Miscellaneous Notes/Research Flashcards
What is the usual duration between acute COVID infection and onset of MIS-C?
two to six weeks
What CBC findings are seen in MIS-C?
lymphocytopenia
neutrophilia
mild anemia
thrombocytopenia
Which inflammatory markers are commonly elevated with MIS-C?
CRP, ESR
D-Dimer, fibrinogen
Ferritin
Procal
Interleukin
Do inflammatory markers correlate with severity of illness?
yes
Which 3 organs are important to evaluate in MIS-C
heart
liver
kidneys
Which inflammatory marker is NOT useful to trend in MIS-C?
ESR, because tx of MIS-C is commonly IVIG which elevated ESR
What is the most common cause of aortic stenosis?
degenerative calcification; associated with aging, HTN, HLD, tobacco use, DM
Which 3 electrolyte disturbances increase the risk for torsades de pointes?
Hypokalemia, hypomagnesemia, hypocalcemia
What is first, second, and third line treatments for Torsades?
- magnesium and defibrillation
- magnesium and defibrillation
- Isoproterenol with overdrive pacing by temporary transvenous pacemaker
What CD4 counts are associated with toxoplasmosis?
CD4 <100
What is the first line treatment for toxoplasmosis?
pyrimethamine
sulfadiazine
+leucovorin – co-administer to prevent pyrimethamine-induced hematologic toxicity
What is the first/initial treatment for hyponatremia caused by SIADH?
fluid restriction
What is the best next step when a CT scan is concerning for NPH?
Brain MRI
What is the confirmatory test for NPH after MRI?
high volume lumbar puncture with monitoring for improvement of symptoms–specifically gait improvement; opening pressure and CSF studies should be normal
What is the treatment for NPH?
ventricular shunting
What is Spodick sign on ECG?
downward sloping TP segment seen in lead II and precordial leads; specific but not sensitive sign for acute pericarditis
What is first line therapy for acute pericarditis?
NSAID – ie Ibuprofen
Infarction of which coronary artery territory can lead to atrioventricular block?
Inferior myocardial infarction (the right coronary artery supplies the atrioventricular node and inferior heart).
What is the treatment of sulfonylurea overdose?
Dextrose
Octreotide
What is the dose of Octreotide for adults in sulfonylurea overdose?
Adults:
50-150 mcg q6h
What is the dose of Octreotide for children in sulfonylurea overdose?
1-1.5 mcg/kg (up to 150 mcg) q6h
What is the formula for estimating weight for pediatric dextrose administration?
(2 x age in years) + 8
What is the dose and dextrose concentration for pediatric hypoglycemia in ages <1 year old?
5-10 mL/kg of D10
What is the dose and dextrose concentration for pediatric hypoglycemia in ages 1-8 years old?
2-4 mL/kg of D25
What is the dose and dextrose concentration for pediatric hypoglycemia in ages >8 years old?
1-2 mL/kg of D50
Is serum insulin concentration high or low with sulfonylurea ingestion?
High
What are the 3 treatments for HACE?
supplemental O2
descent
steroids (dexamethasone)
What is the rule of 9s for burn estimation?
9% Face
9% - chest
9% - abdomen
9% upper back
9% - lower back
9% RUE
9% LUE
9% LLE FRONT
9% RLE FRONT
What blood pressure is required prior to Alteplase administration?
SBP <185
DBP <110
What BP should be maintained for the first 24 hours after alteplase administration?
<180/105
Within what amount of time should alteplase be administered from last known normal?
4.5 hours
In addition to careful cleaning, tdap, and pain management, what is a treatment for stingray injury?
immersion in hot water (45C or 113F) for 30-90 minutes or until pain subsides – believed to break down the poison
What organism causes tinea versicolor?
Malassezia furfur
What is the treatment for tinea versicolor/malassezia furfur infection?
topical selenium sulfide
What is the role of desmopressin in the treatment of hyponatremia?
helps prevent a continued rapid rise in sodium
What are the four Kanavel Criteria for Flexor Tenosynovitis?
- Tenderness along the course of the flexor tendon
- Fusiform or symmetrical swelling of the finger
- Pain with passive extension
- Flexed posture of the finger
What factors are included in the Opioid Risk Assessment Tool?
- Family History of substance use (EtOH, illegal drugs, prescription drugs)
- Personal history of substance use (EtOH, illegal drugs, prescription drugs)
- Age 16-45
- History of preadolescent sexual abuse
- History of psych disease – ADHD, OCD, Bipolar, schizophrenia, depression