Miscellaneous Flashcards
Beauchamp & Childress’ Principles
Autonomy (free will)
Beneficence (good for others)
Non-Maleficence (do no harm)
Justice (fair distribution of benefits/risks/costs)
What is a conceptus
Fertilisation to 3 weeks
What is a Embryo
4 to 8 weeks
What is a foetus
Week 9 to birth
Gameotogenesis?
Formation of Germ cells
Fertilisation?
Formation of Zygote
Cleavage?
Rapid cell division
Gastrulation?
Formation of germ layers
Morphogenetic
Folding of embryo
Ectoderm
Produces skin and nervous system
Mesoderm
Produces organs
Endoderm
Produces lining of gut & lung bud
Cell cycle?
G0 - Cells resting G1 - cells ready to replicate S phase - Replication G2 - growth M phase - Mitosis
Variation caused by:
Crossing over
Segregation of homologous chromosomes
Meiosis
1 diploid to 4 haploids
Metacentric chromosome
Both arms same length
Chromosome is Acrocentic
P arm difficult to see
Chromosome is telocentric
Centromere at terminal end
Aneuploudy
Monosomy - chromosome missing
Trisomy - additional chromosome
Monosomy of sex chromosomes
Turners syndrome
Trisomy of chromosome 21
Down’s
FISH?
Prove that applies fluorescent stain making chromosome visible
Autosomal dominant
1 faulty copy required, 50% chance of inheritance
Autosomal recessive
2 faulty copies required, 25% chance of inheritance
Mitochondrial
Disease passed from mother
Oncogenes
Promote cell division
Tumour suppression genes
Inhibit cell division
Gram +ve stain:
Purple (due to thick peptidoglycan layer)
Gram -be stain:
Pink (due to thin peptidoglycan layer)
Exotoxins
Produced by gram +ve
Endotoxins
Produced by gram -ve
Streptococci
Gram +ve chains
Staphylococci
Gram +ve clusters
Classifying different streptococci
Haemolytic test
Alpha (partial) - strep. Pneumoniae, viridans
Beta (full) - Group A and B
Gamma (none) - enterococcus
Left shift oxyhaemoglobin curve
Reduced 2,3 DPG, Hypo…., alkalosis, CO poisoning
Right shift oxyhaemoglobin curve
Hyper…. acidosis, sickle cell didease