Immunology

Question 1

Skin prick test used fr

Answer 1

Food, pollen
Most common, inexpensive
Wheal will form in allergy

Question 2

RAST (radioallergosorbent test)

Answer 2

Determined amt IgE reacting w allergens
Food, inhaled (pollen), wasp/bee
Done when skin prick not suitable - like extensive eczema or if pt on antihistamines

Question 3

Skin patch test

Answer 3

Contact dermatitis - 30-40 allergens placed on back, patched removed 48hr later and then results red 48 hour after.
Nickel

Question 4

Adult doses for anaphylaxis

Answer 4

Adren: 500 mcg (.5ml 1:1000)
Hydro: 200mg
Chlor: 10mg

Question 5

6-12y anaphylaxis doses

Answer 5

Adren: 300mcg (.3ml 1:1000)
Hydro: 100mg
Chlor: 5mg

Question 6

Oral allergy syndrome

Answer 6

linked w pollen allergies, seasonal variation.
IgE mediated toward specific RAW fruits/veggies/nuts/spices (commonly raw veggies like carrots)
Cross reactivity w non-food allergies (like Birch)
Mostly lips/tongue/mouth/throat. Non systemic

Question 7

0-6y anaphylaxis dose

Answer 7

Adren: 150mcg (.15ml)

Question 8

What blood marker rises after anaphylaxis

Answer 8

Serum tryptase, remains high up to 12h