mitosis and meiosis tonight Flashcards
what is independent segregation/ assortment?
occurs In metaphase 1
maternal and paternal chromosomes can be positioned either side of the equator of the cell
This is random and independent for each homologous pairs
results in cells with different combinateation od maternal and paternal chromosomes
What happens in telophase
chromosomes uncoil/ decondense and nuclear envelope reforms around DNA
what happens in metaphase 2?
chromosomes line up at the equator of cell and attach to spindle fibres by the centromere
what happens in prophase 2
chromsomes condense and become visible
spindle fibres form
what happens in the S phase of mitosis
DNA replication
what happens in prophase 1
chromosomes condense and become visible,
homologous chromosomes attach to each other at chiasmata ( non sister chromosomes join together)
forming bivalents spindle fibres form
what happens in prophase
chromosomes condense and become visible due to DNA becoming associated with histones, nuclear membrane and nucleolus disappears, spindle fibres start to form
what happens in telophase 1
chromosomes uncoil
spindle fibres break down
haploid nuclei have formed
How does meiosis increase genetic variation
independent segregation/ assortment
and crossing over
increasing combination of alleles
random fertilisation of gametes
What happens in the G phase of interphase
cell increases in size and new organelles are made in preparation for mitosis
what happens in telophase 2
chromosomes uncoil
spindle fibres break down
what is crossing over
occurs in prophase 1
exchanged when the chiasmata break
results in new combinations of alleles on the chromatids
what happens in prophase 1
chromosomes condense and become visible
homologous chromosomes attach to each other at chiasmata (non- sister chromosomes join together)
forming bivalents, spindle files form
what are the 4 stages of mitosis
prophase
metaphase
anaphase
telophase
what happens in anaphase
spindle files contract, pulling apart centromeres and pulling sister chromatids apart, going to opposite poles of the cell
what happens in metaphase
chromosomes line up at the equator of the cell, attached to the spindle fibres of the centromere, arranged as pairs of homologues chromosomes
what happens in anaphase 2
chromosomes seperate, and chromatids are pulled to the poles of the cell
spindle fibres contract, pulling the chromatids by the centromeres
what does cytokinesis occur
during telphase
what happens in anaphase 1
homologous pairs of chromosomes are pulled to poles of the cell,
spindle fibres contract, pulling the chromosomes by the centromere
summarise mitosis
2 daughter cells produced which are diploid and genetically identical over 1 nuclear division
what happens in metaphase 1
homologous pairs of chromosomes attach to spindle fibres at the equator of the cell
summarise meisois
4 daughter cells produced, which are haploid and genetically different, two nuclear divisors
Name the three phases of mitosis shown by C, D and E on the figure above.
Describe the role of the spindle fibres and the behaviour of the chromosomes during each of these phases.
C = prophase and
D = metaphase and
E = anaphase;
2. (In) prophase, chromosomes condense;
Accept chromatin for ‘chromosomes’ and for ‘condense’, shorten and thicken
3. (In) prophase OR metaphase, centromeres attach to spindle fibres;
4. (In) metaphase, chromosomes/pairs of chromatids at equator/centre of spindle/cell;
5. (In) anaphase, centromeres divide;
6. (In) anaphase, chromatids (from each pair) pulled to (opposite) poles/ends (of cell);
Accept for ‘chromatids’, chromosomes but reject homologous chromosomes
7. (In) prophase/metaphase/anaphase, spindle fibres shorten;
If mark point 1 is not credited = 4 max
Do not carry forward error from 1.
Accept letters for stages as indicated in 1.
Accept for ‘shorten’, contract
Describe the appearance and behaviour of chromosomes during mitosis.
(During prophase)
1. Chromosomes
coil / condense / shorten / thicken / become visible;
2. (Chromosomes) appear as (two sister) chromatids joined at the centromere;
(During metaphase)
3. Chromosomes line up on the equator / centre of the cell;
4. (Chromosomes) attached to spindle fibres;
5. By their centromere;
(During anaphase)
6. The centromere splits / divides;
7. (Sister) chromatids / chromosomes are pulled to opposite poles / ends of the cell / separate;
(During telophase)
8. Chromatids / chromosomes
uncoil / unwind / become longer / thinner.