Adjuvant Analgesics Treatments

Question 1

Name 2 Local anaesthetics

Answer 1

lignocaine and bupivacaine.

Question 2

MOA of Local anaesthetics ?

Answer 2

 Block sodium ion channels to prevent the conduction of nerve impulses

Question 3

Formulations of Local anaesthetics ?

Answer 3

also available as creams and gels for topical application.

Question 4

Local anaesthetics admin routes ?

Answer 4

can also be infused near the spinal cord (intrathecal, epidural) or into surgical incision sites.

Question 5

What are the dose related adverse effects of local anaesthetics ?

Answer 5

dizziness, confusion, metallic taste,

& seizures = are signs of neurotoxicity.

Question 6

What are the Potential cardiovascular reactions of Local anaesthetics ?

Answer 6

dysrhythmias; hypotension;

if severe
= cardiovascular collapse

Question 7

Name allergic reactions to local anaesthetics ?

Answer 7

rash, urticaria,

or difficulty breathing.

Question 8

Name 3 Muscle relaxants

Answer 8

benzodiazepines, antihistamines, and sedatives.

Question 9

Which muscle relaxant is used for pain associated with Muscle Spasm ?

Answer 9

benzodiazepines

are used only for pain associated with muscle spasm.

Question 10

Admin route of benzodiazepines ?

Answer 10

orally,
parenterally,
rectally in suppository form

Question 11

Problem with concurrent muscle relaxants

& opioid medications.

Answer 11

Increases risk of respiratory depression

Question 12

Problem with concurrent muscle relaxants

& opioid medications.

Answer 12

Increases risk of respiratory depression