Mitochondrial Genetics Flashcards
1
Q
What is the main purpose of mitochondria?
A
Oxidative phosphorylation
Where ATP is produced as result of transfer of electrons from NADH or FADH2 to O2 by a series of electron carriers
2
Q
What is homoplasy?
A
Where all copies are identical
3
Q
What is heteroplasy?
A
Where more than one type is present
4
Q
What do nuclear derived proteins do?
A
Controls transcription and processing of mitochondrial genomes as well as being involved in translation
5
Q
Features of mitochondrial disorders?
A
Respiratory chain respiratory
Reductions in O2 consumption and Atp synthesis
Increased lactic acid
Influence tissues with higher energy demand
