin initiated, then bridging with Warfarin. Once INR of 2-3 achieved, omit heparin
Warfarin for 6 months
*Cardiac origin emboli needs lifelong treatment
Perioperative high mod low risk for VTE prophylaxis
Q142
Medical high risk: CASHSTD
AF asymptomatic
Aspirin 1st
CHA2DS2 VASc
For Warfarin or NOAC if =/>2
Others eg b blockers if Symptomatic
Ace (-) , smoking cessation, statin
ABI< 0.9
For <0.4 : urgent referral to vascular
Dazzling with sunlight
Cataract
Needle stick injury
Patient status unknown
Medical personnel not immunised
Ivig+ 3 dose hepatitis B vaccine
Colonoscopy
Asymptomatic
Cat 1: ifobt every 2 yrs from 45
Cat 2: ifobt every 2 yrs from 40
Cat 3: ifobt every 2 yrs from 35
Cat 2
Cat 3
Asymptomatic
Colonoscopy every 5 yrs
Low dose aspirin
Definition of category in colon cancer
Cat 1 ✓1fdr or 1 FDR +;1 SDR> 55
Cat 2 ✓1fdr <55 or 2 FDR any age
✓1fdr +2fdr any age
Cat. ✓3fdr or 3sdr ( at least 1 before 55)
Parvovirus monitoring in exposed pregnant women
IgG and IgM
If both negative: repeat in 2 weeks
IgG+ IgM - : immune mother ,no need follow up
IgG - IgM + :infected
IgG + IgM+ : recent infection
Parvovirus+
1-2 weekly USG for 6-12 weeks look for hydrops
If seen, for umbilical cord sampling and intrauterine blood transfusion may be required
Hemochromatosis
Ix
Iron studies: high ferritin, high transfering saturation> 50%
If 1° : gene studies: HFE gene testing
Liver biopsy or CT scan ( Ferriscan) : iron deposits seen
Hemochromatosis
Rx
Phlebotomy: weekly then 4l3-4 monthly
✓done prior to liver cirrhosis, good outcome
Lithium
Action
Cautions:
Modulation of phosphoinostitol pathway
Nephrogenic DI, thyroid, CKD , Ebstein anomalies