introduction Flashcards
what is cells cycle?
the sequence of events which includes the duplication of the genome, synthesis of its constituents and finally division into two daughter cells.
how long does the cell cycle last (period)?
it depends on the organism.
eg: yeast - 90min, human cell - 24hrs
what are the two phases under in cell cycle?
1) interphase / resting phase:
- replication of DNA
- synthesis of organelles
- takes more than 95% of the cell cycle
2) mitotic phase/division phase :
- cell divides
- less than 5% of the cell cycle
what are the three phases under interphase?
1) G1 phase
2) S phase
3) G2 phase
4) G0 phase(extended)
what do G and S stand for?
G - growth/gap
S - synthesis
explain the G1 phase?
- it is a post-mitotic phase
- cell duplicates most of the cell organelles
- cell synthesises :
1) protein , @) ATP, 3) amino acid , 4) nucleotides 5) RNA etc. - this phase is shorter in cells that frequently divide
- this phase is longer in cells that divide less frequent;y
what is a major checkpoint?
- present betweenG1 and S phase
- produces G1 cyclic and CDC 2 kinase protein
explain the S phase?
- on chromatid chromosome duplicates to form two chromatid chromosome with 2 sister chromatids
- no. chromosomes remain the same
- amount of genetic material increases
- synthesis of histone proteins
- centriole duplication occures
explain the G2 phase?
- pre mitotic phase
- synthesis of mitochondria, chloroplast and Golgi body
- tubuin protein syntheis
- RNA synthesis
what is the minor checkpoint?
_ present between mitotic and G 2 phase
- mitotic cyclin and CDC2 kinase protein
explain the G0 phase?
cell enters a quiescent stage and are metabolically active at this phase but they do not proliferate unless brain and heart cells are asked to do so.