Misc 3 Flashcards

1
Q

Factor V leiden

A

activated protein C resistance

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2
Q

Factor V leiden

A

higher risk VTW

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3
Q

Corrigans sign

A

Aortic regurg

bounding and forceful , rapidly increases then collapses

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4
Q

Narrow pulse pressurew

A

AStenosis

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5
Q

Aortic stenosis sx

A
Syncope
Angina
Dyspnea on exertion
Chest pain
Ejec systolic - valsalva
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6
Q

AS ft

A
narrow pulse P
slow rising pulse
thrill @ apex
4th heart sound (LVH)
soft S2
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7
Q

AS causes

A

degenerative
bicupsid valve
rheumatic

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8
Q

Monitor in amiodarone

A

TFTs

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9
Q

Nephrotic triad

A

proteinuria
edema
hypoalbumin

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10
Q

Nephrotic in HIV/IVDU

A

Focal segmental

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11
Q

Cluster headache tx

A

subcut sumatriptan + 100% O2

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12
Q

Amlodipine

A

CCB

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13
Q

First line BP >55

A

CCB - amlodipine

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14
Q

de Quervain’s thyroiditis

A

brief hyper followed by long hypo

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15
Q

Hyperthyroid

A

Grave’s

Toxic multinodular goitre

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16
Q

Hashimotos

A

most common hypo

autoimmune (IDDM, Addisons, pernicious anemia)

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17
Q

MEN 1 sx

A

parathyroid tumour
pancreatic tumour
pituitary tumour

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18
Q

MEN 2 sx

A

medullatry thyroid ca
pheochromocytoma
parathyroid tumout

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19
Q

Phaeochromocytoma sx

A
sweat
headache
palpitations
HTN
Anx
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20
Q

Phaeochromocytoma IX

A

urinary metanephrines

if high –> CT CAP

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21
Q

Phaeo tx

A

stabilize w alpha-blocker (phenoxybenzamine) then a BB (propranolol) the surgery

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22
Q

Antiphospholipid syndroms test

A

anticardiolipin

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23
Q

Polymyositis Ab

A

Anti-Jo 1

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24
Q

HLA B27

A

ank spond
reactive arthritis
enteropathic arthritis (IBD)
psoriatic arthritis

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25
Q

Bechet’s disease Ab

A

HLA B51

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26
Q

Adrenaline in cardiac arrest

A

1mg (10 ml 1:10,000) or 1ml 1:1000)

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27
Q

Shockable rhytms

A

pulseless v tachy

ventricular fib

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28
Q

false negative mantoux

A

sarcoidosis
steroids
lymphoma
AIDS

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29
Q

Pernicious anemia test

A

intrinsic factor Ab

Low B12

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30
Q

Drugs inducing lupus

A

isoniazid
infliximab
carbamazepine

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31
Q

Drug induced lupus Ab

A

Anti histone

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32
Q

FEV1/FVC in obstructive

A

Low

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33
Q

FEV1/FVC in restrictive

A

Norm or high

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34
Q

PFTs obstructuve

A

EVERYTHING low

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35
Q

Obstructibe lung diseases

A
COPD
Asthma
emphysema
bronchiectasis/CF
Chronic bronchitis
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36
Q

Restrictive lung dx

A
ILD
interstitial pneumonia
pneumoconiosis
sarcoidosis
Chest wall NMD
Obesity
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37
Q

Lamotrigine SE

A

stevens johnson
within 2 months of new med
prodromal flu like illness

38
Q

Angina mgmt

A

1) lifestyle
2) statin + aspirin
3) bb or ccb
(ccb alone- verapamil/diltiazem, in combo w bb - nifedipine)
4) bb + ccb

39
Q

Big rise in ALP and GGT than in ALT

A

obstructive jaundice

- no pain - pancreatic Ca

40
Q

Panless jaundice of pancreatic Ca

A

pale stools, dark urine, pruritus

41
Q

COurvoisiers law

A

in presence of painless obstructive jaundice, palpable gallbladder unlikely fue to gallsones

42
Q

Nephrogenic DI water rest

A

Low urine osmol after water deprivation

Low after desmopressin too

43
Q

Cranial DI

A

low after ware dep

high after desmopressin

44
Q

autoimmune hep Ab

A

anti smooth muscle ab

anti nuclear ab

45
Q

necrosis marker

A

lactate dehydrogenase (LDH)

46
Q

Wegners granulomatosis marker

A

cANCA

47
Q

ALT/AST raised more than ALP

A

autoimmune hep

48
Q

Raised ALP

A

bile duct pathology

49
Q

primary biliary cirrhosis Ab

A

antimitochondiral ab

50
Q

URTI sx + amox = rash

A

gandular fever

51
Q

Homonymous hemianopia w macular sparing

A

occipital cortex

52
Q

tunnel vision, fhx of early blindness

A

retina - retinitis pigmentosa

53
Q

left homonymous hemianopia

A

lesion of right optic tract

54
Q

homonymous quadrantanopia

A

inferior quad- parietal optic radiations

Superior quad - temp optic radiations

55
Q

Correct hyponatremia too fast

A

central pontine myelinolysis

56
Q

Kid w pyloric stenosis electrolytes

A

hypochloremic hypokalemic met alk.

57
Q

V high AST and ALT

A

cirrhosis

58
Q

AST higher than ALT

A

alcoholic liver

59
Q

Urea higher than the raised Cr

A

dehydration

60
Q

Glicazide SE

A

hypoglycemia

61
Q

Glitazones SE

A

HF

62
Q

ptosis + dilated pupil

A

3rd nerve palsy

63
Q

ptosis + constricted pupil

A

horners

64
Q

IgA nephropathy

A

v recent URTI followed by symptoms in young person

65
Q

Nephritic triad

A

hematuria
oliguria
HTN

66
Q

Neprhotic triad

A

hypoalbumin
proteinuria
edema

67
Q

Post strep glomerulonephritis

A

7-14d post URTI

68
Q

Prolactnioma tx

A

Carbergoline/bromocriptine (dop agonist) first line

2nd: surgery

69
Q

malignancy + raised CK

A

polymyositis

70
Q

acne rosasea tx

A

topical metronizadole

oral tetracyclie

71
Q

Hemochromatosis bloods

A

raised transferrin
raised ferritin
low TIBC

72
Q

Primary hyperaldosteronism ft

A

HTN
Hypokalemia (muscle weakness)
Alkalosis

73
Q

RAPD + unilaterally dilated pupil

A

optic nerve injury

74
Q

bilat ptosis + bilat contricted

A

opiate OD

75
Q

refeeding syndrome bloods

A

low K
low Mg
low Phos

76
Q

MRCP beaded appearancw

A

Primaru sclerosing cholangitis

77
Q

CSF: low gluc, high prot, high polymorphs

A

bacterial meningitis (Strep pneumo, neisseria)

78
Q

Male, tall, high LH, low test

A
Klinefelter's
Primary hpogonasism (low test due to testicular failure, high FSH/LH because no neg fb)
79
Q

Soft S1

A

long PR

MR

80
Q

Loud S1

A

Mitral stenosis

81
Q

Soft S2

A

aortis stenosis

82
Q

S4

A

AS, HOCM, HTN

83
Q

S3

A

normal <30

LVF (dilated cardiomyopathy), pericarditis, mitral regurg

84
Q

Acute close angle glaucoma

A

severe pain (ocular or headache)
decreased vision, haloes
semi-dilated pupil
hazy cornea

85
Q

Anterior uveitis

A

acute
pain
blurry/photophobe
small fixed oval pupil, ciliary flush

86
Q

Scleritis

A

Severe pain, worse on mvmt, tenderness

RA or autoimmune

87
Q

Conjunctivitis

A

purulent disharge - bact

clear discharge - viral

88
Q

Subconj hem

A

history of trauma, cough, vom, constip

89
Q

Endophtha;mitis

A

red eye, pain, visual loss folloinw eye surgery

90
Q

Upper lung firbosis

A
pneumonitis
coal workers lung
silicosis
sarcoidosis
TB
ank spond
91
Q

Lower lung fibrosis

A

Idiopathyc
connective tissue (SLE)
Drugs
asbestosis