mitosis Flashcards

1
Q

what is mitosis?

A

formation of two identical daughter cell by the division of one parent cells. daughter cell has the same number of chromosomes as the parent cell

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2
Q

who discover mitosis in plants and animals?

A

plants: Stasburger

animals :Walter Flemming

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3
Q

occurrences of mitosis?

A

stomatic / body cells - animal

merismatic cell - plants

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4
Q

mechanisms of mitosis?

A

1) karyokinesis

2) cytokinesis

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5
Q

what are the four phases under karyokinesis?

A

1) prophase
2) metaphase
3) anaphase
4) telophase

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6
Q

explain prophase.

A

1) chromatin condenses to form two coiled sister chromatids. chromatids are joined by the centromere, their end is not clearly visible at this stage this stage is called spireme stage
2) centrosomes move towards the poles radiate microtubules called aster. aster along with spindle fibres for mitotic apparatus
3) at end of prophase ER, nucleolus, the Golgi body and nuclear membrane dissolves

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7
Q

explain metaphase.

A

1) nuclear envelop dissolves
2) equatorial / metaphasic plate forms at the centre
3) chromatids are thickest and shortest at this stage is easy to study their morphology
- mitotic spindle formation is complete

4) chromosomes are brought towards the metaphasic plate - congression
5) chromosomes align themselves on the metaphasic plate
6) chromosomal fibres attach to the kinetochores

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8
Q

what is kinetochore?

A

the disc-shaped structure around the centromere.

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9
Q

what is the chromosome to chromosomal fibre ratio?

A

1:2

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10
Q

explain Anaphase.

A

1) spindle fibres shortens, centrosomere splits and the chromosomes of the future daughter cell migrates toward the poles.
2) formation of inter-zonal fibres occur
3) this is the best stage to study the shape of chromosome - V, L, J, I

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11
Q

what are inter zonal fibres?

A

Fibres that are present between centromeres of separating.

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12
Q

explain Telophase.

A

1) sister chromatids reach the poles
2) decondensation of chromatids(uncoiling)
3) spindle fibres disappears
4) ER, nucleolus, nuclear membrane, Golgi body reappears.
5) nuclear envelope develops and covers the chromatin cluster at the poles forming two daughter nuclei.

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13
Q

how does cytokinesis occur in animals?

A

1) cleavage furrow
2) centric
3) Amphiastral
4) cytokinesis occur from outside to inside - centripetal

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14
Q

how does cytokinesis occur in plants?

A

1) formation of the cell plate in the middle of the cell
2) Acentric
3) Astral
4) cytokinesis occur from inside to outside - Centrifugal

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15
Q

how is a cell plate formed?

A

the phragmoplast is formed by the Golgi body which centrifugally forms the cell plate

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16
Q

what the significances of mitosis?

A

1) maintenance of chromosomal number - genetic stability
2) healing and regeneration
3) repair
4) maintenance of shape
5) growth
6) reproduction

17
Q

what is the formulae for the no. of mitotic divisions for “n” no. of cells?

A

n-1

18
Q

what is the formulae for the no. of generations(n) required for “Y” no. of cells?

A
Y=2^n 
eg: for 4 cells
--> 2^n = 4
    therefore n = 2
thus no. of generations required to form 4 cells is 2
19
Q

why is mitosis called equational division?

A

maintains equal no. of chromosomes.

20
Q

when is the increase in the number of chromosomes first observed?

A

anaphase