Mitral and Tricuspid Valve Disease Flashcards
Mitral valve anatomy
- Annulus - ring:helps seat the valve
- Leaflet
- Chordae
- Papillary muscle - Anchor into myocardium
Role of mitral valve
Opens in diastole, allow blood to flow from LA to LV
Closes in systole to prevent blood from flowing backwards from LV to LA
Main etiologies of mitral stenosis (MS)
MAINLY Rheumatic MS (80-99%), only 1/2 report rheumatic fever Calcific MS (3%), advanced age & renal disease
Jones criteria (how many major and minor?)
2 major or 1 major + 2 minor -> high risk
Clinical presentation of mitral stenosis (6)
- Dyspnea
- Hemoptysis
- Pulmonary hypertension/CHF
- Right sided heart failure (edema, ascites)
- Atrial fibrillation (because of LA dilation)
- Thromboembolic event - stroke (because stagnant blood in LA leads to clot formation)
Physical exam findings of mitral stenosis
Loud S1: High AV pressure keeps MV open until ventricular systole forcefully closes valve
Snap: Follows S2, due to opening of stenotic leaflets (hearing it open!) Can assess severity by listening to timing of snap - inversely proportional. Higher LA pressure forces valve to open earlier
Diastolic rumble: Low frequency decrescendo murmur due to turbulent flow across stenotic valve during diastole.
Pulm hypertension physical exam (4)
- Loud P2
- RV thrill or lift
- JVD
- Tricuspid regurg
EKG findings for MS
- Left Atrial Enlargment
- RVH if pulm hypertension exists
- Possible atrial fibrillation
ECHO findings for MS (4)
- Left atrial enlargement
- Restricted opening of MV in diastole
- Thickened mitral valve leaflets, fusion of commissures
- MS severity estimated by Doppler or direct visualization
Drug Tx for MS
- MOST IMPORTANT: Beta blockers slow HR and allow more time for blood to cross the MV in diastole
- Diuretics to treat CHF symptoms
- Anticoagulants if aFib is present (MV can cause stasis)
Mechanical Tx for MS
- Mitral valve replacement (biprosthetic or mechanical valves)
- Percutaneous Ballon Miral Valvuloplasty
Indications for intervention of MS
- Symptoms
- Atrial Fib
- Pulmonary hypertension
What is mitral regurgitation? What causes it?
Inadequate mitral valve closure such that blood flows backwards, from the LV to the LA during systole
Mitral valve prolapse is the most common cause of primary mitral regurg.
May be caused by abnormality of any of the components of the MV anatomy
Etiology of mitral regurgitation
- Myxomatous degeneration: MV prolapse
- Ischemic heart disease: papillary muscle dysfunction or rupture
- Endocarditis: valve deformity, perforation
- Rheumatic valve disease
- LV enlargement: stretches mitral annulus and/or papillary muscles
What physical exam finding do you have for mitral regurgitation?
Holosystolic murmur best heard at apex with radiation to the axilla