Misc Flashcards

1
Q

What is a type 1 hypersensitivity reaction?

A

Reaction mediated by IgE antibodies

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2
Q

What is a type 2 hypersensitivity reaction?

A

Cytotoxic reaction mediated by IgG or IgM antibodies

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3
Q

What is a type 3 hypersensitivity reaction?

A

Reaction mediated by immune complexes

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4
Q

What is a type 4 hypersensitivity reaction?

A

Delayed reaction mediated by cellular response
T-cell mediated

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5
Q

Onset of type 1 hypersensitivity reaction?

A

Immediate -> allergy, anaphylaxis & atopy

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6
Q

Onset of type 2 hypersensitivity reaction and examples?

A

Hours to days

Haemolytic disease of the newborn
Autoimmune haemolytic anaemia
Goodpasture’s syndrome

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7
Q

Onset of type 3 hypersensitivity reaction and examples?

A

Hours, days or weeks

Serum sickness
Rheumatoid arthritis (RA)
Systemic lupus erythematosus (SLE)
Post-streptococcal glomerulonephritis

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8
Q

Onset of type 4 hypersensitivity reaction and an example?

A

Delayed hypersensitivity, occurs 24-72 hours after antigen exposure

Contact dermatitis

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