Epigenetics

Question 1

What do epigenetic factors do?

Answer 1

Regulate gene expression and alter these factors

Question 2

What are some epigenetic factors?

Answer 2

DNA methylation
Justine modifications
Non-coding RNA variants

Question 3

What is DNA methylation?

Answer 3

Where a methyl group is added to cytosine

Question 4

What are the 4 most common Justine modifications?

Answer 4

Acetylation, methylation, phosphorylation and ubiquitylation

Question 5

What are readers, writers and erasers?

Answer 5

Writers - introduce various chemical modifications on DNA and his tones
Readers - specialised domain containing proteins that identify and interpret those modifications
Erasers - dedicated group of enzymes that remove chemical tags

Question 6

What are imprinted cells?

Answer 6

Where either the maternal or paternal allele is expressed, not both

Question 7

What are some DNA modifiers?

Answer 7

Hydroxymethylation, methylation and formulation

Question 8

What are some Histone modifiers?

Answer 8

Acetylation, methylation, phosphorylation, chromatin conformation, histone chaperone