Minerals Flashcards
Define mineral
Inorganic element requires as nutrients
What are the 2 groups of of minerals and define them?
Macrominerals: required in greater proportions by animals
Microminerals: required in small proportions by animals
Calcium functions?
- second messenger
- enzyme activator
- bone mineralization
Calcium deficiencies?
Hypocalcemia in cows
Milk fever
Parturient pariesis
Calcium regulations has how many pathways?
2
what are the 2 pathways of absorption?
- Passive: between cells and the tight junction. Diffusion of Calcium (high to low concentration)
- Active transport: In the brush boarder (TRPV 6 and TRPV 5). Mobilized from the lumen to the cytosol in the cell; to the basal membrane. From there, (1) PMCA to transported to the outside (2) NCX1 transport in basal membrane. Transport Ca OUTSIDE and Na INSIDE.
Functions of phosphorous
- bone mineralization
- oxidative phosphorylation
- Acid-base buffer
- DNA and RNA
- Phospolipids
- Singaling molecules
- Reversable modiciation of proteins
- Enzymatic reactions
Deficiency of phosphorous can be seen via?
Rickets
PICA: when animals are picking on things; will start chewing rocks or wood; it can happen when an animal does not recieve enough phosphorous or fiber— behavioral changes; animals are trying to find it in the ground.
Ca:P ratio
They are mobilized together for mineralization. IF NOT ENOUGH phos. proivded, animals won’t be able to deposit Ca in the bones, and leads to issues.
Functions of Magnesium
- Anion charge neutralization
- Cellular energy metabolism
- Nucleic acid and protein synthesis
- Second messenger
- Ion channels
Deficiences of Mg can be seen via?
Grass tetany
convulsions
muscle twitching
Sodium, Potassium, and Chloride are what?
Electrolytes: improve acid base balance in cells
Functions of Na, K, and Cl?
- nutrient transport
- membrane potentials
- extracellular fluid volume
Deficiences of Na+, Cl, K are seen as?
- Irregular heartbeat
- Vomiting
- Diarrhea
Iodine function?
Thyroid hormone synthesis
Defiecieny of Iodine can be seen via?
Goiter: mass in the trachea, the lining where the tyroid gland is
What is the function of selenium?
- Selenoproteins
~Glutathionine peroxidases: this enzyme inhibits and destroys natrually occuring peroxides that cause cell damage
~Deidinases: mediate the activeation and inactivation of thyroid hormone
~Selenoprotein P: protect aganist oxidative injury and to transport selenium from the liver to perpheral
~Selenoprotein W: antioxidant
Toxicity of Selenium results in?
- Blind staggers
- Abnormal hoof and hair growth
Deficiency of selenemium results in?
- White muscle liver disease
- Liver necrosis
This mineral is stored bound to ferritin, transported bound to transferrin
Iron
What are the function of Iron?
- Heme proteins
-hemoglobin
-myoglobin
-catalase - Proteins with Iron-sulfer centers
-aconitase
What are the functions of zinc?
- Zince metalloenzymes
-aminopeptidase
-fructose 1,6-biphosphate - Zinc finger proteins
- Lymphocytes
Deficiences of Zinc lead to?
- Decreased Growth
- Dermatitis
Function of Copper?
- Cu metalloenzymes
- Neutrophils and T Lymphocytes
- Iron metabolism
- Bone and vascular function
Deficiences of Copper lead to?
- Anemia
- Hair depigmentation
- Reduced growth
- Arotic rupture
- Abnormal bone formation
- GI disturbance
Manganese functions?
- Mn metalloenzymes
- Cartilage formation
Deficinecy of Mn symptoms are?
- Defective bone formation
- Perosis in poultry
Function of Sulfer?
- Required for microbial synthesis of sulfer—amino acids in the rumen
Deficiencies of Sulfer cause?
- Reduced weight gain
- Poor wool growth
Zinc, copper, and manganese are: ______ dimustases
Superoxide
What is superoxide dismutases?
Catalyze the reaction of free radical oxygen to hydrogen peroixide.
Glutathione peroxidase and catalase then catalyze reactions to convert hydrogen perioxide to water and oxygen.