Misc Skin Disorders Flashcards
Types of psoriasis
Plaque: most common, slow onset, well defined symmetrical lesions. Salmon pink papules and plaques with silver scales
Inverse: sharply demarkated plaques WITHOUT scales. In groin, axilla under breasts etc
Guttate: sudden onset, in younger population. Scattered teardrop shaped lesions
Erythrodermic: scaling whole body. Shedding skin so painful and pruritic. at risk for infection and electrolyte imbalance (need to be inpatient)
Pustular: generalized and life threatening. Abrupt onset of little pustules (not scales)
Nails: likely to have psoriatic arthritis
Auspitz sign
Removal of scales results in small blood droplets
Koebner’s phenomenon
Plaques at sites of former skin injury (ex. bug bite, bruises and scrapes, burn, etc)
Some drugs that may exacerbate include
Beta-blockers, NSAIDs, lithium, ACEI, digoxin
Plaque Psoriasis Treatment
Topical therapy - Emollients (Lubriderm, Eucerin)
Steroids Can be continued as long as pt has thick active lesions. Back off on frequency and strength once under better control
Vitamin D Analog: Calcipotriol (Dovonex)
Vitamin A Derivatives (Retinoids): Tazarotene (Tazorac)
Calcineurin inhibitors: Tacrolimus (Protopic), Pimecrolimus (Elidel)
Coal Tar preparations
Pemphigus
Intraepidermal blistering secondary to an autoimmune process
Mortality rate as high as 5%
Flaccid bullae that often begin in the oropharynx and then may spread to involve the scalp, face, chest, axillae and groin
Nikolsky sign
Dx with skin biopsy
Bullous Pemphigoid
Chronic, subepidermal blistering autoimmune disease
May possibly be triggered by a drug reaction or infection
Almost exclusively in the elderly population (>60)
Blisters are tense and fluid filled
Lipoma
Benign subcutaneous tumors
Soft, rounded, and movable against the overlying skin!
Composed of fat cells that have the same morphology as normal fat cells
