Misc.

Question 1

According to Odenweller (JVD 2019), which of the following is true?

A) The overall metastatic rate was 35% compared to 14% in previous studies.
B) 26% of lymph nodes positive for mets were negative for mets in the mandibular lymph node.
C) 73.3% of mets were in the retropharyngeal lympocentrum.
D) Labs were the most prevalent breed.

Answer 1

B is True

A is reversed, 14% mets this study compared to 35% in previous studies.

B 73.3% in mandibular LN

D) Goldens most prevalent

Question 2

Which of the following from Soltero-Rivera regarding benign and malignant proliferation of fibro-osseous and osseous lesions of oral cavity in dogs is correct?
A) Ossifying fibroma and osteoma have benign histologic behaviors, fibrous dysplasia and low grade OSA show atypia.
B) Ossifying fibroma and osteoma are well circumscribed and fibrous dysplasia and low grade OSA are ill defined.
C) Osteoma displayed bone invasion
D) Low grade OSA and fibrous dysplasia show similar expansion and invasion of osteonal canals.

Answer 2

B is correct
Only low grade OSA shows atypia
Osteoma shows more boney proliferation than invasion
Low grade OSA and fibrous dysplasia show differences in expansion and invasion of osteonal canals.

Question 3

According to Grimes (JAVMA 2019), Histo evaluation of mandibular and retropharyngeal LN in OMM and SCC, what was the prevalence of LN mets?

Answer 3

37% OMM and 27% SCC

Distant mets in 41% of OMM and only 1 dog with SCC

Question 4

According to Grimes, the retropharyngeal LN showed mets in ___ of 16 dogs and ___ had mets in the retropharyngeal LN without concurrent mets to the mandibular LN?

A) 13, 3
B) 3, 13
C) 15, 6
D) 12, 10

Answer 4

13 and 3

Mets contralateral to the tumor in 4 of 17.

Histo eval of one LN insufficient.

Question 5

According to Nemec, Erythema Multiforme and epitheliotropic T cell lymphoma, which of the following is often needed to obtain a definitive diagnosis?
A) IHC
B) Clonality
C) Repeated biopsy
D) Clinical follow-up

Answer 5

All of them, histopath alone is not always diagnostic.

Question 6

In Fiani, Osteoma of oral and maxillofacial region of cats, which of the two types of osteoma was often productive pattern, more expansive, less well marginated with destruction of adjacent bone.
A) Compact
B) Cortical
C) Cancellous
D) Peripheral

Answer 6

C) Cancellous (or endosteal)

Compact and Cortical describe the other version. This can be called peripheral in humans (and by Volker). This is productive, globular, well marginated with smooth borders.

Mand most common site in cats

Question 7

Volker, Osteoma in 6 dogs, what are the 2 forms of osteoma?

Answer 7

Peripheral arise from periosteum, slow growing and can be pedunculated

Central can displace teeth or expand bone

Don’t cause bone loss or lysis, no malignant transformation or mets.

Question 8

According to Smithson, oral plasmacytoma in 3 dogs, which of the following is false?
A) Cutaneous and oral extramedullary plasmacytomas are benign with surgical excision being curative.
B) Multicentric plasmacytoma does not increase risk of systemic disease
C) Plasmacytomas represent 1% of all canine oral tumors
D) Developement of one plasmacytoma may be risk factor for another.

Answer 8

C) 5% of all oral tumors

Unknown if multicentric or mechanical transfer from occlusion when seen in both mandible and maxilla.

Question 9

According to Nemec, Types of TR in tumors, which of the following is true?
A) Teeth at distant sites from tumors are 5x more likely to have ESR
B) Teeth at distant sites from tumors are 83x more likely to have EIR
C) ERR most likely at sites distant from non-odontogenic tumors
D) OSA, all teeth with TR had ERR

Answer 9

Teeth at distant sites 3.2x more likely to have ESR

B is correct

C) EIR most likely at distant sites from non-odontogenic tumors

D) OSA all teeth with TR had EIR.

Question 10

According to Nemec, Types of TR in tumors, which of the following is true?
A) Oral tumors may cause ESR at sites of teeth at tumor site and at distant sites.
B) Teeth at tumor sites with non-odontogenic tumors had EIR significantly more than teeth with odontogenic tumors
C) TR in dogs with CAA and POF had ESR commonly in quads distant to the tumor
D) There was significant difference between odontogenic and non-odontogenic TR with regards to overall presence of TR.

Answer 10

B is true

A) oral tumors cause EIR at sites of tumor and distant sites

C) POF and CAA associated with ERR at distant sites

D) There was no significant difference between odontogenic and non-odoentogenic tumors with regard to overall presence of TR

Question 11

In Eubanks, what was the most important prognostic indicator regarding MLO?

Answer 11

Location

Question 12

Regarding MLO, which of the following is false?
A) Tumor is covered with a tough fibrous membrane
B) Most are cured by complete excision
C) Brush pattern along tumor borders may suggest malignant change.
D) MLO typically infiltrates into adjacent soft tissue.

Answer 12

D)

Question 13

According to Hillman, Biological behavior of oral and perioral MCT, what percent showed regional LN metastasis?
A) 59%
B) 15%
C) 7%
D) 43%

Answer 13

A) 59%

Question 14

According to Hillman, Biological behavior of oral and perioral MCT, which of the following was true?
A) CCR7 was significantly associated with presence of regional LN mets
B) MST was 52wk
C) If MCT is in oral mucosa, oral MCJ or perioral region, LN mets at the time of diagnosis is a negative prognostic indicator
D) Oral MCT is less aggressive than cutaneous MCT

Answer 14

C) is true though long ST can still be obtained when regional LN mets are present

A) CCR7 not significantly associated
B) MST 52mo
D) given 59% regional LN mets, oral MCT is considered more aggressive.

Question 15

According to Culp, Surgical excision and factors associated with ST in lingual neoplasia, what was the most common lingual tumor?
A) OMM
B) SCC
C) MCT
D) HSA

Answer 15

SCC (32%)>OMM(30%)>MCT>HSA

Question 16

According to Culp, Surgical excision and factors associated with ST in lingual neoplasia, what was the most common location of lingual tumors?
A) body and dorsal
B) apex and ventral
C) root and dorsal
D) body and root, dorsal and ventral

Answer 16

Body most common (28%), followed closely by root (26%) and apex (23%) (body and root 10%)

Dorsal most common at 57% with ventral 21% and dorsal and ventral at 23%

Question 17

According to Culp, Surgical excision and factors associated with ST in lingual neoplasia, which of the following is false?
A) overall 19% met rate
B) ST times significantly different for dogs with feeding tubes, met disease, tumor>2cm and age.
C) Compared with other studies, the OMM met rate was less at 38%.
D) Dogs without mets lived 7x longer.

Answer 17

D) is incorrect, dogs without mets lived 3x longer

Previous OMM met rate published was 53%

Small dogs with tumor sizes <2cm lived 4x longer than dogs with larger tumors.

Question 18

According to Bonfati, diagnostic value of cytologic analysis, what yielded the highest overall agreement for all lesions?
A) FNI 
B) FNA
C) Impression smear
D) Your Mom

Answer 18

A) FNI (87% overall, 83% oral lesions)

They threw out non-diagnostic samples so this paper is over exaggerated. They say “cannot replace histo” but if you get a diagnostic sample it tends to have very high sensitivity and specificity.

Question 19

According to Conguista variability in recommendations for cervical LN pathology for staging of oral disease, which of the following in incorrect?
A) Extirpation and histopath is most commonly recommended for clinical confirmation of mets.
B) Elective neck dissection of LN to confirm clinical diagnosis is significantly associated with tumor type.
C) Bilateral removal of mandibular and retropharyngeal LN recommended more often for SCC than OMM and FSA.
D) Recommendations for elective neck dissection of LN increase with increase in tumor size.

Answer 19

C) OMM most recommended followed by SCC and FSA

Question 20

According to Conguista variability in recommendations for cervical LN pathology for staging of oral disease, which of the following in incorrect?
A) Academic institutions were significantly more likely to recommend elective neck dissection of LNs than private practitioners in T1-T3 OMM, T3 OSCC and T2 FSA and MCT.
B) Elective neck dissection not routinely recommended.
C) 25-38% recommend elective neck dissection of LNs when confirming mets for OMM.
D) Elective neck dissection of LN to confirm clinical diagnosis is significantly associated with tumor type.

Answer 20

C) 25-38% recommend elective neck dissection of LNs when confirming clinical diagnosis in OMM.