Miscellaneous Pain medications

Question 1

MOA of Tramadol

Answer 1

binds to µ receptors

and it also weakly inhibits norepinephrine and serotonin reuptake,
which is believed to augment pain signal transmission inhibition

Question 2

MOA of Methadone

Answer 2

= µ agonist opioid
& = N-methyl-D-aspartate (NMDA) antagonist

produces pain relief

Question 3

MOA of Ketamine ?

Answer 3

= NMDA antagonist that can also be used to provide analgesia

Question 4

Psychotomimetic adverse effects of Ketamine ?

Answer 4

hallucinations

and nightmare

Question 5

What type of pain are Anticonvulsants used to treat ?

Answer 5

To treat
persistent neuropathic pain,

especially pain of a stabbing, shooting, or electric-like quality.

Question 6

Name 2 Anticonvulsants

Answer 6

gabapentin and pregabalin

Question 7

MOA of Anticonvulsants

Answer 7

Anticonvulsants act by stabilizing nerve membranes,
reducing excitability,
& reducing spontaneous neuronal firing