Mitosis Flashcards
Mitosis
Process whereby one cell makes up 2 identical cells with same gentic makeup as original cell
Cytoplasmic cleavage
Furrow forms at eqautor of cell —deepens to divide cytoplasm in two —each new cell has its own nucleus
Interphase
Longest phase in cell cycle
Growth
DNA replication occurs just before prophase
Prophase
Chromatin network now forms visable chromasomes
Spindle fibres form
Nuclear membrane disappears
Nucleolus disappears
Metaphase
Chromosomes form at equator of cell
Chromosomes attach to spindle fibres at centromere
Centrioles are on opposite poles
Anaphase
Centromere holding identical chromatids split
Spindle fibres pull the daughter chromosomes to opposite poles
Telophase
Identical chromosomes reach the poles to now form chromatin network
Nuclear membrane forms around chromatin material
Importance of mitosis
New cells formed for growth
Replacement and repair of damaged cells
New cell formed is identical to original cell
Simple unicelluar organisms to reproduce asexually
Cancer
Cell division by mitosis becomes uncontrolled
Tumour forms
Benign tumour
Cells trapped in a capsule
Malignant tumour
Cells have moved to other parts of the body
Carcinogens
Substances which cause cancer
Smoking —alcohol—asbestos—chromate—nickel
Chemotherapy
Chemicals injected via IV
Chemicals kill cancerous cells
Non-cancerous cells are destroyed aswell—hair loss + nausea
Radiation
X-rays zap the tumour —this kills cancerous cells
Side effects — tiredness + loss of appetite
Surgery
Involes removing cancerous cells