Misc Flashcards

1
Q

Aortic stenosis in pregnancy

A

Maintain AFTERLOAD! avoid hypotension, avoid tachycardia!

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2
Q

Mitral stenosis in pregnancy

A

AVOID AFIB! DIURESIS TO AVOID PULM EDEMA. treat with beta blockade

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3
Q

teratogenicity of mycophenolate associated with”

A

microtia, cleft lip and palate, cardiac defect

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4
Q

informed consent, ethical principle of?

A

autonomy

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5
Q

After prolonged pushing, pt. suffers foot drop, which nerve is affected

A

peroneal nerve

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6
Q

what cytokines are most likely involved in septic shock?

A

TNF alpha, IL-1

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7
Q

most commonly acquired congenital viral infection

A

CMV

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8
Q

what infectious agent which caused IUFD associated with placental abscesses

A

listeria

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9
Q

what type of twins with cleavage at day 5?

A

MCDA

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10
Q

how to diagnose ARDS?

A

new or worsening respiratory symptoms with bilat opacities not fully explained in vented patient with PEE> 5 … PaO2/FIo2 < 300!

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11
Q

highest yield in determining cause of stillbirth

A

placental pathology

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12
Q

how to get karyotype after IUFD for most likelihood of results

A

amniocentesis

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13
Q

precursor of placental estrogen?

A

DHEAS

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14
Q

precursor of placental progesterone

A

cholesterol

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15
Q

what enzyme does fetus have that placental does NOT for steroid synthessis?

A

17 alpha hydroxylase (biosynthesis of cortisol and androgens)

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16
Q

most common fetal effect in untreated PKU?

A

intellectual disability

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17
Q

PRECONCEPTION W/ TRANSPLANT- tell patients… most likely good outcome

A

creatinine level < 1.5

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18
Q

most prevalent aneuploidy with CDH?

A

Trisomy 18

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19
Q

Hardy weinberg dizease frequency of mutation

A

q2

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20
Q

carrier frequency?

A

2PQ

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21
Q

why dont we use nitroprusside?

A

reflex tachycardia, cyanide toxicity

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22
Q

CCB adverse drug effect

A

Headache, hypotension, peripheral edema, flushing

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23
Q

causes of low estriol?

A

placental steroid sulfatase deficiency, smith lemli opitz, CAH, anencephaly

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24
Q

how to monitor improvement in DKA

A

anion gap

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25
Q

surfactant has highest concentration of what phospholipid

A

PHOSPHOTIDYLCHOLINE (aka lecithin)

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26
Q

dermatosis with worst pregnancy outcome?

A

impetigo herpetiformis

27
Q

what is the most common sex chromosome aneuploidy?

A

Klinefelter XXY

28
Q

NT alone has sensitivity of what for dx of T21?

A

70%

29
Q

what anatomic finding most associated with T21?

A

absent nasal bone/hypoplastic nasal bone

30
Q

myelomeningocele MOMS in utero repair most benefit

A

decrease need for shunt placement

31
Q

ADE of CCB?

A

peripheral edema, headache, hypotension

32
Q

most confirmatory of primary CMV infection?

A

increasing IgG titer, 2-4 fold

33
Q

amnio acid transport across the placenta by?

A

active transport

34
Q

Medications most likely to be passed through breast milk?

A

lipid soluble

35
Q

what cytokines are antiinflammatory

A

IL 10, IL 4

36
Q

What cytokines are PRO inflammatory

A

IL 6, IL 8, TNF alpha, Interferon

37
Q

what does an ROC curve represent?

A

diagnostic ability of binary classifier, True positive rate (SENSITIVITY) against false pOS rate (1-SPEC)

38
Q

HYPERemesis with tingling/numbness/confusion… what do you need?

A

Thiamine! B1! wernickes enceph

39
Q

what is the most likely complication from first trimester varicella infection

A

NOTHING! risk is very low@

40
Q

in the intervillous space, maternal blood in contact with?

A

syncitiotrophoblasts

41
Q

US feature with fetal alcohol syndrome?

A

microcephaly

42
Q

mitral stenosis most likely to decompensate postpartum due to?

A

increased preload

43
Q

which crosses thyroid molecule placenta most rapidly

A

TRH

44
Q

PaO2 in the umbilical artery is approximately?

A

20

45
Q

which vessel has the most oxygenated blood?

A

umbilical vein –> ductus venosus

46
Q

best treatment for pheochromocytoma in pregnancy?

A

alpha blocker (phenoxybenzamine)

47
Q

what infection is most likely associated with PVL?

A

chorioamnionitis

48
Q

wedge pressure is indicative of?

A

LV preload

49
Q

mechanism of action for beta agonist?

A

activation of adenyl cyclase, which then increases cAMP, activate PKP, reduce Ca+2, prevent smooth muscle contraction

50
Q

for whcih infection does prenatal treatment prevent transmission to fetus?

A

hepatitis B

51
Q

which prostaglandin relaxes the uterus

A

prostacyclin

52
Q

renal dosing for dopamine

A

4 *(less than 5!)

53
Q

what type of connections are most protective in TTTS?

A

AA

54
Q

how do you compare multiple MEANS

A

anova

55
Q

How do you treat listeria? what about if PCN allergic?

A

Amoxicillin/Bactrim

56
Q

what steroid most associated with sodium resorption?

A

fudrocortisone

57
Q

what antibiotic potentiates the neuromuscular blockade effect of magnesium?

A

gentamycin

58
Q

what is the most common complication of malaria in pregnancy? plasmodium falciparum

A

maternal anemia

59
Q

ductus arteriosus receives blood from?

A

pulmonary artery

60
Q

when to intubate pregnant patient?

A

PaCO2 > 40

61
Q

PFT: what increases in pregnancy?

A

TV, IC, pO2, alveloral vent

62
Q

PFTs: what decreases in pregnancy?

A

TLC, ERV, FRC, RV, pCO2

63
Q

what is the most common complication of prematurity

A

respiratory distress syndrome