2019

Question 1

what placental enzyme breaks down betamethasone

Answer 1

11beta-hydroxysteroid dehydrogenase type 2

Question 2

genetic anticipation

Answer 2

s/sx become more severe or appear earlier in subsequent generations

Question 3

what happens to plasma osmolality in pregnancy

Answer 3

decreases to new set point, plasma sodium dec as well

Question 4

Pregnancy complicated by abdominal pain, cardiac arrythmia, gastric ulcer- what hormone elevated

Answer 4

Parathyroid. increase in Ca and Phos. Increased Calcium leads to increased gastrin secretion and PUD

Question 5

what molecule has higher net excretion in pregnancy than outside?

Answer 5

glucose- why! impared reabsorption in the loop of henle

Question 6

Maximum dose of labetalol in 24 hours

Answer 6

220 mg/24 hr

Question 7

maximum dose of hydralazine in 24 hours

Answer 7

25 mg/24 hr

Question 8

when is vertical transmission of CMV highest

Answer 8

T3

Question 9

maternal pH in DKA?

Answer 9

< 7.3

Question 10

why peritoneal dialysis over hemodialysis ?

Answer 10

Less fluctuations in BP, no anticoag required

Question 11

goal for initial resuscitation of patient in septic shock?

Answer 11

IV Abx within 1 hour

Question 12

midgut herniation would not be normal after CRL of?

Answer 12

54mm

Question 13

SGA/Nasal hypoplasia/ stippled epiphyses, hydrocephalous cataracts is associated with?/

Answer 13

WARFARIN EXPOSURE

Question 14

TIME PERIOD FOR NEURAL TUBE CLOSER

Answer 14

21 to 28 days post concepction

Question 15

rate of transmission of CMV after a primary infection in pregnancy

Answer 15

30-50%

Question 16

what is best statistical test to assess your primary outcome (time to delivery) with adjustment for confounders?

Answer 16

cox proportional hazard curve

Question 17

case control study good for?

Answer 17

rare outcome

Question 18

what organism causes UTI in those with alkaline urine?qq

Answer 18

proteus

Question 19

population prevalence of CF carrier in caucasian population

Answer 19

1/25

Question 20

history of prior pregnancy with hemolytic disease of the newborn, new partner, how do you know the risk?

Answer 20

fetal antigen status

Question 21

cell free DNA fetal antigen testing needs wHAT to be valid?

Answer 21

more than 6 of 92 SNPs must differ between mother and fetus, if not- repeat test in 4-6 weeks

Question 22

most common structural anomalies with 22q11 del

Answer 22

cleft palate and interrupted aortic arch

Question 23

describe chest x ray in TTN

Answer 23

prominent perihilar streaks which represent engorged pulmonary lymphatics and BVs

Question 24

describe chest x ray in respiratory distress syndrome

Answer 24

low-volume lungs with diffuse reticulogranular pattern and air bronchograms

Question 25

most important clinical benefit for delayed CC in preterm infant

Answer 25

50% decrease in IVH

Question 26

characteristics of congenital rubella syndrome

Answer 26

deafness, cataracts, supra valvular pulmonic stenosis (pathognomic)

Question 27

what interventions should you offer for pprom less than 22 weeks

Answer 27

latency antibiotics; no BMZ, GBS proph, mag for NP, or tocolytics

Question 28

benefit of magnesium for NP?

Answer 28

decreases the risk of CP or death

Question 29

what is the incidence of stillbirth per thousand 1 week after BPP 8/8 (modified or reg BPP)

Answer 29

0.8

Question 30

what is the incidence of still birth per thousand 1 week after NST

Answer 30

1.9

Question 31

LBCVA associated with?

Answer 31

persistent left SVC

Question 32

premutation number of repeats

Answer 32

55-200

Question 33

IHSS inheritance

Answer 33

AD

Question 34

what hormones favor sodium excretion

Answer 34

progesterone (inhibits aldosterone), atrial natriuretic protein, vasodilatory prostaglandins

Question 35

hormones that promote sodium reabsorption

Answer 35

aldosterone, deoxycortisone, estrogen