misc gas exchange ! not part of b3.1 Flashcards
type I pneumocyte
squamous and thin
95% of alveolar surface
involved in gas exchange
very few organelles
act as tight junctions
type II pneumocyte
cuboidal
5% of alveolar surface
secrete surfactant into alveolar space
more organelles (lamellar bodies)
type II pneumocyte organelles
lamellar bodies are secretory vesicles (these secrete surfactant made of lipids + phospholipids + prevent alveoli from collapsing)
more plentiful pneumocyte
type II
Competitive and non-competitive inhibition
competitive mimics substrate and binds to enzyme at main cite, non-competitive binds to allosteric cite and alters conformation
non-competitive inhibition examples
hexokinase and glucose 6-phosphate, statin drugs
exercise on co2 production
during exercise need more atp (because skeletal muscles contract and atp fuels them) co2 is released as a byproduct
co2 production and blood ph
creates carbonic acid h2co3 by reacting with water in plasma, dissociates to H+ ions making it more acidic
ventilation feedback loop
pH sensed by chemoreceptors in aorta and carotid artery, neurons fire to action potential, signals medulla oblongata which sends signals to lungs and heart
greater blood flow, gas exchange increase
Lung and heart response to medulla oblongata
Lungs: Diaphragm and intercostal contract more rapidly to increase rate of ventilation and tidal volume, co2 decrease, pH increase
Heart: heartbeat rate increase, pump force increase
Hyperventilation occurs in response to exercise
more co2 produced = need more o2 = need more ventilation = processes increase in rate and force (forced breathing increases)