Misc Flashcards
Aortic stenosis in pregnancy
Maintain AFTERLOAD! avoid hypotension, avoid tachycardia!
Mitral stenosis in pregnancy
AVOID AFIB! DIURESIS TO AVOID PULM EDEMA. treat with beta blockade
teratogenicity of mycophenolate associated with”
microtia, cleft lip and palate, cardiac defect
informed consent, ethical principle of?
autonomy
After prolonged pushing, pt. suffers foot drop, which nerve is affected
peroneal nerve
what cytokines are most likely involved in septic shock?
TNF alpha, IL-1
most commonly acquired congenital viral infection
CMV
what infectious agent which caused IUFD associated with placental abscesses
listeria
what type of twins with cleavage at day 5?
MCDA
how to diagnose ARDS?
new or worsening respiratory symptoms with bilat opacities not fully explained in vented patient with PEE> 5 … PaO2/FIo2 < 300!
highest yield in determining cause of stillbirth
placental pathology
how to get karyotype after IUFD for most likelihood of results
amniocentesis
precursor of placental estrogen?
DHEAS
precursor of placental progesterone
cholesterol
what enzyme does fetus have that placental does NOT for steroid synthessis?
17 alpha hydroxylase (biosynthesis of cortisol and androgens)
most common fetal effect in untreated PKU?
intellectual disability
PRECONCEPTION W/ TRANSPLANT- tell patients… most likely good outcome
creatinine level < 1.5
most prevalent aneuploidy with CDH?
Trisomy 18
Hardy weinberg dizease frequency of mutation
q2
carrier frequency?
2PQ
why dont we use nitroprusside?
reflex tachycardia, cyanide toxicity
CCB adverse drug effect
Headache, hypotension, peripheral edema, flushing
causes of low estriol?
placental steroid sulfatase deficiency, smith lemli opitz, CAH, anencephaly
how to monitor improvement in DKA
anion gap
surfactant has highest concentration of what phospholipid
PHOSPHOTIDYLCHOLINE (aka lecithin)
dermatosis with worst pregnancy outcome?
impetigo herpetiformis
what is the most common sex chromosome aneuploidy?
Klinefelter XXY
NT alone has sensitivity of what for dx of T21?
70%
what anatomic finding most associated with T21?
absent nasal bone/hypoplastic nasal bone
myelomeningocele MOMS in utero repair most benefit
decrease need for shunt placement
ADE of CCB?
peripheral edema, headache, hypotension
most confirmatory of primary CMV infection?
increasing IgG titer, 2-4 fold
amnio acid transport across the placenta by?
active transport
Medications most likely to be passed through breast milk?
lipid soluble
what cytokines are antiinflammatory
IL 10, IL 4
What cytokines are PRO inflammatory
IL 6, IL 8, TNF alpha, Interferon
what does an ROC curve represent?
diagnostic ability of binary classifier, True positive rate (SENSITIVITY) against false pOS rate (1-SPEC)
HYPERemesis with tingling/numbness/confusion… what do you need?
Thiamine! B1! wernickes enceph
what is the most likely complication from first trimester varicella infection
NOTHING! risk is very low@
in the intervillous space, maternal blood in contact with?
syncitiotrophoblasts
US feature with fetal alcohol syndrome?
microcephaly
mitral stenosis most likely to decompensate postpartum due to?
increased preload
which crosses thyroid molecule placenta most rapidly
TRH
PaO2 in the umbilical artery is approximately?
20
which vessel has the most oxygenated blood?
umbilical vein –> ductus venosus
best treatment for pheochromocytoma in pregnancy?
alpha blocker (phenoxybenzamine)
what infection is most likely associated with PVL?
chorioamnionitis
wedge pressure is indicative of?
LV preload
mechanism of action for beta agonist?
activation of adenyl cyclase, which then increases cAMP, activate PKP, reduce Ca+2, prevent smooth muscle contraction
for whcih infection does prenatal treatment prevent transmission to fetus?
hepatitis B
which prostaglandin relaxes the uterus
prostacyclin
renal dosing for dopamine
4 *(less than 5!)
what type of connections are most protective in TTTS?
AA
how do you compare multiple MEANS
anova
How do you treat listeria? what about if PCN allergic?
Amoxicillin/Bactrim
what steroid most associated with sodium resorption?
fudrocortisone
what antibiotic potentiates the neuromuscular blockade effect of magnesium?
gentamycin
what is the most common complication of malaria in pregnancy? plasmodium falciparum
maternal anemia
ductus arteriosus receives blood from?
pulmonary artery
when to intubate pregnant patient?
PaCO2 > 40
PFT: what increases in pregnancy?
TV, IC, pO2, alveloral vent
PFTs: what decreases in pregnancy?
TLC, ERV, FRC, RV, pCO2
what is the most common complication of prematurity
respiratory distress syndrome
