Miscellaneous Notes/Research Flashcards
What is the usual duration between acute COVID infection and onset of MIS-C?
two to six weeks
What CBC findings are seen in MIS-C?
lymphocytopenia
neutrophilia
mild anemia
thrombocytopenia
Which inflammatory markers are commonly elevated with MIS-C?
CRP, ESR
D-Dimer, fibrinogen
Ferritin
Procal
Interleukin
Do inflammatory markers correlate with severity of illness?
yes
Which 3 organs are important to evaluate in MIS-C
heart
liver
kidneys
Which inflammatory marker is NOT useful to trend in MIS-C?
ESR, because tx of MIS-C is commonly IVIG which elevated ESR
What is the most common cause of aortic stenosis?
degenerative calcification; associated with aging, HTN, HLD, tobacco use, DM
Which 3 electrolyte disturbances increase the risk for torsades de pointes?
Hypokalemia, hypomagnesemia, hypocalcemia
What is first, second, and third line treatments for Torsades?
- magnesium and defibrillation
- magnesium and defibrillation
- Isoproterenol with overdrive pacing by temporary transvenous pacemaker
What CD4 counts are associated with toxoplasmosis?
CD4 <100
What is the first line treatment for toxoplasmosis?
pyrimethamine
sulfadiazine
+leucovorin – co-administer to prevent pyrimethamine-induced hematologic toxicity
What is the first/initial treatment for hyponatremia caused by SIADH?
fluid restriction
What is the best next step when a CT scan is concerning for NPH?
Brain MRI
What is the confirmatory test for NPH after MRI?
high volume lumbar puncture with monitoring for improvement of symptoms–specifically gait improvement; opening pressure and CSF studies should be normal
What is the treatment for NPH?
ventricular shunting