Mineral Nutrition- Principles and Ca nutrition Flashcards
Name some functions of mineral nutrition (6)
structural enzymes/cofactors regulating osmotic pressure pH nerve and muscle function vitamin, blood cell and hormone synthesis
State 3 reasons why an animal might be deficient in minerals..
insufficient mineral in diet
low absorption
Mineral interactions
In digesta, minerals occur as: (3)
1) Metallic ions in solution (easily absorbed, eg Na+ and K+)
2) Constituents of metallo-organic substances (some absorbed, eg chelated)
3) Parts of insoluble substances (not absorbed)
Which is the most abundant mineral in the body?
Ca is the most abundant mineral in body, concentrated in bone
List 3 things that Ca is essential for in the body
bone and teeth development
enzyme systems for normal muscle and nerve function
blood clotting
List some sources of Ca (5)….
Milk green, leafy crops (legumes) animal products containing bone grains low limestone
Recommended Ca:P ratio??
between 1:1 to 2:1
Excessive P binds Ca reducing Ca absorption… True/ False?
True
Deficiency of vitamin D prevents proper Ca utilisation.. True/ False?
True
How is vitamin D synthesised?
Produced in skin by exposure to UV light
Where is Vit D stored?
Stored in liver
Good sources of Vit D?
Sunlight and sun-cured forages good sources
List some effects of Ca deficiency / P excess.. E.g. Rickets (5)
Young animals – rickets Young growing horses – DOD Osteomalacia in older animals brittle bone (osteoporosis in older animals) Milk fever
What is milk fever?
Clinical hypocalcaemia (milk fever or parturient paresis/paralysis)
List 3 symptoms of milk fever
Inappetence
Lateral recumbency
Coma and death
What is the most common mineral-related problem of the transition cow
hypocalcaemia (milk fever)
What causes hypocalcaemia?
Inability to absorb from gut and mobilise from bone enough Ca to meet sudden demand imposed on plasma Ca pool by lactogenesis
Excess K causes metabolic alkalosis.. How?
Reduces sensitivity of bone and renal tissue to PTH
Prevents up-regulation of 1, α-hydroxylase
Can hypomagnesaemia alter Ca homeostasis?
YES
How can hypomagnesaemia alter Ca homeostasis?
Less able to mobilise Ca- PTH and calcitriol secretion and activity retarded
Name one mineral that can alter plasma Mg
High dietary K can reduce plasma [Mg]
Can an excess of P induce hypocalcaemia?
Yes
How can an excess of P induce hypocalcaemia?
Inhibits PTH action on renal tissue
Apart from K, what other mineral has the potential to cause metabolic alkalosis?
Sodium, although most diets are low
List 2 dietary options for reducing milk fever..
Manipulating dietary cation-anion difference (DCAD) (feeding anionic salts)
Replenishing Ca reserves
Does lowering DCAD increase or reduce blood (and urine) pH?
It reduces blood and urine pH.
What effect does lowering DCAD have on Ca homeostasis?
Lowering DCAD reduces blood and urine pH, thus improving Ca homeostasis.
Should DCAD be positive or negative to protect against Milk Fever?
Negative
What can be used to assess DCAD?
Urine pH an indicator (6-7)
What is osteopetrosis?
Excess bone mass
Can excess Ca reduce absorption of Mn, Fe, Zn and Cu and P
Yes