Millers Questions Flashcards
Mechano receptor with low threshold. RESPONDS TO PRESSURE AND CURVATURE CHANGE. Change in cornea temperature could create a response
Piezo2
Polymodal receptors include
TRPV
TRPA
ASICS
TPRV
Vanilloid
Poly modal
Responds to temperature
TRPA
Polymodal
Ankylloid
Responds to chemicals
ASICS
Polymodal
Acid sensing ion channel
Low pH will cause a response
Cold receptors have ongoing activity in the cornea because of
Constant evaporation
TRPM8
Cold receptor
Menthol, cooling response, evaporation
In a phantom cornea there is ______ dyesthenia. Same response but the stimulus is ____. Abnormal ___. Activity.
Denervation induced dyesthenia
Stimulus is contain
Abnormal afferent activity
Dull ache
Steroids slow down
Corneal healing
When there is stimulus followed right after the other
Threshold drops
Sensitivity and response increases
Growth factors released that aid in epithelial healing
KGF, HGF, IGF2, PEDF
Epithelial wound will alwYS AFFECT THE STROMA BECAUSE
KERATOCYTES ARE GOING THROUGH APOPTOSIS
When do keratocyes differentiate into fibroblasts
Stroma corneal healing