Misc Flashcards
What is a type 1 hypersensitivity reaction?
Reaction mediated by IgE antibodies
What is a type 2 hypersensitivity reaction?
Cytotoxic reaction mediated by IgG or IgM antibodies
What is a type 3 hypersensitivity reaction?
Reaction mediated by immune complexes
What is a type 4 hypersensitivity reaction?
Delayed reaction mediated by cellular response
T-cell mediated
Onset of type 1 hypersensitivity reaction?
Immediate -> allergy, anaphylaxis & atopy
Onset of type 2 hypersensitivity reaction and examples?
Hours to days
Haemolytic disease of the newborn
Autoimmune haemolytic anaemia
Goodpasture’s syndrome
Onset of type 3 hypersensitivity reaction and examples?
Hours, days or weeks
Serum sickness
Rheumatoid arthritis (RA)
Systemic lupus erythematosus (SLE)
Post-streptococcal glomerulonephritis
Onset of type 4 hypersensitivity reaction and an example?
Delayed hypersensitivity, occurs 24-72 hours after antigen exposure
Contact dermatitis