introduction Flashcards

1
Q

what is cells cycle?

A

the sequence of events which includes the duplication of the genome, synthesis of its constituents and finally division into two daughter cells.

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2
Q

how long does the cell cycle last (period)?

A

it depends on the organism.

eg: yeast - 90min, human cell - 24hrs

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3
Q

what are the two phases under in cell cycle?

A

1) interphase / resting phase:
- replication of DNA
- synthesis of organelles
- takes more than 95% of the cell cycle
2) mitotic phase/division phase :
- cell divides
- less than 5% of the cell cycle

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4
Q

what are the three phases under interphase?

A

1) G1 phase
2) S phase
3) G2 phase
4) G0 phase(extended)

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5
Q

what do G and S stand for?

A

G - growth/gap

S - synthesis

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6
Q

explain the G1 phase?

A
  • it is a post-mitotic phase
  • cell duplicates most of the cell organelles
  • cell synthesises :
    1) protein , @) ATP, 3) amino acid , 4) nucleotides 5) RNA etc.
  • this phase is shorter in cells that frequently divide
  • this phase is longer in cells that divide less frequent;y
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7
Q

what is a major checkpoint?

A
  • present betweenG1 and S phase

- produces G1 cyclic and CDC 2 kinase protein

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8
Q

explain the S phase?

A
  • on chromatid chromosome duplicates to form two chromatid chromosome with 2 sister chromatids
  • no. chromosomes remain the same
  • amount of genetic material increases
  • synthesis of histone proteins
  • centriole duplication occures
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9
Q

explain the G2 phase?

A
  • pre mitotic phase
  • synthesis of mitochondria, chloroplast and Golgi body
  • tubuin protein syntheis
  • RNA synthesis
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10
Q

what is the minor checkpoint?

A

_ present between mitotic and G 2 phase

- mitotic cyclin and CDC2 kinase protein

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11
Q

explain the G0 phase?

A

cell enters a quiescent stage and are metabolically active at this phase but they do not proliferate unless brain and heart cells are asked to do so.

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