Mitosis

Question 1

Stage 1 of Mitosis

Answer 1

Prophase:

• Chromosomes condense and become visible
• Centrosomes move apart toward opposite poles
• Nucleoli begin to disappear

Question 2

Stage 2 of Mitosis

Answer 2

Prometaphase:

• Nuclear envelope breaks down
  *Microtubules from centrosomes invade the nucleus and connect to
  kinetochores in the centromere of each chromatid
• Sister chromatids attach to microtubules from opposite poles
• Mitotic spindle forms from three kinds of microtubules (astral,
  kinetochore, and polar)

Question 3

Stage 3 of Mitosis

Answer 3

Metaphase:

*Chromosomes align on the metphase plate w/sister chromatids facing opposite poles
*Forces pushing and pulling chromosomes to or from each
pole are in balanced equilibrium keeping chromosomes in
place

Question 4

Stage 4 of Mitosis

Answer 4

Anaphase:

• Centromeres of all chromosomes split simultaneously
• Kinetochore microtubules shorten and pull separated
  sister chromatids to opposite poles (characteristic V
  shape)

Question 5

Stage 5 of Mitosis

Answer 5

Telophase:

• Nuclear envelope forms around each group of chromatids
• Nucleoli re-form
• Spindle fibers disappear
• Chromosomes uncoil and reform as chromatin