Complex Diseases Flashcards
1
Q
What are complex disease?
A
Disease that have multiple genes that contribute to disease and the environment can effect it
2
Q
What are Mendelian traits?
A
Where one factor or gene is involved and knowledge of that genotype is highly predictive
3
Q
What are polygenic disorders?
A
Where many genetic variants contribute
4
Q
What is GWAS?
A
Genome wide association study is where 1 million single nucleotide polymorphism across the genome are used to identify genes for polygenic disorders
5
Q
What is penetrative?
A
Probability of developing the disease
6
Q
What does odds ratio do?
A
It compares disease risk for different genotypes
