Misc Flashcards

1
Q

BO causes tx

A

Infection
Gord
Drugs non compliance
Hal mismatch

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2
Q

BO treatment

A

Treat cause

Tax and aza to MMf

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3
Q

Curschmann spirals

A

Mucus plugs
Eo asthma

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4
Q

Sulphur granules

A

Actinomycosis

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5
Q

Pleural fibroma

A

Raised GnRH
Raised bHCG
IGF2

HPOA
Gynaecomastia
Low BM

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6
Q

AVM

A

Abnormal communication PA and PV so RtoL shunt

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7
Q

AVM risk factor

A

HHT
aD

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8
Q

AVM CX

A

25% CVA
10% haemorrhage
Brain abscess
Haemothorax
Maternal death 1%
Phtn

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9
Q

Management AVM

A

Indication all seen refer embolisation
CI IR - pregnant, PH, renal impairment

Medical
O2 and bed rest
Venesection HCT more than 55 AND symptoms hyperviscosity
6m CT and ABG, aspirin, abx prophylaxis

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10
Q

Ocular TB

A

T cells eyes cross react MTB

Change VA
IGRA positive
RF TB

6m to 1y tx
Ethambutol to moxifloxacin
+- pred depends on opthalmology

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11
Q

Sarcoidosis stages

A

0 nil
1 BHL
2 BHL and parenchyma, change
3 just parenchyma change
4 fibrosis

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12
Q

Indication steroids sarcoid

A

Fatal
Organ dysfunction
QOL affected

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13
Q

DMARD sarcoid

A

MTX or AZA

Indication
Steroid not working
Not able to taper
CX steroid
Pt wishes

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14
Q

Hypoxia and flying

A

Indication
Sats less than 95% and
- Hx Hypercapnia with T2RF
- Copd mrc 3 and on 6wt Sats less than 84%
- severe asthma
- Ild with pao2 less than 9.4 or TLCO less than 50%
- severe chest wall deformity and fvc less than 1 or unable spiro 6wt
- NYHA 3/4 heart failure
- CF fev1 less than 50% and HCT less than 90% Sats

Perform hypoxia challenge
Pa02 less than 6.6 or Sats less than 85%
Then 2L or add 2L

VTE no fly 2w
Ptx 7 days post treatment and resolution
TB 2x smear negative or no info negative 2w or MDR 2 negative samples. Extrapulmonary no restriction
Pneumonia less than 94% then 7d
Don’t flu with flu mers mm chicken pox sars covid
Thoracic surgery 2w essential and otherwise 4w
OM for 2w

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15
Q

No air travel

A

Chemo
Resp failure
Untreated Ptx
Acute infection - TB mers sars covid
Bromchogenic cyst
Cerebral air embolus
More than 4L o2

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16
Q

VTE and flying

A

Ensure hydration
No etoh
Mobile
Compression
high risk then LMWH or DOAG

High risk
Previous VTE
Thrombophilia
6 weeks major surgery
Malignancy

17
Q

Drugs

A

Tacrolimus or cyclosporine calcineurin inhibitor - inhibit il2 and ifn gamma
Aza purine synthase inhibitor
MMF in liver deplete t and b lymphocytes
Pred affects humoral and cellular preventing gene transcription
Sirolimus mTOR inhibitor
Cyclophosphamide causes cellular apoptosis
Aza - pro drug 6 mecaptopurine
Ritux anti CD20
Infliximab anti tnf

18
Q

High o2 harmful

A

Co2 retainer
MI
Paraquat poisoning
Bleomycin injury

19
Q

BMI lower target Sats

20
Q

Po2 less than 7

A

Sats ,ess than 85%

21
Q

Live vaccine

A

MMR
BCG
Yellow fever
Oral polio
Oral typhoid

22
Q

Immunoglobulin indication

A

Iss and vzv or measles

23
Q

Hold AZT or MTX bloods

A

WCC less than 3
Plt less than 100
ALP or ALT more than 3x

24
Q

TPMT percentage

A

Avoid if more than 0.3%

25
Pao2 forumula
Fio2 x 0.75
26
Duchene
1/3500 male births X linked Present teenage
27
Breathlessness centre
Insular cortex
28
Arterial supply pleura
Cervical subclavian Costcovert intercostal Diaphragmatic vascular plexus diaphragm Parietal bronchial
29
Openings diaphragm
IVC T8 Oeso T10 Aorta T12
30
Charcot-Leyden crystals
Breakdown eosinophilia granules Needle or diamond shaped crystals in sputum
31
Cough receptor
TRPV1 increased is capsaicin sensitive Increased in cough hypersensitivity syndromes