MIDTERMS: Osteoperosis Flashcards

1
Q

❓ What is osteoporosis?

A

✅ A systemic skeletal disease characterized by low bone mass and deterioration of bone tissue, leading to increased fracture risk.

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2
Q

❓ What are the two main types of osteoporosis?

A

✅ Type 1 (Postmenopausal Osteoporosis) – Due to estrogen deficiency.
✅ Type 2 (Senile Osteoporosis) – Due to aging and calcium deficiency.

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3
Q

❓ What causes postmenopausal osteoporosis?

A

✅ Estrogen deficiency, leading to excessive osteoclast activity and bone resorption.

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4
Q

❓ What are common fracture sites in postmenopausal osteoporosis?

A

✅ Vertebrae, wrist, and hip.

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5
Q

❓ What medications are used for postmenopausal osteoporosis?

A

✅ Bisphosphonates, hormone replacement therapy (HRT), and selective estrogen receptor modulators (raloxifene).

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6
Q

❓ What causes senile osteoporosis?

A

✅ Aging and calcium/vitamin D deficiency, leading to reduced osteoblast activity.

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7
Q

❓ Who is at risk for senile osteoporosis?

A

✅ Individuals over 70 years old with poor calcium intake.

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8
Q

❓ What are common causes of secondary osteoporosis?

A

✅ Chronic diseases (hyperthyroidism, Cushing’s, RA) and long-term medication use (glucocorticoids, heparin, anticonvulsants).

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8
Q

❓ What are common fracture sites in senile osteoporosis?

A

✅ Hip and vertebrae.

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9
Q

❓ What are the key nutrients for osteoporosis prevention?

A

✅ Calcium (≥1200 mg/day) and Vitamin D (800-1000 IU/day).

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9
Q

❓ How does glucocorticoid use contribute to osteoporosis?

A

✅ It decreases bone formation and increases bone resorption.

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10
Q

❓ What is the best way to treat secondary osteoporosis?

A

✅ Address the underlying condition, optimize calcium & vitamin D intake, and use anti-osteoporotic medications if needed.

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11
Q

❓ Why is osteoporosis called the “silent disease”?

A

✅ It progresses without symptoms until a fracture occurs.

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12
Q

❓ What are common signs of osteoporosis?

A

✅ Fragility fractures, Dowager’s hump (kyphosis), height loss, and chronic back pain.

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12
Q

❓ What diagnostic test is used to assess osteoporosis?

A

✅ DEXA scan (Dual-Energy X-ray Absorptiometry) – Measures bone mineral density (BMD).

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13
Q

❓ What lifestyle changes help prevent osteoporosis?

A

✅ Weight-bearing exercise, fall prevention, and avoiding smoking & excessive alcohol.

14
Q

❓ What are some examples of weight-bearing exercises?

A

✅ Walking, jogging, dancing, and resistance training.

15
Q

❓ What surgical options exist for severe osteoporosis?

A

✅ Kyphoplasty and vertebroplasty – Procedures to stabilize vertebral fractures.

15
Q

✅ It occurs due to estrogen deficiency, leading to excessive osteoclast activity and rapid bone loss.

A

postmenopausal osteoporosis

16
Q

✅ Osteoporosis caused by aging and calcium deficiency, usually affecting individuals over 70 years old.

A

senile osteoporosis,

17
Q

❓ What are some causes of secondary osteoporosis?

A

✅ Chronic illnesses such as hyperthyroidism, rheumatoid arthritis, and Cushing’s syndrome, as well as long-term use of steroids, anticonvulsants, and heparin.