Miscellaneous Flashcards
1
Q
ETC Inhibitors (4)
A
- Rotenone- Complex I
- Cntimycin A- Complex III
- Cyanide- Complex IV
- Carbon Monoxide- Complex IV
Decreased protein gradient
2
Q
ATP Synthase Inhibitor
A
Oligomycin
Increased protein gradient
3
Q
Uncoupling Agents (MoA and names)
A
MoA: Increase permeability of membrane, decreased proton gradient and increased O2 consumption. Produces heat
- 2,4-Dinitrophenol (weight loss drug)
- Aspirin
- Thermogenin in brown fat