Mitosis Flashcards

1
Q

DNA

A

Deoyribosenucleic Acid

Stores hereditary information within cells of all living organisms

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2
Q

DNA Structure

A

Double helix structure with hydrogenate bonds between complementary base pairs
Adenine - Thymine (A-T)
Cytosine - Uracil (C-G)

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3
Q

DNA Helicase

A

Breaks hydrogen bond between complementary base pairs

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4
Q

Topoisomerase

A

Unwinds supercoiled DNA and a single stranded binding protein prevents hydrogen bonds reforming

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5
Q

Primase

A

Binds a small length of RNA (a primer) to the DNA

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6
Q

DNA Polymerase

A

Travels down the DNA strand adding DNA nucleotides to the template strand

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7
Q

DNA Ligase

A

catalyses the condensation reaction to reform the sugar phosphate backbone between DNA nucleotides

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8
Q

Fidelity

A

The degree of exactness to which something is copied or reproduced

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9
Q

High dNTP levels

A

detrimental to the fidelity f replication as speed up repilcation

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10
Q

Low dNTP Levels

A

inhibit DNA replication allowing for mismatch repair to decrease the chance of mutation

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11
Q

Exonuclease

A

Travels in a 3’-5’ direction removing incorrect nucleotides

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12
Q

Direct Reversal

A

some DNA damaging reactions can be undone by enzymes in the cell

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13
Q

Excision Repair

A

the incorrect bases are removed and the damaged region is replaced

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14
Q

Telomerase

A

Allows cellular DNA to continues replication when there is an incomplete lagging strand

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15
Q

Mitosis

A

The production of genetically identical diploid cells for growth and repair.

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16
Q

G1 Phase

A

Metabolic changes prepare the cell for division and it passes the restriction point and the cell commits and moves to S Phase

17
Q

S Phase

A

DNA replication occurs and each chromosome is made up of two genetically identical sister chromatids

18
Q

G2 Phase

A

The cell assembles organelles and cytoplasmic material necessary for mitosis

19
Q

M Phase

A

Actual cell division- made up of Prophase, metaphase, Anaphase and Telophase

20
Q

Prophase

A

Chromosomes condense and appear visible, the nuclear envelope breaks down and the spindle fibres form

21
Q

Metaphase

A

Chromosomes line up along the equator of the cell and attach to the spindle fibres

22
Q

Anaphase

A

The spindle fibres contract and the centromeres divide, sister chromatids move to opposite poles of the cell

23
Q

Telophase

A

The nuclear envelope reforms and the chromatids de condense to form sister chromatids and cytokinesis occurs.