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Gastrointestional > miscellaneous > Flashcards

miscellaneous Flashcards

1
Q

what are the main neurotransmitters involved in nausea

A

dopamine , 5HT and Ach

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2
Q

examples of anti-histamines tha are anti-emetics
indications and SE

A

cyclizine
promethazine

motion sickness
SE - sedation

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3
Q

examples of anti-muscarinics that are anti emetic
indications and SE

A

Scopolamine AKA hyoscine or devils breath

motion sickness and post op
SE - dry mouth

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4
Q

serotonin antagonists that are anti emetic
indications and SE

A

ondansetron
granisetron
palonosetron

post chemo or post op
SE - constipation, diarrhoea, headache

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5
Q

dopamine antagonists that are anti emetic

indications and SE

A

chlopromazine
domperidone
prochloperazine
metoclopramide

general nausea
SE - diarrhoea and EPSE

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6
Q

example of bulk forming laxative and mechanism of action

A

ispagula bulk
relieves constipation by increasing faecal mass and stimulation peristaltic refelx

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7
Q

example of osmotic laxative and drug action

A

lactulose- pulls water into lumen to soften faecal matter

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8
Q

example of a stimulant laxative and drug action

A

senna - irritate sensory nerve endings stimulating colonic motility and reducing water absorption

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Gastrointestional (6 decks)

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