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Dispensing Final 2013 > Misc Section Final > Flashcards

Misc Section Final Flashcards

1
Q

Acne agents 2 Trades?

A

Differin

Duac

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2
Q

Differin generic and details?

A

adapalene (acne agent)
• qday
• Cream, lotion, gel
• Reduces comedo formation; acne may worsen the first few weeks due to exacerbation of deep, unseen lesions

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3
Q

Duac generic and details?

A

benzoyl peroxide, clindamycin (acne agent)
• qday
• Gel
• Refrigerate in the pharmacy; can be stored at room temperature for 60 days

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4
Q

Anticoagulant indications and definitions?

A

Indicated for thrombosis; do not dissolve thrombi just keep them from getting bigger
• Thrombosis – presence of a thrombus
• Thrombus – clot

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5
Q

Anticoagulant Trades?

A

Coumadin
Pradaxa
(Mephyton)

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6
Q

Coumadin generic, strengths, MOA

A

warfarin (anticoagulant)
• qday
• 1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 mg tablet
• Inhibits the synthesis of the Vitamin K dependent clotting factors II, VII, IX, and X
• Do not change diet; increasing Vitamin K intake could decrease Coumadin effectiveness

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7
Q

warfarin monitoring details?

A
  • International Normalized Ratio is used to monitor warfarin therapy
  • Patient not taking warfarin → INR of 1 is normal
  • Patient taking warfarin → INR of 2-3 is normal: more than 3 → decrease dose; less than 2 → increase dose
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8
Q

Trade and generic for warfarin overdose?

A

Mephyton - phytonadione

Vitamin K tablets for Coumadin overdose

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9
Q

Pradaxa generic, dosing, MOA

A

dabigatran
• BID
• Thrombin inhibitor; thrombin is an enzyme used for fibrin formation and fibrin is necessary for clot formation
• Does not require monitoring

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10
Q

HMG-CoA Reductase Inhibitor MOA, counseling, dosing

A

Inhibit enzyme preventing the conversion of HMG-CoA to mevalonate (decrease cholesterol)
o May cause rhabdomyolysis – muscle pain and weakness
• Muscle tissue is destroyed → myoglobin is released → may precipitate in the kidney → renal failure
o Administer in the evening because cholesterol is synthesized mainly at night
o All qday (Exception: Lescol BID)

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11
Q

HMG-CoA Reductase Inhibitor generics?

A 
fluvastatin
pravastatin
simvastatin
atorvastatin
rosuvastatin
pitavastatin
lovastatin
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12
Q

fluvastatin Trade?

A

Lescol, Lescol XL

HMG-CoA Reductase Inhibitor

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13
Q

pravastatin Trade?

A

Pravachol

HMG-CoA Reductase Inhibitor

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14
Q

simvastatin Trade?

A

Zocor

HMG-CoA Reductase Inhibitor

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15
Q

atorvastatin Trade?

A

Lipitor

HMG-CoA Reductase Inhibitor

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16
Q

rosuvastatin Trade?

A

Crestor

HMG-CoA Reductase Inhibitor

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17
Q

pitavastatin Trade?

A

Livalo

HMG-CoA Reductase Inhibitor

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18
Q

lovastatin Trade?

A

Mevacor and Altoprev

HMG-CoA Reductase Inhibitor

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19
Q

Bile Acid Sequestrants dose form and counseling?

A

o Powder for oral suspension → mix with 8 ounces water and drink
o HMG-CoA reductase inhibitors and bile acid sequstrants should not be administered concurrently → reduced bioavailability of HMG-CoA reductase inhibitors

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20
Q

Bile Acid Sequestrants generics?

A

cholestyramine
colestipol
colesevelam

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21
Q

cholestyramine Trade?

A

Questran, Prevalite

Bile Acid Sequestrants

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22
Q

colestipol Trade?

A

Colestid

Bile Acid Sequestrants

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23
Q

colesevelam Trade and details?

A 
Welchol (Bile Acid Sequestrant)
•625 mg tablet: 6 tablets qdaily or 3 tablets BID
•1.875 g packet for oral suspension: BID
•3.75 g packet for oral suspension: qday
•3.75 g daily dose
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24
Q

Miscellaneous Cholesterol drug generics? (5)

A

ezetimibe, exetimibe + simvastatin,
omega 3-fatty acids, gemfibrozil
fenofibrate, fenofibric acid

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25
Q

ezetimibe Trade and MOA?

A

Zetia

inhibits cholesterol absorption in the small intestine

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26
Q

ezetimibe combination product?

A

Vytorin

ezetimibe, simvastatin

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27
Q

omega 3-fatty acids Trade and dosing?

A

Lovaza
•1000 mg capsule
•4 grams qday; single dose or 2 capsules BID

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28
Q

fenofibrate Trade?

A

Tricor, Triglide, Lofibra

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29
Q

fenofibric acid Trade and extra?

A

Trilipix

•May be used concomitantly with an HMG-CoA reductase inhibitor

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30
Q

gemfibrozil Trade and dosing?

A

Lopid

BID

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31
Q

Antimigraine agents generics?

Super Elephants Feel nauseated zooming along rollercoasters)

A 
sumatriptan
eletriptan
frovatriptan
naratriptan
zolmitriptan
almotriptan
rizatriptan
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32
Q

sumatriptan Trade and dosing?

A

Imitrex
• Tablets: 25 mg, 50 mg, 100 mg → max daily dose of 200 mg
• Injection: 4 mg/0.5 mL, 6 mg/0.5 mL
• Nasal spray: 20 mg

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33
Q

eletriptan Trade and dosing?

A

Relpax

•20 mg & 40 mg tablet→ max daily dose of 80 mg

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34
Q

frovatriptan, naratriptan Trades?

A

Frova - frovatriptan

Amerge - naratriptan

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35
Q

zolmitriptan, almotriptan Trades?

A

Zomig - zolmitriptan

Axert - almotriptan

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36
Q

rizatriptan Trade and dosing?

A 
Maxalt (5mg, 10mg tablet → max daily dose of 30 mg)
Maxalt MLT (5mg, 10mg OTD)
37
Q

Daily vit D and calcium needs for age groups?

A
  • Patients under 70 need 600 units/day of vitamin D
  • Patients over 70 need 800 units/day of vitamin D
  • Women under 50 and men under 70 need 1,000 mg/day of calcium
  • Women over 50 and men over 70 need 1,200 mg/day of calcium
38
Q

Osteoporosis medication counsing?

A

o Take on an empty stomach, take with a full glass of water, and remain upright for 30 minutes
• Can cause esophageal irritation

39
Q

Osteoporosis generics?

A

risedronate, ibandronate, alendronate
alendronate/cholecalciferol
calcitonin-salmon
teriparatide

40
Q

risedronate Trade and dosing?

A

Actonel (bisphosphonate)
• qweekly – 35 mg tablet
• qmonthly – 70 mg tablet

41
Q

ibandronate Trade and dosing?

A

Boniva (bisphosphonate)
• qmonthly
• 150 mg tablet

42
Q

alendronate Trade and dosing?

A

Fosamax (bisphosphonate)
• Qweekly
• 70 mg tablet

43
Q

alendronate combination product Trade and dosing?

A

Fosamax Plus D (cholecalciferol)
• Qweekly
• Tablet
• 4 tablets/pack
• 70 mg alendronate, 70 mcg cholecalciferol (2,800 units of Vitamin D)
• 70 mg alendronate, 140 mcg cholecalciferol ( 5,600 units of Vitamin D)

44
Q

calcitonin-salmon Trade and dosing, storage?

A

Miacalcin, Fortical
• One spray qday, Nasal spray
• Refrigerate in the pharmacy; can be stored at room temperature for 30 days
• Cannot be substituted for one another

45
Q

teriparatide Trade and dosing?

A

Forteo
•qday SQ injection
•Stimulates osteoblast production and bone formation
•Refrigerate

46
Q

Proton Pump Inhibitor indications, MOA?

A

o Indicated for treatment of duodenal ulcers, GERD, gastric ulcers, and Zollinger-Ellison syndrome
o Block the final step of gastric acid production by inhibiting the proton pump in the gastric mucosa
o Acid-labile medications
o Administered qday

47
Q

PPI generics?

L_, O_, PRO

A 
lansoprazole
dexlansoprazole
omeprazole
esomeprazole
pantoprazole
rabeprazole
omeprazole, sodium bicarbonate
48
Q

lansoprazole Trade and dosing?

A

Prevacid - 15mg, 30mg Delayed release capsule; 15mg is OTC

Prevacid Solutab - 15mg, 30mg ODT (enteric coated microgranules)

49
Q

dexlansoprazole Trade and dosing?

A

Dexilant - R-isomer

dual release mechanism: initial release, 2nd release 4 hours later

50
Q

omeprazole Trade and dosing?

esomeprazole Trade?

A

Prilosec (omeprazole)
• 10, 20, 40 mg delayed release capsule
• 20 mg delayed release tablet
Nexium (esomeprazole)

51
Q

pantoprazole, rabeprazole Trades?

A

Protonix (pantoprazole)

Aciphex (rabeprazole)

52
Q

omeprazole combination product Trade and details?

A

Zegerid, Zegerid OTC
omeprazole, sodium bicarbonate
• Capsule
• Single packets of powder for oral suspension → mix with 30 mL of water before using
• Sodium bicarbonate protects omeprazole from gastric acid

53
Q

Histamine-2 receptor antagonist MOA and Indications?

A

o Inhibit gastric acid secretion by inhibiting the action of histamine at the H-2 receptors on the parietal cells
o Indicated for duodenal ulcers, gastric ulcers, heartburn, and GERD

54
Q

H-2 receptor antagonist generic/Trade and dosing?

A

Zantac - ranitidine
• 75, 150, 300 mg tablet: 75 and 150 mg are available OTC
• 15 mg/mL syrup

55
Q

Indication and generics for antihcolinergic?

A

Ind: overactive bladder
trospium
darfenacin
solifenacin

56
Q

trospium Trade and form?

A

Sanctura - IR tab
Sanctura XR - ER capsule
anticholinergic

57
Q

darifenacin, solifenacin Trade and dosing?

A

Enablex darifenacin qday

Vesicare solifenacin qday

58
Q

Phosphodiesterase Inhibitors generics?

A

sildenafil - Viagra
vardenafil - Levitra
tadalafil - Cialis

59
Q

sildenafil Trade and strengths, counseling

A

Viagra
• 25 mg, 50 mg, 100 mg tablet
• Take on empty stomach one hour before sexual activity
• Seek medical assistance if priapism lasts more than 4 hours
• No effect if there is no sexual stimulation

60
Q

vardenafil Trade and strength, counseling?

A

Levitra
• qday
• 2.5 mg, 5 mg, 10 mg, 20 mg tablet
• Take on empty stomach

61
Q

tadalafil Trade and strength, indications

A 
Cialis
•	qday
•	2.5 mg, 5 mg, 10 mg, 20 mg tablet
•	Treatment of BPH symptoms and impotence
•	Can be taken without regard to meals
62
Q

Alzheimer’s drug category, MOA?

A

o Cholinesterase inhibitors: inhibit cholinesterase → increase ACh levels in the brain
o NMDA receptor antagonist: block actions of glutamate by binding to NMDA receptors

63
Q

cholinesterase inhibitor generics?

A

rivastigmine - Exelon Patch
donepezil - Aricept
galantamine - Razadyne
memantine - Namenda (XR)

64
Q

rivastigmine, galantamine Trades?

A

Exelon Patch - rivastigmine

Razadyne - galantamine

65
Q

donepezil Trade and strengths?

A 
Aricept
•	qday
•	5 mg, 10 mg, 23 mg tablet
•	5 mg and 10 mg ODT
•	Patients can increase dose to 23 mg if taking 10 mg for three months
66
Q

memantine Trade and strengths?

A 
Nemenda - BID
5mg, 10mg tab; oral solution
Namenda XR - QDay
, 14, 21, and 28 mg ER capsule
•	Initial dose: 7 mg qday → increase in weekly 7 mg increments
•	Maintenance dose: 28 mg qday
67
Q

5 alpha reductase inhibitors MOA and trades?

A

Metabolizes testosterone to dihydrotestosterone → alopecia and prostate enlargement
finasteride
dutasteride

68
Q

finasteride Trades and dosing?

A

Proscar (5mg qday for prostate reduction)
Propecia (1mg qday for alopecia)
must use for 3 months to see results and withdrawal of treatment leads to reversal of effect within 12 months

69
Q

dutasteride Trade and indication?

A

Avodart

Benign prostatic hyperplasia

70
Q

Skeletal Muscle Relaxants (4)

sick zebras feel sad

A

Skelaxin metaxolone
Zanaflex tizanidine
Flexeril cyclobenzaprine
Soma carisoprodol

71
Q

Bowel disease suppressant indication and generic?

A

mesalamine

for ulcerative colitis

72
Q

Trades for mesalamine and dosing?

6

A 
Delzicol - TID 400mg DR cap
Asacol HD - TID 800mg DR tab
Lialda - QDay 1.2g tab
Pentasa - ER capsule
Rowasa - rectal suspension
Canasa - rectal suppository
73
Q

topical immunosuppressant?

A

Elidel - pimecrolimus
Ind: atopic dermatitis
BID cream

74
Q

local anesthetic?

A

Lidoderm - lidocaine
• qday Transdermal
• Indicated for pain associated PHN
• Put one on for 12 hours, then remove for 12 hours

75
Q

osmotic laxative for constipation directions and generic/Trade?

A

polyethylene glycol 3350
MiraLax - OTC
GlycoLax - Rx

Powder for oral solution: 17 g of powder in 8 ounces of water

76
Q

bowel cleansing laxatives directions?

A
  • Powder for oral solution: drink 8 ounces of solution every 10 minutes until 4 L are consumed
  • Exception: HalfLytely is a 2 L solution
  • Contain electrolytes to replace those lost during the bowel cleansing
77
Q

bowel cleansing laxatives Trades?

A 
polyethylene glycol 3350
TriLyte
MovePrep
CoLyte
Nulytely
HalfLytely
78
Q

gastrointestinal agent Trade/generic and indications?

A

Amitiza - lubiprostone
BID
•8 mcg capsule for IBS
•24 mcg capsule for chronic constipation

79
Q

smoking cessation Trade generic and dosing?

A 
Chantix - varenicline
•	0.5 mg and 1 mg tablet
•	Day 1-3: 0.5 mg qday
•	Day 4-7: 0.5 mg BID
•	Day 8 through end of treatment: 1 mg BID
80
Q

antineoplastic agents other name, indications, counseling?

A

Aromatase Inhibitors
Ind: breast cancer Tx
o Causes an increased risk of fractures due to reduction in bone mineral density → use a bisphosphonate or calcium supplement

81
Q

Aromatase Inhibitor Trade/generics

A

Arimidex anastrozole

Femara letrozole

82
Q

Immunosupressant agents indications and Trade/generic?

A

Ind: prophylaxis of organ rejection
mycophenolate - CellCept, Sandimmune (BID)
cyclosporine - Neoral

83
Q

topical anticholinergic?

A

Transderm-Scop - scopolamine
oInd: prevention of nausea and vomiting: apply 4 hours before antiemetic effect is needed
oApply every 3 days

84
Q

Last 4 Random shit generics?

A

metoclopramide
allopurinol
febuxostat
clonidine

85
Q

metoclopramide strengths, Ind, category?

A
  • 5 mg and 10 mg tablet
  • 5 mg/5 mL syrup
  • Indicated for GERD
  • Gastrointestinal stimulant
  • For children the dose is often less than 1 mL: overdose causes extrapyramidal effects
86
Q

allopurinol Trade and Ind, category?

A

Zyloprim
Ind: gout
Xanthine oxidase inhibitor

87
Q

febuxostat Trade and dosing, Ind, category?

A

Uloric - QDay
Ind: gout
Xanthine oxidase inhibitor

88
Q

clonidine oral Trade and dosing?

A 
Catapres
•	qday
•	0.1, 0.2, 0.3 mg tablet
•	Antihypertensive
•	Do not discontinue abruptly → rebound hypertension
89
Q

clonidine transdermal Trade and dosing?

A 
Catapres TTS
•	qweek
•	0.1, 0.2, 0.3 mg/24 hours transdermal
•	Antihypertensive
•	Do not discontinue abruptly → rebound hypertension

Dispensing Final 2013 (3 decks)

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